Using a paravertebral block during thoracic (VATS/RATS) surgery to reduce postoperative complications

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study with retrospective and prospective components conducted at Tongji Hospital campuses, focusing on patients undergoing thoracic operations such as wedge resection, segmentectomy, lobectomy, or mediastinal surgery. Retrospectively, prior cases in which an intraoperative paravertebral block (PVB) was used will be analyzed for associations with postoperative complications. Prospectively, perioperative biomarkers (including MMP3, neutrophils, leukocytes, PCT, CRP) and clinical measures (pain and cough scores, time to first flatus and defecation) will be collected, with 30-day follow-up for postoperative complications. The study will correlate biochemical markers with clinical outcomes to explore potential prognostic relationships.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Male or female participants aged 18 years or older.
2. Scheduled to undergo thoracic surgery via Video-Assisted Thoracoscopic Surgery (VATS) or Robotic-Assisted Thoracoscopic Surgery (RATS), including wedge resection, segmentectomy, lobectomy, or mediastinal surgery.
3. Signed informed consent obtained prior to study participation. -

Exclusion Criteria:

1. Patients who refuse to provide informed consent.
2. Anesthesiologists who have not received training in ultrasound-guided paravertebral block (PVB-US).
3. History of ipsilateral thoracic surgery.
4. Conversion to open thoracotomy during the procedure.
5. Patients who did not complete the scheduled surgery due to disease progression or medical reasons.
6. Patients who are lost to follow-up or refuse postoperative follow-up. -

Where it's running

• Tongji Medical College of HUST: Huazhong University of Science and Technology Tongji Medical College Tongji Hospital
  Wuhan, Hubei, China Recruiting

Study contacts

• Principal investigator: Zhang qin Zhang — Huazhong keji daxue tongji yixue yuan fushu tongji yiyuan
• Study coordinator: Guo jiateng Guo
• Email: 18737552580@163.com
• Phone: 18737552580

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.