Condition

Allergy clinical trials and research

• 18Clinical trials
• 127NIH research projects
• 1New in 30 days
• 10Countries

Newest Allergy clinical trials

All recruiting trials (18)

• What the Mayo Clinic is learning from blood clot tests in allergic reactions

  This study tests whether real-time blood clotting markers can help understand and predict the severity of allergic reactions and anaphylaxis in patients 12 and older.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07905911

• Does having allergic parents raise the chance of bronchiolitis in babies by 12 months?

  We’re testing if infants with at least one allergic parent are more likely to have bronchiolitis by 12 months compared to infants whose parents have no allergies.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens, Picardie · NCT07832643

• Using alpha-gal KO pork to see if it reduces reactions in people with Alpha-gal Syndrome

  This study tests whether eating pork that lacks the alpha-gal allergen lowers reaction risk for people with Alpha-gal Syndrome, using a crossover design where each participant tries both KO and wild-type pork on separate days.

  Recruiting Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Little Rock, Arkansas and 3 other locations · NCT07611435

• Lymph node examination during cat allergy immunotherapy

  This project will test how lymph nodes react after a small cat allergen skin challenge in people with cat allergy who are either on long-term allergy shots or have never had immunotherapy.

  Recruiting Early Phase 1 National Institute of Allergy and Infectious Diseases (NIAID) · Boston, Massachusetts · NCT07447869

• How classroom indoor air affects children's allergies and wellbeing

  This project will test whether continuous classroom and home air pollutant monitoring can identify pollution patterns linked to worse allergy or asthma symptoms in school-age children.

  Recruiting University Hospital, Montpellier · Montpellier · NCT07402200

• Beltaven shots for allergy to honeybee, paper wasp, or yellow jacket

  This project will try subcutaneous Beltaven allergy shots in people aged 14 and up who have had systemic reactions to Apis mellifera, Polistes dominula, or Vespula stings to see if they are safe and helpful in routine care.

  Recruiting at 13 sites Probelte Pharma S.L.U. · Barcelona, Barcelona and 12 other locations · NCT07309822

• Biomarkers that predict peanut allergy reactions during a feeding test

  This study tests whether biomarkers can predict which children and teens will react during a peanut oral food challenge.

  Recruiting at 8 sites National Institute of Allergy and Infectious Diseases (NIAID) · Little Rock, Arkansas and 9 other locations · NCT07279467

• Direct oral antibiotic challenge to remove beta-lactam allergy label in children in private clinics

  This study will try giving a supervised small dose of a beta-lactam antibiotic in private pediatric clinics to see if children labeled as allergic actually tolerate it.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07002814

• Long-term effects of jack jumper ant venom immunotherapy

  This trial will test whether people who completed 3–6 years of jack jumper ant venom immunotherapy still have protection when given a supervised sting challenge after being off treatment for 18 months to 5 years.

  Recruiting at 3 sites Phase 4 Murdoch Childrens Research Institute · Adelaide, South Australia and 2 other locations · NCT06935890

• Long-term monitoring of adults with type I interferon autoantibodies or genetic interferon defects

  We will follow adults who have autoantibodies to type I interferons or genetic defects that impair interferon responses to see if they develop more infections or autoimmune problems and how antibody levels change over time.

  Recruiting at 9 sites Institut National de la Santé Et de la Recherche Médicale, France · Lille and 8 other locations · NCT06762002

• Vitamin D supplementation during pregnancy to prevent early childhood asthma

  This study is testing if giving high-dose vitamin D to pregnant women can help prevent asthma and wheezing in their children by the time they reach three years old.

  Recruiting Phase 3 Copenhagen Studies on Asthma in Childhood · Gentofte Municipality · NCT06570889

• Fish oil supplementation during pregnancy to prevent asthma in children

  This study is testing if taking high-dose fish oil during pregnancy can help reduce the chances of children developing asthma and breathing problems.

  Recruiting Phase 3 Copenhagen Studies on Asthma in Childhood · Gentofte Municipality · NCT06560255

• Research on improving kindergarten yards for children's health

  This study is testing whether making kindergarten yards more natural and full of plants can improve the health and learning of children aged 1-5 by looking at things like allergies, asthma, and their overall well-being.

  Recruiting at 2 sites Natural Resources Institute Finland · Helsinki, Uusimaa and 1 other locations · NCT06390878

• Analyzing immune system issues in patients

  This study is trying to collect blood and stool samples from people with immune system problems and healthy individuals to better understand these issues and help improve treatments.

