Characterizing diabetes and obesity in Greenlandic patients
Official title: Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland
Run by Steno Diabetes Center Greenland · NCT06264427 · Data updated 2026-11-12
This study is trying to learn more about how genetics and environment affect type 2 diabetes and obesity in Greenlandic people, while also looking at related health issues like sleep apnea.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Steno Diabetes Center Greenland Academic / other |
| Locations | 1 site (Nuuk, Sermersooq) |
| Status | Recruiting |
| Started | July 15, 2022 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2026 |
| Registry record updated | February 20, 2024 |
| Trial ID | NCT06264427 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old with type 2 diabetes and/or morbid obesity (BMI > 40).
✕Probably not a fit
Patients who do not speak English, Danish, or Greenlandic will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to explore the phenotypic and genotypic characteristics of individuals with type 2 diabetes and severe obesity in Greenland. It focuses on understanding the unique genetic and environmental interactions that influence disease progression in the Greenlandic Inuit population. The study employs whole genome sequencing to identify specific genetic variants linked to insulin resistance and maturity-onset diabetes, while also assessing the prevalence of obstructive sleep apnea among high-risk individuals. Participants will undergo clinical evaluations and complete questionnaires to provide insights into their quality of life and functional outcomes.
Why it matters
Potential benefit: If successful, this study could lead to improved personalized treatment strategies for diabetes and obesity in the Greenlandic population.
How similar studies have gone: While similar studies have explored genetic factors in diabetes, this specific focus on the Greenlandic Inuit population and their unique genetic and environmental context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Type 2 diabetes and/or morbid obesity (BMI \>40) * Over 18 years old Exclusion Criteria: * Does not speak either English, Danish or Greenlandic
Where it's running
-
Steno Diabetes Center Greenland, Queen Ingrids Hospital
Nuuk, Sermersooq, Greenland Recruiting
Study contacts
- Principal investigator: Marit Eika Jørgensen, Md. Phd — Steno Diabetes Center Greenland
- Study coordinator: Mads Jensen, MD.
- Email: MMSN@peqqik.gl
- Phone: +299 34 46 23
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.