Clinical trial Recruiting at 1 site Observational Ages 18 to 70

Impact of Bariatric Surgery on Ramipril Absorption

Official title: Bariatric Surgery and Pharmacokinetics of Ramipril: BAR-MEDS Ramipril

Run by Norwegian University of Science and Technology · NCT03440177 · Data updated 2026-11-12

This study is testing how bariatric surgery affects the way the body absorbs the heart medication ramipril in people who have had gastric bypass or sleeve gastrectomy.

Quick facts

Study typeObservational
Ages18 Years to 70 Years
SexAll
Enrollment12 (estimated)
SponsorNorwegian University of Science and Technology
Academic / other
Locations1 site (Trondheim)
StatusRecruiting
StartedJanuary 2, 2018
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedJuly 8, 2026
Trial IDNCT03440177 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are Norwegian citizens preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway.

Probably not a fit

Patients who have previously undergone resections in the gastrointestinal tract may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how bariatric surgery, specifically gastric bypass and sleeve gastrectomy, affects the pharmacokinetics of the medication ramipril. It aims to understand changes in gastric pH, gastric emptying time, and gastrointestinal transit-time that may influence the biological availability of this drug. By examining these factors, the study seeks to provide insights into medication management for patients undergoing these surgical procedures.

Why it matters

Potential benefit: If successful, this study could lead to improved medication management for patients undergoing bariatric surgery, enhancing the effectiveness of ramipril.

How similar studies have gone: While there is limited research on this specific topic, similar studies have shown that bariatric surgery can significantly alter drug pharmacokinetics, suggesting potential for meaningful findings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway
* Being a Norwegian citizen

Exclusion Criteria:

* Having previously undergone resections in the GI-tract

Where it's running

  • St. Olavs University Hospital
    Trondheim, Norway
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.