Chemical Clues in Chronic Pelvic Pain
Metabolomic Signatures of Urologic Chronic Pelvic Pain Syndrome
This project looks for unique chemical patterns in the body that could help us better understand and treat chronic pelvic pain in men and women.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11143622 on NIH RePORTER |
What this research studies
Urologic Chronic Pelvic Pain Syndrome (UCPPS) causes severe symptoms like urinary urgency, frequency, and pain for millions of people. We don't fully understand what causes these symptoms, which makes diagnosis and treatment difficult. This project uses advanced techniques to find specific chemical signals in human samples from a large research network. By identifying these unique chemical patterns, we hope to uncover different types of UCPPS and develop new ways to diagnose and treat this condition.
Who could benefit from this research
Good fit: Patients experiencing chronic urologic pain disorders such as interstitial cystitis/bladder pain syndrome (IC/BPS) or chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) are the focus of this research.
Not a fit: Patients without symptoms of urologic chronic pelvic pain syndrome would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new diagnostic tests and more effective treatments tailored to specific types of chronic pelvic pain.
How similar studies have performed: Previous work by this team has already identified elevated levels of a specific steroid in a subgroup of female UCPPS patients, suggesting this approach has promise.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Henderson, Jeffrey P — Washington University
- Study coordinator: Henderson, Jeffrey P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.