Improving treatment for chronic pelvic pain in men

Optimizing Dual Therapy for Chronic Prostatitis/Chronic Pelvic Pain Syndrome

['FUNDING_OTHER'] · DOLOR THERAPEUTICS, LLC · NIH-10918611

This study is looking to create a new oral medication to help men under 50 who suffer from chronic prostatitis/chronic pelvic pain syndrome, by combining two types of medicine that have shown promise, and it will first test these new formulas in dogs to find the best one before trying it in people.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorDOLOR THERAPEUTICS, LLC (nih funded)
Locations1 site (CHICAGO, UNITED STATES)
Trial IDNIH-10918611 on ClinicalTrials.gov

What this research studies

This research focuses on chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), a common condition affecting men under 50. The study aims to develop a new oral medication that combines a mast cell stabilizer and a histamine receptor antagonist, which has shown promise in previous pilot studies. By enhancing the absorption of these medications through optimized formulations, the goal is to create a more effective and easier treatment option for patients. The research will involve testing these formulations in dogs to determine the best option before moving to human trials.

Who could benefit from this research

Good fit: Ideal candidates for this research are men under 50 who are experiencing chronic pelvic pain or prostatitis.

Not a fit: Patients who do not have chronic prostatitis or chronic pelvic pain syndrome may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more effective and convenient treatment for men suffering from chronic pelvic pain.

How similar studies have performed: Previous pilot studies have shown success with similar approaches, indicating potential for this research to build on those findings.

Where this research is happening

CHICAGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.