  Recruiting Karolinska Institutet · Stockholm · NCT06248957

• Wheat oral immunotherapy for children with wheat allergy

  This study is testing if giving different doses of wheat oral immunotherapy can help children with wheat allergies feel better and manage their reactions over a year.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06069492

• Modified measles vaccination schedule to prevent allergies and infections in children

  This study is testing a new timing for the measles vaccine in kids to see if it can help prevent allergies and infections better than the usual schedule.

  Recruiting Phase 4 Pediatric Clinical Research Platform · Geneva · NCT05758532

• Follow-up on children from the TEMPO study regarding allergies and infections

  This study is following children from the TEMPO study to see how their early feeding habits affect their chances of developing allergies and infections as they grow up.

  Recruiting Nutricia Research · Beek · NCT05449756

• Understanding allergies in healthy and allergic individuals

  This study looks at how allergies work in both healthy people and those with allergies to see if it can help improve how allergies are diagnosed and treated.

  Recruiting Stanford University · Palo Alto, California · NCT04828603

NIH-funded research (newest 40 of 127)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• New Horizons in preventing and treating food allergy

  A Johns Hopkins-led effort aims to advance how we prevent and treat food allergies across all ages by coordinating high-quality studies and developing better therapies.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600582

• Understanding antibiotic allergy to improve care for patients

  Scientists are testing new ideas to understand why some people develop severe allergic reactions to antibiotics and how to prevent or treat them.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11593203

• Antibiotic Allergy: Types, Triggers, and How they Work

  This grant aims to better understand why certain antibiotics trigger immediate allergic reactions and how to improve testing and diagnosis for patients with suspected antibiotic allergies.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11592359

• Understanding alpha-gal meat allergy and how the body's immune system reacts

  This grant studies why some people develop a dangerous allergy to meat due to a molecule called alpha-gal and how it triggers life-threatening reactions.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11588253

• New Horizons in Food Allergy Prevention and Treatment

  A large, multi-site program at Johns Hopkins aims to advance prevention and treatment of food allergies across all ages.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11580809

• Food allergy outcomes by race/ethnicity from infancy through adolescence

  This study follows children with food allergies over time to understand how race and ethnicity relate to allergy management, outcomes, and quality of life.

  NIH research Northwestern University · Chicago, United States · NIH-11579222

• Gut-brain links in food allergy responses

  A research grant is exploring how signals between the gut and brain drive dangerous reactions to foods, with the goal of helping people with food allergies.

  NIH research Yale University · New Haven, United States · NIH-11551492

• Targeting gut microbes to restore food-tolerance in adults

  Aims to understand how gut bacteria and the lining of the gut interact to keep people with food allergies tolerant to what they eat.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11551491

• Stopping Atopic Dermatitis and Allergy: Preventing Food Allergy by Protecting the Skin

  A large study in infants at high risk for allergies tests whether using a skin barrier cream together with early, proactive skin care can prevent peanut allergy and other food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11532535

• SEAL Study: Preventing peanut allergy by protecting baby skin

  This trial tests whether using a skin-emollient and proactive skin steroids early in life can prevent peanut allergy in high-risk infants.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11532533

• SEAL Study: Prevent allergy by protecting the baby’s skin

  A very young group of high-risk babies will try a early skin-care plan to reduce eczema and prevent peanut allergy.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11516452

• Safety of a standardized egg ladder for children with egg allergy

  A first-in-children study tests a simple, at-home stepwise egg exposure plan to make egg allergy management safer and easier.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11453575

• Environment and early-life exposures shaping food allergy in children

  This grant looks at how a child’s first year and their home environment may influence whether they develop food allergies, focusing on indoor exposures and microbes.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11450430

• Type 2 memory B cells and allergy persistence

  A scientist-offered project will study how a specific group of memory B cells may keep allergic reactions going, especially for peanut and other common allergens, with the goal of understanding why allergies persist.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11449948

• Longitudinal metabolomics in infants with food allergies

  A study in infants aims to understand how gut metabolites relate to the development of food allergies, including IgE-mediated and non-IgE cases.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11440939

• Childhood Allergy and the Neonatal Environment: Early Life Airways and Asthma

  A long-term study following newborns to age 5 to understand how early-life nose and airway biology, immune development, and the environment influence asthma risk.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11430311

• Adapting penicillin allergy checks in outpatient clinics

  Aims to help people with penicillin allergy labels get safer, more effective antibiotics by using risk-based checks in outpatient settings.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11425328

• Preventing eczema-related allergies by strengthening infants' skin barrier

  This project will see if using a trilipid skin cream plus proactive mild topical steroids in infants with early dry skin or eczema lowers their chances of developing food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11418544

• Symptom-based questions to map how common food allergies are in the population

  A validated, symptom-based questionnaire will be tested to reliably estimate how common IgE-mediated food allergies are in both children and adults across the United States.

  NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-11412433

• SEAL: Stopping eczema and allergy by protecting the skin in infants

  A large clinical study in early infancy tests whether using a skin barrier cream together with a gentle anti-inflammatory cream can reduce the chance of developing food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11406152

• Food allergy differences by race/ethnicity from infancy to adolescence

  This study follows children with food allergy from infancy through adolescence to understand how race and ethnicity affect outcomes and management.

  NIH research Northwestern University · Chicago, United States · NIH-11397285

• Preventing food allergies by protecting babies' skin

  This trial tests whether starting a trilipid moisturizer plus early gentle topical steroids for babies with dry skin or early eczema can lower their chance of developing food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11393205

• Preventing food allergy by strengthening babies' skin barrier

  See if giving a trilipid emollient plus proactive topical steroid treatment to infants with very early dry skin or eczema can lower their chance of developing food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11392091

• Role of a special interferon-responsive T cell in allergies and asthma

  A study explores a unique interferon-responsive T cell type that may influence allergies and asthma, aiming to understand why some people become allergic and how this T cell subset could affect airway inflammation.

  NIH research San Diego Biomedical Research Institute · San Diego, United States · NIH-11389644

• Understanding why the gut barrier lets peanut allergic reactions happen

  A physician-scientist at UNC is studying why the lining of the gut becomes leaky in peanut allergy and how this may lead to worse reactions.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11380922

• Understanding why antibiotic allergy happens and how to improve care

  Researchers are exploring new ideas to understand and improve care for people who have antibiotic-related delayed allergic reactions.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11378721

• A mast cell receptor (MRGPRX2) linked to allergy and inflammation

  This project looks at whether a mast cell receptor called MRGPRX2 changes allergic reactions in people with asthma or inflammatory skin conditions.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11376336

• Childhood allergy and early-life environment linked to asthma and eczema care

  A study following children from infancy to understand how genes, the environment, and the skin and nasal bacteria affect asthma and atopic dermatitis.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11375189

• Children's Allergy and Asthma Data Hub

  A national data hub will pool and harmonize child allergy and asthma cohort data to help researchers discover ways to prevent asthma in kids.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11375082

• Better tests for cephalosporin (a common antibiotic) allergy

  This project tries new ways to tell whether someone who says they're allergic to cephalosporin antibiotics truly has a risky allergy.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11372125

• Antibiotic Allergy: Understanding Why Some Reactions Happen and How We Can Detect Them

  A Mayo Clinic team will study why certain antibiotics trigger dangerous allergy reactions and look for better ways to detect and understand these reactions.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11365846

• Parent-focused program to help remove penicillin allergy labels in kids

  A parent-friendly web tool helps families and their child’s pediatrician review and safely remove incorrect penicillin allergy labels.

  NIH research University of Connecticut Storrs · Storrs-Mansfield, United States · NIH-11353896

• Role of T cells in Alpha-Gal Allergy (AGS)

  This grant explores how T cells influence the allergic reaction to meat in people with Alpha-Gal syndrome.

  NIH research University of Virginia · Charlottesville, United States · NIH-11353668

• Viral and Host Factors in Infant and Child Allergy and Asthma

  This grant explores why some babies and young children develop asthma by studying how viruses, environment, and airway cells interact from birth.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11353460

• Childhood wheezing and its impact on thinking and behavior in young children

  A study follows preschool children with recurrent wheezing to understand how their illnesses and treatments may influence brain development and emotions.

  NIH research Washington University · Saint Louis, United States · NIH-11351026

• Safety and tolerability of a skin patch to treat peanut allergy

  A new skin patch designed to desensitize peanut allergy is being studied to see if it is safe and tolerable for people with peanut allergy.

  NIH research Moonlight Therapeutics, INC. · Marietta, UNITED STATES · NIH-11346046

• Children's Allergy and Asthma Data Hub (CADRE)

  This project builds a shared data hub that combines many childhood allergy and asthma birth-study records so researchers can find early-life factors that change a child's risk of asthma.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11345660

• Neural signals shaping specific lung immune cells to allergic airway disease

  A Johns Hopkins-led study looks at a special type of lung macrophage that, when guided by vagus nerve signals, promotes allergy-related inflammation in the airways.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11334290

• Better prevention and treatments for food allergies

  A coordinated program to develop and bring forward new ways to prevent and treat food allergies for children, teens, and adults.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11327316

• How microRNAs control allergy and asthma

  This work looks at tiny gene-regulating molecules called microRNAs to find molecular ways to reduce allergic inflammation in people with asthma.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11323869

Related topics

Quick answers

How many Allergy clinical trials are recruiting right now?

18, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (5 trials), France (4 trials), Denmark (2 trials), Hong Kong (1 trial), Finland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 4: 2, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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