Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Characterizing diabetes and obesity in Greenlandic patients

Official title: Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland

Run by Steno Diabetes Center Greenland · NCT06264427 · Data updated 2026-11-12

This study is trying to learn more about how genetics and environment affect type 2 diabetes and obesity in Greenlandic people, while also looking at related health issues like sleep apnea.

More Obstructive Sleep Apnea trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorSteno Diabetes Center Greenland
Academic / other
Locations1 site (Nuuk, Sermersooq)
StatusRecruiting
StartedJuly 15, 2022
Main results expectedDecember 31, 2025
Study endsDecember 31, 2026
Registry record updatedFebruary 20, 2024
Trial IDNCT06264427 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years old with type 2 diabetes and/or morbid obesity (BMI > 40).

Probably not a fit

Patients who do not speak English, Danish, or Greenlandic will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to explore the phenotypic and genotypic characteristics of individuals with type 2 diabetes and severe obesity in Greenland. It focuses on understanding the unique genetic and environmental interactions that influence disease progression in the Greenlandic Inuit population. The study employs whole genome sequencing to identify specific genetic variants linked to insulin resistance and maturity-onset diabetes, while also assessing the prevalence of obstructive sleep apnea among high-risk individuals. Participants will undergo clinical evaluations and complete questionnaires to provide insights into their quality of life and functional outcomes.

Why it matters

Potential benefit: If successful, this study could lead to improved personalized treatment strategies for diabetes and obesity in the Greenlandic population.

How similar studies have gone: While similar studies have explored genetic factors in diabetes, this specific focus on the Greenlandic Inuit population and their unique genetic and environmental context is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Type 2 diabetes and/or morbid obesity (BMI \>40)
* Over 18 years old

Exclusion Criteria:

* Does not speak either English, Danish or Greenlandic

Where it's running

  • Steno Diabetes Center Greenland, Queen Ingrids Hospital
    Nuuk, Sermersooq, Greenland
    Recruiting

Study contacts

  • Principal investigator: Marit Eika Jørgensen, Md. Phd — Steno Diabetes Center Greenland
  • Study coordinator: Mads Jensen, MD.
  • Email: MMSN@peqqik.gl
  • Phone: +299 34 46 23

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.