Understanding the causes of chronic pelvic pain in women

Cross Organ Mechanisms in Chronic Pelvic Pain

NIH-funded research Endeavor Health Clinical Operations · NIH-11136242

This study is looking at why some young women with menstrual pain end up with long-lasting pelvic pain, and it will follow them for two years to find out what factors might increase the risk of developing this chronic pain.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionEndeavor Health Clinical Operations NIH-funded
Lab location1 site (Evanston, United States)
Project IDNIH-11136242 on NIH RePORTER

What this research studies

This research investigates why some women with menstrual pain develop chronic pelvic pain (CPP) while others do not. It focuses on a specific group of young women who experience dysmenorrhea and tracks their symptoms over two years to identify risk factors for developing CPP. The study includes assessments of bladder sensitivity and other health factors to better understand the transition from acute to chronic pain. By gathering data from a large cohort, the research aims to uncover underlying mechanisms that contribute to CPP.

Who could benefit from this research

Good fit: Ideal candidates for this research are young women experiencing dysmenorrhea, particularly those showing signs of bladder hypersensitivity.

Not a fit: Patients who do not experience menstrual pain or chronic pelvic pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for women suffering from chronic pelvic pain.

How similar studies have performed: Previous studies have shown promising results in understanding chronic pain mechanisms, but this specific approach focusing on dysmenorrhea and its transition to CPP is relatively novel.

Where this research is happening

Evanston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.