A device for pain relief using temperature modulation
Official title: Targeted Temperature Modulation with Smart Radiometric Monitoring for Effective and Long-Lasting Opioid-Free Pelvic Pain Relief - A Novel Low-Cost, Portable, Tampon-sized Thermal Transfer Device.
Funded at H3pelvic Therapy Systems, INC. · NIH-10760002 · Data updated 2026-11-12
This study is testing a new, easy-to-use device that helps relieve pelvic pain by using heat, so you can feel better without relying on painkillers like opioids.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H3pelvic Therapy Systems, INC. NIH-funded |
| Lab location | 1 site (Lewisville, United States) |
| Project start | September 25, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $384,737 |
| NIH project number | 1R43HD112219-01A1 |
| Project ID | NIH-10760002 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic pelvic pain conditions such as endometriosis, interstitial cystitis, or overactive bladder.
✕Less likely to help
Patients with acute pelvic pain or those who do not experience pelvic pain may not benefit from this research.
What this research studies
This research investigates a novel, portable thermal transfer device designed to provide effective pain relief for pelvic pain without the use of opioids. The device works by modulating temperature in the pelvic area, which has shown promise in alleviating pain and reducing urinary frequency. Patients will be able to use this device comfortably, potentially improving their quality of life. The approach aims to offer a low-cost alternative to existing pain management therapies that often lose effectiveness over time.
Why it matters
Potential benefit: If successful, this research could provide a non-opioid solution for managing pelvic pain, significantly improving patients' quality of life.
How similar studies have gone: Previous studies have shown that thermal modulation can effectively relieve pelvic pain, suggesting that this approach may be promising.
Where this research is happening
-
H3pelvic Therapy Systems, INC.
Lewisville, United States Active
Researchers
- Principal investigator: Lyon, Zachary W — H3pelvic Therapy Systems, INC.
- Study coordinator: Lyon, Zachary W
Related research
Other NIH-funded projects on the same topics.
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A short, patient-friendly study will look at whether allergy-related antibodies can help predict and prevent flare-ups in people with urologic chronic pelvic pain syndrome.
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Targeted pelvic warmth/cooling device to relieve pelvic pain
A low-cost, portable device uses controlled temperature changes to soothe pelvic pain from conditions like endometriosis and bladder issues, with the goal of reducing pain and inflammation without opioids.
-
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A new oral medicine combining cromolyn sodium and cetirizine is being developed to help adults with chronic prostatitis/chronic pelvic pain by targeting immune and nerve-related pathways.
-
Sacral nerve stimulation for chronic pelvic pain
A study to see if a minimally invasive nerve-stimulation therapy can help reduce chronic pelvic pain and improve quality of life in adult women.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.