Understanding the role of the immune system in chronic pelvic pain
Neuroimmune Interface in Urological Chronic Pelvic Pain Syndrome
This study is looking at how inflammation and immune responses might affect the nervous system in people with Urologic Chronic Pelvic Pain Syndrome (UCPPS) and other pain issues, to help find better ways to treat this painful condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10767260 on NIH RePORTER |
What this research studies
This research investigates Urologic Chronic Pelvic Pain Syndrome (UCPPS), a condition causing significant bladder and pelvic pain along with urinary symptoms. The study aims to explore how inflammation and immune responses affect the central nervous system in patients with UCPPS, particularly those with additional pain syndromes. By analyzing blood samples and using advanced imaging techniques, researchers hope to uncover the underlying mechanisms of this complex condition and improve treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Urologic Chronic Pelvic Pain Syndrome, especially those experiencing additional pain conditions.
Not a fit: Patients without UCPPS or those whose pain is not related to immune system responses may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of chronic pelvic pain, potentially improving the quality of life for affected patients.
How similar studies have performed: Previous research within the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) has shown promising results in understanding the immune response in UCPPS, indicating that this approach has potential for success.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Harte, Steven Edward — University of Michigan at Ann Arbor
- Study coordinator: Harte, Steven Edward
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.