Understanding how menstrual pain can lead to chronic pelvic pain
Targeting Interindividual Variability in NSAID Responses to Mitigate Chronic Pelvic Pain Risk in Dysmenorrhea
This study is looking at how painful periods might lead to long-term pelvic pain and how inflammation and nerve changes play a role, so we can find better ways to help women manage their pain and prevent it from getting worse.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Endeavor Health Clinical Operations NIH-funded |
| Lab location | 1 site (Evanston, United States) |
| Project ID | NIH-11023728 on NIH RePORTER |
What this research studies
This research investigates the relationship between menstrual pain (dysmenorrhea) and the risk of developing chronic pelvic pain (CPP). It aims to understand how local inflammation in the uterus and changes in the nervous system contribute to painful periods. By examining individual responses to common anti-inflammatory medications, the study seeks to identify ways to prevent the progression of dysmenorrhea into more severe conditions like bladder pain syndrome and endometriosis. The research employs various sensory tests and advanced brain imaging techniques to explore these interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing dysmenorrhea, particularly those at risk of developing chronic pelvic pain.
Not a fit: Patients who do not experience menstrual pain or have already developed chronic pelvic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatments for menstrual pain and reduce the risk of developing chronic pelvic pain.
How similar studies have performed: Previous research has shown promise in understanding pain mechanisms and treatment responses, suggesting that this approach could yield valuable insights.
Where this research is happening
Evanston, United States
- Endeavor Health Clinical Operations — Evanston, United States (Active)
Researchers
- Principal investigator: Hellman, Kevin — Endeavor Health Clinical Operations
- Study coordinator: Hellman, Kevin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.