Effects of bariatric surgery on the medication irbesartan
Official title: Bariatric Surgery and Pharmacokinetics Irbesartan: BAR-MEDS Irbesartan
Run by Norwegian University of Science and Technology · NCT03476603 · Data updated 2026-11-12
This study looks at how bariatric surgery affects the way the body processes the medication irbesartan in patients getting ready for surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 12 (estimated) |
| Sponsor | Norwegian University of Science and Technology Academic / other |
| Locations | 1 site (Trondheim) |
| Status | Recruiting |
| Started | November 2, 2016 |
| Main results expected | October 2026 |
| Study ends | October 2026 |
| Registry record updated | July 8, 2026 |
| Trial ID | NCT03476603 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Norwegian citizens preparing to undergo gastric bypass or sleeve gastrectomy.
✕Probably not a fit
Patients who have previously undergone resections in the gastrointestinal tract may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates how bariatric surgery, specifically gastric bypass and sleeve gastrectomy, affects the pharmacokinetics of the medication irbesartan. It aims to understand changes in gastric pH, gastric emptying time, and gastrointestinal transit-time that may influence the biological availability of this drug. The study is conducted in Central Norway and focuses on patients preparing for these surgical procedures. By analyzing these pharmacokinetic changes, the research seeks to provide insights into medication management post-surgery.
Why it matters
Potential benefit: If successful, this study could lead to improved medication management for patients undergoing bariatric surgery.
How similar studies have gone: While there is limited information on similar studies, the investigation into pharmacokinetics post-bariatric surgery is a relatively novel area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway * Being a Norwegian citizen Exclusion Criteria: * Having previously undergone resections in the GI-tract
Where it's running
-
St. Olavs University Hospital
Trondheim, Norway Recruiting
Study contacts
- Principal investigator: Magnus Strømmen, MSc — St. Olavs Hospital
- Study coordinator: Magnus Strømmen, MSc
- Email: magnus.strommen@stolav.no
- Phone: 0047 72829970
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Glycemic variability after SASI versus Roux-en-Y gastric bypass
This trial tests whether SASI or Roux-en-Y gastric bypass leads to different glucose fluctuations in adults with severe obesity using continuous glucose monitoring.
-
Postoperative nausea, vomiting and pain after bariatric surgery in Sweden
This study looks at how often people have nausea, vomiting, and pain after bariatric surgery in Sweden and whether anesthesia type or regional blocks affect those outcomes.
-
Low-impact laparoscopy for sleeve gastrectomy in adults with obesity
This will see if low-pressure, small-incision laparoscopy reduces post-surgery pain and improves breathing after sleeve gastrectomy in adults with obesity.
-
Tranexamic acid to reduce bleeding in sleeve gastrectomy and mini gastric bypass
This trial will test whether giving tranexamic acid before laparoscopic sleeve gastrectomy or mini gastric bypass reduces bleeding in adults with morbid obesity.
-
Predicting Quality of Life After Bariatric Surgery from Pre-Surgery Profiles
This study tests whether pre-surgical patient traits can predict how quality of life changes after bariatric surgery for adults in the GEROM73 program.
-
Endoscopic treatment for overweight and mild obesity using Orbera365
This study is testing whether the Orbera365 intragastric balloon can help people who are overweight or mildly obese lose weight over a year.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.