A new treatment approach for chronic pelvic pain conditions
Official title: A BRIEF, TRANSDIAGNOSTIC COGNITIVE BEHAVIORAL TREATMENT FOR UROLOGIC CHRONIC PELVIC PAIN SYNDROME (UCPPS): PROCESS, PREDICTIONS, OUTCOMES
Funded at State University of New York at Buffalo · NIH-10896160 · Data updated 2026-11-12
This study is testing a short therapy program that helps people with chronic pelvic pain learn ways to manage their symptoms, and it's open to anyone dealing with this kind of pain, including those with related issues like irritable bowel syndrome or fibromyalgia.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project start | September 21, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $609,039 |
| NIH project number | 5R01DK128927-04 |
| Project ID | NIH-10896160 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 18-70 who experience symptoms of urologic chronic pelvic pain syndrome.
✕Less likely to help
Patients with acute pelvic pain or those who do not have a diagnosis of UCPPS may not benefit from this research.
What this research studies
This research investigates a brief cognitive behavioral treatment designed for individuals suffering from urologic chronic pelvic pain syndrome (UCPPS). The approach focuses on teaching patients skills to manage their symptoms, which may include pelvic pain and urinary issues. By targeting the underlying cognitive patterns associated with pain, the treatment aims to alleviate not only UCPPS but also related conditions like irritable bowel syndrome and fibromyalgia. The study will involve 240 participants who will be randomized to receive this innovative treatment over four sessions.
Why it matters
Potential benefit: If successful, this research could provide a more effective and accessible treatment option for patients suffering from chronic pelvic pain and its associated conditions.
How similar studies have gone: Previous research has shown promise in using cognitive behavioral therapy for chronic pain conditions, suggesting that this approach may be effective for UCPPS as well.
Where this research is happening
-
State University of New York at Buffalo
Amherst, United States Active
Researchers
- Principal investigator: Lackner, Jeffrey M — State University of New York at Buffalo
- Study coordinator: Lackner, Jeffrey M
Related research
Other NIH-funded projects on the same topics.
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Exploring allergy-based triggers to prevent UCPPS flare-ups
A short, patient-friendly study will look at whether allergy-related antibodies can help predict and prevent flare-ups in people with urologic chronic pelvic pain syndrome.
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Dual Cromolyn-Cetirizine oral capsule to help men with chronic pelvic pain
A new oral medicine combining cromolyn sodium and cetirizine is being developed to help adults with chronic prostatitis/chronic pelvic pain by targeting immune and nerve-related pathways.
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A brief behavioral treatment for chronic pelvic pain
This project is testing a short behavioral therapy to help people manage chronic pelvic pain and related conditions like irritable bowel syndrome.
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Chemical Clues in Chronic Pelvic Pain
This project looks for unique chemical patterns in the body that could help us better understand and treat chronic pelvic pain in men and women.
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Using glial cells to reduce visceral pain in bladder conditions
This study is looking at how certain cells in the nervous system can be activated to help reduce the pain that comes with chronic pelvic pain syndrome, especially for those dealing with bladder issues, and it aims to find new treatment options that could eventually help people like you.
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Improving treatment for chronic pelvic pain in men
This study is looking to create a new oral medication to help men under 50 who suffer from chronic prostatitis/chronic pelvic pain syndrome, by combining two types of medicine that have shown promise, and it will first test these new formulas in dogs to find the best one before trying it in people.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.