Optimal corticosteroid dosing for ARDS: short vs. prolonged therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a 3-by-2 factorial interventional trial in adults with ARDS to compare no steroids, low-dose regimens, and a medium-dose regimen, each given for 7 or 10 days. The study focuses on identifying how dose and duration of corticosteroids influence outcomes in early ARDS. Participants must be intubated for ARDS and not already on systemic steroids. The trial is led by National Taiwan University Hospital and conducted at a single center in Taipei.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ARDS (as defined by the Berlin definition) with an FiO₂ of 0.5 or higher
* On invasive mechanical ventilation
* Duration of intubation less than three days

Exclusion Criteria:

* Age less than 18 years
* Required to receive steroids or considered ineligible for steroids by the primary care team
* Receiving systemic steroid therapy
* Uncontrolled gastrointestinal bleeding
* Uncontrolled infeciotn

Where it's running

• National Taiwan University Hospital
  Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Sheng-Yuan Ruan, MD, PhD
• Email: syruan@ntu.edu.tw
• Phone: 886223123456

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• How torso tilt and ventilator PEEP affect lung opening in ARDS

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.