Condition

Ventilator-Induced Lung Injury clinical trials and research

• 12Clinical trials
• 5NIH research projects
• 8Countries

Newest Ventilator-Induced Lung Injury clinical trials

All recruiting trials (12)

• How different ventilator settings affect lung energy during gallbladder surgery

  This study tests whether two ventilator modes (VCV and PRVC) deliver different amounts of energy to the lungs in adults undergoing laparoscopic gallbladder removal.

  Recruiting Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Yenimahalle, Ankara · NCT07670494

• Height measurement methods to guide ventilator settings in ARDS

  We’re testing whether more precise height measurements change how researchers set lung-protective tidal volumes in adults with ARDS who are on a ventilator.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07595926

• Measuring breathing effort before and after removing the breathing tube

  This will test a new electrical impedance method to measure breathing effort in adults on ventilators as they try breathing on their own and after the breathing tube is removed.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT07017608

• Prognostic model for Acute Respiratory Distress Syndrome using Electrical Impedance Tomography

  This study is trying to see if a new way of measuring lung function can help doctors predict how well patients with Acute Respiratory Distress Syndrome (ARDS) will do and tailor their treatment accordingly.

  Recruiting at 4 sites Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Guangzhou, Guangdong and 3 other locations · NCT06967207

• Using Electrical Impedance Tomography to Optimize Ventilator Settings in Patients with Severe Breathing Problems

  This study is trying to see if using a special imaging technique can help set ventilators better for patients with severe breathing problems like acute respiratory failure.

  Recruiting Mahidol University · Bangkok · NCT06936618

• Inspiratory-effort–targeted pressure support for adults on ventilators

  This study will test whether using inspiratory effort measured by the pressure muscle index to set pressure support helps adults with acute hypoxic respiratory failure on ventilators have better outcomes than the usual tidal volume and respiratory rate approach.

  Recruiting Capital Medical University · Beijing, Beijing Municipality · NCT06526598

• Understanding lung injury caused by ventilators in elderly patients

  This study looks at how age affects lung damage from ventilators in older patients to see if longer use of these machines harms their lungs more.

  Recruiting Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai · NCT06367946

• Open lung extubation strategy for patients after abdominal surgery

  This study is testing if a new way to take patients off breathing machines after abdominal surgery can reduce lung problems compared to the usual method.

  Recruiting at 3 sites Centre hospitalier de l'Université de Montréal (CHUM) · Vancouver, British Columbia and 4 other locations · NCT06296173

• Assessing Diaphragm Activity and Breathing Mechanics During NAVA Ventilation

  This study is testing if a special type of breathing support called NAVA can help lung transplant patients breathe better and protect their lungs while they recover in the ICU.

  Recruiting University of Padova · Padova, Italy · NCT05689476

• Measuring lung mechanics in patients on mechanical ventilation

  This study is testing how mechanical ventilation affects lung function in patients with breathing problems to help improve their care and reduce lung injury.

  Recruiting Göteborg University · Gothenburg, Västra Götaland County · NCT04484727

• Using a decision support tool to improve ventilation in children with ARDS

  This study is trying out a new tool to help doctors manage breathing machines better for kids with serious lung problems to see if it can improve their recovery.

  Recruiting at 6 sites Children's Hospital Los Angeles · Chicago, Illinois and 7 other locations · NCT04068012

• New ultrasound tool to measure lung strain in ICU patients

  This study is testing a new ultrasound tool to see if it can help doctors measure lung strain in ICU patients on ventilators to prevent lung injuries.

  Recruiting Centre hospitalier de l'Université de Montréal (CHUM) · Montreal, Quebec · NCT03405779

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How high-pressure ventilators can damage human lungs

  Researchers will compare high- versus low-pressure ventilation on donated human lungs to learn which cells and molecules get hurt in people with respiratory failure.

  NIH research Stanford University · Stanford, United States · NIH-11324205

• Protecting the lung lining during ventilator-related injury

  This work develops ways to keep the lung's barrier intact in people with ARDS who need mechanical ventilation.

  NIH research University of Vermont & St Agric College · Burlington, United States · NIH-11323092

• Understanding how to protect lung tissue during mechanical ventilation in patients with severe respiratory distress

  This study is looking at how using a ventilator can sometimes hurt the lungs of people with acute respiratory distress syndrome (ARDS), and it aims to find the best ways to help their lungs heal while still providing the support they need.

  NIH research University of Vermont & St Agric College · Burlington, United States · NIH-11077693

• Mapping how ventilator use can harm lungs

  This study is looking at how using a ventilator can affect the lungs of people who develop acute respiratory distress syndrome (ARDS), with the goal of finding better treatments for those who experience lung injury from high-pressure ventilation.

  NIH research Stanford University · Stanford, United States · NIH-11047671

• Finding ways to prevent lung injury caused by ventilators in patients with severe respiratory issues.

  This study is looking at ways to make breathing machines safer for people with acute respiratory distress syndrome (ARDS) by creating a system that helps doctors adjust the machines to better fit each patient's needs, which could lead to better recovery.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11003305

Related topics

Quick answers

How many Ventilator-Induced Lung Injury clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in Canada (4 trials), China (3 trials), Italy (2 trials), Thailand (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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