Symptom-based questions to map how common food allergies are in the population
Official title: Refinement and validation of a symptom report-based food allergy prevalence questionnaire for population-based studies
Funded at Lurie Children's Hospital of Chicago · NIH-11412433 · Data updated 2026-11-12
A validated, symptom-based questionnaire will be tested to reliably estimate how common IgE-mediated food allergies are in both children and adults across the United States.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lurie Children's Hospital of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 10, 2025 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $1,626,709 |
| NIH project number | 5R01AI180079-02 |
| Project ID | NIH-11412433 on NIH RePORTER |
Who could benefit from this research
✓Could help
Any person (children or adults) in the US whose caregivers or themselves are seeking to understand potential food allergies or are participating in population surveillance
✕Less likely to help
People not involved in or affected by food allergies may not directly benefit from this study.
What this research studies
This project will create a set of survey questions with expert input to better identify true IgE-mediated food allergies. It will then compare answers from the questionnaire to clinical diagnoses to check accuracy. The goal is to make routine population surveillance of food allergies more practical and trustworthy for families and clinicians. The study will involve participants from diverse US communities to ensure the tool works widely. If successful, this questionnaire could support future prevention efforts and improved clinical management.
Why it matters
Potential benefit: Better, faster population estimates of food allergy prevalence could inform public health decisions and improve care for people with suspected allergies.
How similar studies have gone: Prior surveys exist but require validation against clinical diagnoses to ensure accuracy across populations.
Where this research is happening
-
Lurie Children's Hospital of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Gupta, Ruchi S — Lurie Children's Hospital of Chicago
- Study coordinator: Gupta, Ruchi S
Related research
Other NIH-funded projects on the same topics.
-
New Horizons in preventing and treating food allergy
A Johns Hopkins-led effort aims to advance how we prevent and treat food allergies across all ages by coordinating high-quality studies and developing better therapies.
-
New Horizons in Food Allergy Prevention and Treatment
A large, multi-site program at Johns Hopkins aims to advance prevention and treatment of food allergies across all ages.
-
Food allergy outcomes by race/ethnicity from infancy through adolescence
This study follows children with food allergies over time to understand how race and ethnicity relate to allergy management, outcomes, and quality of life.
-
Gut-brain links in food allergy responses
A research grant is exploring how signals between the gut and brain drive dangerous reactions to foods, with the goal of helping people with food allergies.
-
Targeting gut microbes to restore food-tolerance in adults
Aims to understand how gut bacteria and the lining of the gut interact to keep people with food allergies tolerant to what they eat.
-
Environment and early-life exposures shaping food allergy in children
This grant looks at how a child’s first year and their home environment may influence whether they develop food allergies, focusing on indoor exposures and microbes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.