NIH-funded research R01 grant

Sacral nerve stimulation for chronic pelvic pain

Official title: Sacral neuromodulation for the management of chronic pelvic pain

Funded at William Beaumont Hospital Research Inst · NIH-11378507 · Data updated 2026-11-12

A study to see if a minimally invasive nerve-stimulation therapy can help reduce chronic pelvic pain and improve quality of life in adult women.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWilliam Beaumont Hospital Research Inst
NIH-funded
Lab location1 site (Royal Oak, United States)
Project startSeptember 20, 2023
Project endJuly 31, 2028
Funding year2026
Award (this year)$1,093,656
NIH project number4R01DK138839-04
Project IDNIH-11378507 on NIH RePORTER

Who could benefit from this research

Could help

Adult women with chronic pelvic pain who are candidates for neuromodulation therapy.

Less likely to help

Women without CPP or those not suitable for sacral neuromodulation may not benefit.

What this research studies

Chronic pelvic pain affects many women and can be hard to treat. This project will test sacral neuromodulation, a small implanted device that modulates nerve signals to the pelvic region, as a potential therapy for CPP. Researchers will follow participants over time to see changes in pain, function, mood, and daily living, using standardized assessments. The study builds on prior data showing improvements in related pelvic conditions and aims to clarify its effect on CPP specifically.

Why it matters

Potential benefit: If successful, this approach could offer a new, minimally invasive option to reduce pelvic pain and improve daily functioning for women with CPP.

How similar studies have gone: Past studies suggest potential pain reduction with sacral neuromodulation, but prospective CPP-specific evidence is limited.

Where this research is happening

  • William Beaumont Hospital Research Inst
    Royal Oak, United States
    Active

Researchers

  • Principal investigator: Peters, Kenneth M — William Beaumont Hospital Research Inst
  • Study coordinator: Peters, Kenneth M

Related research

Other NIH-funded projects on the same topics.

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  • Dual Cromolyn-Cetirizine oral capsule to help men with chronic pelvic pain

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  • Why menstrual pain becomes chronic pelvic pain

    We will follow young women with menstrual pain, including those with bladder sensitivity, to learn who develops ongoing pelvic pain and which early signs predict it.

    NIH research Endeavor Health Clinical Operations · Evanston, United States · NIH-11349686

  • Sacral Neuromodulation for Chronic Pelvic Pain

    This research explores if a treatment called sacral neuromodulation can help women who experience ongoing pelvic pain.

    NIH research William Beaumont Hospital Research Inst · Royal Oak, United States · NIH-11168899

  • A brief behavioral treatment for chronic pelvic pain

    This project is testing a short behavioral therapy to help people manage chronic pelvic pain and related conditions like irritable bowel syndrome.

    NIH research State University of New York at Buffalo · Amherst, United States · NIH-11159501

  • Chemical Clues in Chronic Pelvic Pain

    This project looks for unique chemical patterns in the body that could help us better understand and treat chronic pelvic pain in men and women.

    NIH research Washington University · Saint Louis, United States · NIH-11143622

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.