Analyzing immune system issues in patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to create a national resource in Sweden for comprehensive immunological analyses of individuals with various forms of immune system dysregulation. It will establish a biobank of blood and fecal samples from patients with confirmed or suspected immune dysregulation, as well as healthy controls for comparison. The project will also develop a national database containing deep immunological data, treatment outcomes, and clinical information, accessible to researchers and clinicians involved in the study.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients of all ages seeking care or being referred for suspected immune dysregulation or with a known immune-mediated disease and failing to respond to standard therapy

Exclusion Criteria:

Healthy control individuals will be excluded on the basis of having a diagnosis of an immune mediated disorder, immunomodulatory treatment or current infection or cancer.

Where it's running

• Karolinska Institutet
  Stockholm, Sweden Recruiting

Study contacts

• Study coordinator: Petter Brodin, M.D., Ph.D
• Email: petter.brodin@ki.se
• Phone: 08 524 813 96

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• What the Mayo Clinic is learning from blood clot tests in allergic reactions

  This study tests whether real-time blood clotting markers can help understand and predict the severity of allergic reactions and anaphylaxis in patients 12 and older.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07905911

• ETHY-001 safety and activity in Thyroid Eye Disease (TED)

  This study tests ETHY-001 versus placebo to see if it is safe, tolerable, and shows activity in people with thyroid eye disease.

  Recruiting at 2 sites Phase 1 Ethyreal Bio, Inc. · Orland Park, Illinois and 2 other locations · NCT07885605

• Does having allergic parents raise the chance of bronchiolitis in babies by 12 months?

  We’re testing if infants with at least one allergic parent are more likely to have bronchiolitis by 12 months compared to infants whose parents have no allergies.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens, Picardie · NCT07832643

• CR-402 treatment for refractory autoimmune disease

  This study tests CRT-402, a CD19-targeted CAR-T therapy, in adults with active, treatment-resistant autoimmune diseases like SLE, systemic sclerosis, and inflammatory myopathy to see if it is safe and capable of helping control disease.

  Recruiting Phase 1/2 Myeloid Therapeutics · Nedlands, Western Australia · NCT07778446

• Music-4-MS: A 12-week music-based program to support thinking skills in people with MS

  A 12-week music-based program is tested to see if it helps cognitive function and mood in people living with multiple sclerosis.

  Recruiting University of Texas at Austin · Austin, Texas · NCT07759115

• ATG-201 in adults with autoimmune diseases

  This early, open-label study tests ATG-201 in adults with autoimmune diseases to see if it is safe and tolerable, and to get initial clues about how the body handles the drug and its effects.

  Recruiting Phase 1 Antengene Corporation · Bengbu, Anhui and 21 other locations · NCT07732309

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.