Safety and tolerability of a skin patch to treat peanut allergy
Official title: Safety and Tolerability of TASIS-Peanut (Targeted Allergen Specific Immunotherapy within the Skin) patch for the Treatment of Peanut Allergy
Funded at Moonlight Therapeutics, INC. · NIH-11346046 · Data updated 2026-11-12
A new skin patch designed to desensitize peanut allergy is being studied to see if it is safe and tolerable for people with peanut allergy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Moonlight Therapeutics, INC. NIH-funded |
| Lab location | 1 site (Marietta, UNITED STATES) |
| Project start | June 2, 2025 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $999,927 |
| NIH project number | 5U44AI165328-03 |
| Project ID | NIH-11346046 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals with diagnosed peanut allergy across a wide age range, from children to adults, who can participate in a controlled patch application study.
✕Less likely to help
Some individuals may not tolerate the patch or may not experience a benefit in reducing reactions.
What this research studies
This grant supports a clinical approach using a patch applied to the skin to deliver tiny amounts of peanut allergen with a targeted immunotherapy approach. Researchers will assess safety and how well people tolerate the patch, aiming to minimize reactions and improve quality of life for individuals with peanut allergies. The study will involve participants who have peanut allergies and will monitor for adverse events, dose exposure, and potential immune responses in a controlled setting. If successful, this work could lay the groundwork for a convenient, non-dietary option to reduce allergy risk in everyday life.
Why it matters
Potential benefit: If successful, the patch could reduce allergic reactions from accidental peanut exposure and improve safety and confidence for people with peanut allergy.
How similar studies have gone: This approach builds on prior immunotherapy strategies delivered via the skin, with preliminary signals in safety and tolerability in similar patch-based methods.
Where this research is happening
-
Moonlight Therapeutics, INC.
Marietta, United States Active
Researchers
- Principal investigator: Patel, Samirkumar — Moonlight Therapeutics, INC.
- Study coordinator: Patel, Samirkumar
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.