Impact of bariatric surgery on the effectiveness of hydrochlorothiazide

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how bariatric surgery, specifically gastric bypass and sleeve gastrectomy, affects the pharmacokinetics of hydrochlorothiazide, a medication commonly used to treat high blood pressure. It aims to understand changes in gastric pH, gastric emptying time, and gastrointestinal transit-time that may influence the biological availability of this drug. The study is conducted in Central Norway, focusing on patients preparing for these surgical procedures. By examining these pharmacokinetic changes, the research seeks to provide insights into medication management for patients post-surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway
* Being a Norwegian citizen

Exclusion Criteria:

* Having previously undergone resections in the GI-tract

Where it's running

• St. Olavs University Hospital
  Trondheim, Norway Recruiting

Study contacts

• Principal investigator: Magnus Strømmen, MSc — St. Olavs Hospital
• Study coordinator: Magnus Strømmen, MSc
• Email: magnus.strommen@stolav.no
• Phone: 0047 72829970

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.