Impact of bariatric surgery on lamotrigine absorption

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how bariatric surgery, specifically gastric bypass and sleeve gastrectomy, affects the pharmacokinetics of lamotrigine, a medication used for epilepsy and mood stabilization. It aims to understand changes in gastric pH, gastric emptying time, and gastrointestinal transit-time that may influence the biological availability of lamotrigine post-surgery. The study is conducted in Central Norway and focuses on patients preparing for these surgical procedures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway
* Being a Norwegian citizen

Exclusion Criteria:

* Having previously undergone resections in the GI-tract

Where it's running

• St. Olavs University Hospital
  Trondheim, Norway Recruiting

Study contacts

• Principal investigator: Magnus Strømmen, MSc — St. Olavs Hospital
• Study coordinator: Magnus Strømmen, MSc
• Email: magnus.strommen@stolav.no
• Phone: 0047 72829970

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Glycemic variability after SASI versus Roux-en-Y gastric bypass

  This trial tests whether SASI or Roux-en-Y gastric bypass leads to different glucose fluctuations in adults with severe obesity using continuous glucose monitoring.

  Recruiting Hospitales Universitarios Virgen del Rocío · Seville, Sevilla · NCT07872397

• Postoperative nausea, vomiting and pain after bariatric surgery in Sweden

  This study looks at how often people have nausea, vomiting, and pain after bariatric surgery in Sweden and whether anesthesia type or regional blocks affect those outcomes.

  Recruiting at 2 sites Umeå University · Sundsvall and 1 other locations · NCT07797374

• Low-impact laparoscopy for sleeve gastrectomy in adults with obesity

  This will see if low-pressure, small-incision laparoscopy reduces post-surgery pain and improves breathing after sleeve gastrectomy in adults with obesity.

  Recruiting Fondazione Policlinico Universitario Campus Bio-Medico · Rome, Italy · NCT07119437

• Tranexamic acid to reduce bleeding in sleeve gastrectomy and mini gastric bypass

  This trial will test whether giving tranexamic acid before laparoscopic sleeve gastrectomy or mini gastric bypass reduces bleeding in adults with morbid obesity.

  Recruiting Phase 4 Patel Hospital, Pakistan · Karachi, Sindh · NCT07098780

• Predicting Quality of Life After Bariatric Surgery from Pre-Surgery Profiles

  This study tests whether pre-surgical patient traits can predict how quality of life changes after bariatric surgery for adults in the GEROM73 program.

  Recruiting Centre Hospitalier Metropole Savoie · Chambéry, Savoie · NCT06951893

• Endoscopic treatment for overweight and mild obesity using Orbera365

  This study is testing whether the Orbera365 intragastric balloon can help people who are overweight or mildly obese lose weight over a year.

  Recruiting Kaiser Clinic and Hospital · Santo André, São Paulo · NCT06785233

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.