Children's Allergy and Asthma Data Hub
Official title: Children's Allergy and Asthma Data Repository (CADRE)
Funded at University of Wisconsin-Madison · NIH-11375082 · Data updated 2026-11-12
A national data hub will pool and harmonize child allergy and asthma cohort data to help researchers discover ways to prevent asthma in kids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | August 6, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $1,000,000 |
| NIH project number | 5U24AI179612-03 |
| Project ID | NIH-11375082 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children from birth to early childhood who are part of or eligible for existing allergy/asthma birth cohorts and data contributing centers.
✕Less likely to help
This grant does not involve direct patient treatment or enrollment; benefits come from research use of existing data.
What this research studies
This grant creates CADRE, a centralized repository for birth cohort data on allergy and asthma in children. Researchers will pool diverse datasets, harmonize variables, and provide user-friendly access and services to enable collaborative studies. The project builds on CREW experiences to expand data sharing while safeguarding data use and interpretation for future studies. By enabling easier access to large, diverse datasets, CADRE aims to accelerate discoveries that could prevent childhood asthma.
Why it matters
Potential benefit: If successful, CADRE could accelerate discoveries that lead to prevention strategies for childhood asthma and allergies.
How similar studies have gone: Data-sharing hubs and multi-cohort collaborations have demonstrated value in accelerating pediatric asthma research.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Gern, James E. — University of Wisconsin-Madison
- Study coordinator: Gern, James E.
Related research
Other NIH-funded projects on the same topics.
-
Childhood Allergy and the Neonatal Environment: Early Life Airways and Asthma
A long-term study following newborns to age 5 to understand how early-life nose and airway biology, immune development, and the environment influence asthma risk.
-
Role of a special interferon-responsive T cell in allergies and asthma
A study explores a unique interferon-responsive T cell type that may influence allergies and asthma, aiming to understand why some people become allergic and how this T cell subset could affect airway inflammation.
-
Viral and Host Factors in Infant and Child Allergy and Asthma
This grant explores why some babies and young children develop asthma by studying how viruses, environment, and airway cells interact from birth.
-
Children's Allergy and Asthma Data Hub (CADRE)
This project builds a shared data hub that combines many childhood allergy and asthma birth-study records so researchers can find early-life factors that change a child's risk of asthma.
-
How microRNAs control allergy and asthma
This work looks at tiny gene-regulating molecules called microRNAs to find molecular ways to reduce allergic inflammation in people with asthma.
-
A newly discovered interferon-responsive immune cell linked to allergies and asthma
Researchers are looking at whether a newly discovered interferon-responsive T cell helps protect people exposed to allergens from developing allergic reactions and asthma.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.