Understanding chronic pelvic pain and its causes
Preclinical phenotypic modeling of chronic urologic pelvic pain
This study is looking into how early life experiences and stress might change the way our bodies feel pain in the pelvic area, which could help find new ways to treat chronic pelvic pain conditions like interstitial cystitis and chronic prostatitis.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11116883 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind chronic urologic pelvic pain syndrome (UCPPS), which includes conditions like interstitial cystitis and chronic prostatitis. By using animal models, the study aims to explore how early life events and stress can alter the way the nervous system processes pain signals from the pelvic region. The researchers will examine the effects of neonatal bladder inflammation and maternal separation, along with adult stressors, to understand their impact on pain sensitivity. This work could lead to new therapeutic targets for managing chronic pelvic pain.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic pelvic pain or related urologic conditions.
Not a fit: Patients with acute, non-chronic pelvic pain or those without any urologic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals suffering from chronic pelvic pain conditions.
How similar studies have performed: Previous research has shown promising results in understanding pain mechanisms through similar animal model approaches, indicating potential for success in this area.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Deberry, Jennifer J — University of Alabama at Birmingham
- Study coordinator: Deberry, Jennifer J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.