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Clinical trials and research at Henry Ford Health System
As of November 12, 2026, Find a Trial lists 42 clinical trials run by Henry Ford Health System that are recruiting, in United States. By phase: Phase 2 (8), Phase 4 (5), Phase 1 (4), Phase 2/3 (1). There are also 34 NIH-funded research projects at this institution, with $20.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 42Clinical trials
- 34NIH research projects
- 1Country
Newest trials
All recruiting trials (42)
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Can Gleolan help highlight kidney tumors during partial nephrectomy?
This study tests whether giving Gleolan before kidney surgery helps fluorescence identify cancer tissue in adults with suspected kidney cancer undergoing partial nephrectomy.
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See how well ICG fluorescence can show knee tissue blood flow during arthroscopy
This study tests whether injecting a dye called ICG can help doctors see blood flow in knee tissues during arthroscopic knee surgery, including different ACL tear severities.
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Long-acting local pain medicine after knee replacement
This study tests whether a new extended-release pain medicine (Zynrelef) given around the knee during total knee replacement can reduce pain after surgery better or as well as standard injections or nerve blocks.
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Can blood and physical tests before transplant predict non-relapse mortality
This study tests whether pre-transplant blood markers and physical tests can predict non-relapse mortality in adults undergoing stem cell therapy.
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Multimodal Pain Plan to Cut Opioids After Hip Replacement
This study tests whether a multimodal pain regimen with a printed opioid prescription (instead of pharmacy-direct dispensing) can control pain after hip replacement while reducing opioid use.
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Peanut intake and liver health in adults with MASLD
This study tests whether adding peanuts to daily meals for 12 weeks can improve liver markers and metabolic health in adults with MASLD.
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Comparing targeted Y-90 radioembolization with focused external SBRT for liver cancer
This trial tests whether Y-90 transarterial radioembolization or focused stereotactic body radiation (SBRT) better controls hepatocellular carcinoma lesions in adults eligible for either treatment.
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Michigan experience using the Tigertriever device to remove brain clots
This project tries to see if the Tigertriever device safely and effectively removes large brain clots in adults who have an ischemic stroke within 8 hours of symptom onset.
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Comparison of radical prostatectomy and precision prostatectomy for men with low- or intermediate-risk prostate cancer
This trial tests whether precision prostatectomy preserves sexual function and bladder control better than radical prostatectomy for men with low- or intermediate-risk prostate cancer.
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Sacituzumab govitecan with atezolizumab or durvalumab as maintenance for extensive-stage small cell lung cancer
This study tests whether adding sacituzumab govitecan to ongoing atezolizumab or durvalumab can better control tumors in adults with extensive-stage small cell lung cancer after initial platinum-based chemotherapy.
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Early restorative sleep treatment after an emergency department visit
This trial will try virtual cognitive behavioral therapy for insomnia and nightmares soon after an assault-related emergency visit to see if it improves sleep and reduces PTSD symptoms.
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Using genetic scores to guide beta-blocker treatment for heart failure with mildly reduced ejection fraction
This study will test whether a genetic (polygenic) score can help predict which adults with heart failure and an ejection fraction of 41–50% will benefit from beta-blocker (metoprolol) treatment.
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Ketorolac for pain control after hip arthroscopy
This will test whether ketorolac can control pain and reduce opioid use after hip arthroscopy in adults.
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Fluorescence detection of upper tract urothelial carcinoma with oral 5-ALA during ureteroscopy
This study tests whether taking oral 5-ALA before ureteroscopy helps surgeons use blue-light fluorescence to see and remove upper tract urothelial tumors in adults having ureteroscopic tumor resection.
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Post-incision antimicrobial washes to reduce C. acnes after shoulder replacement
This trial will test whether applying different antimicrobial washes after the first incision lowers C. acnes growth in adults having primary shoulder replacement.
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Determining the best time to measure cervical length during fetal anatomy surveys
This study is testing the best time to measure cervical length during ultrasounds in pregnant people to see if it makes a difference in accuracy, while also comparing two types of ultrasound images.
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Improving sleep for night shift workers using a personalized mobile app
This study is testing a personalized mobile app to see if it can help night shift workers get better sleep.
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Using multiple wearable sensors to track sleep in nightshift workers
This project will test whether combining wearable sensors and machine learning can more accurately detect daytime sleep in nightshift workers.
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Cooling device to preserve taste during radiation for head and neck cancer
This study is testing a cooling device to see if it can help people with advanced throat cancer keep their sense of taste while they undergo radiation and chemotherapy.
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Connecting jail release data with health records for suicide prevention
This study is testing if linking jail release records with health records can help people get better mental health support after leaving jail to prevent suicide.
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Mindfulness-based sleep program for pregnant women to prevent depression
This study is testing a mindfulness-based sleep program to see if it can help pregnant women with insomnia reduce their risk of depression.
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Helping people with alcohol-related liver disease find and start alcohol treatment
This trial tests whether a tailored web app plus a follow-up coaching bundle can help people with alcohol-related liver disease start and stay in alcohol-use treatment.
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Using a laser to reduce post-inflammatory hyperpigmentation
This study is testing whether a special laser treatment can help reduce dark spots on the skin caused by inflammation in people with darker skin types.
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Improving Future Thinking Among Mothers
This study is testing a new way to help mothers from low-resource communities think more about the future to see if it can improve their parenting and strengthen their relationship with their children.
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Nonopioid pain management after surgery for traumatic fractures
This study tests whether a nonopioid pain management plan can help adults recovering from surgery for traumatic fractures feel better and have fewer side effects than using opioids.
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Using portable air cleaners to improve heart failure outcomes
This study is testing if giving portable air cleaners to heart failure patients when they leave the hospital can help them feel better by reducing their exposure to air pollution.
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Combining sacituzumab govitecan with capecitabine for advanced gastrointestinal cancers
This study is testing if combining two cancer treatments, sacituzumab govitecan and capecitabine, can help people with advanced gastrointestinal cancers that haven't improved with standard treatments.
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Improving recovery after ACL surgery with virtual therapy
This study is testing if a virtual therapy program can help people recover better and get back to sports after ACL surgery compared to just regular care.
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Predicting acute graft versus host disease using blood samples
This study is trying to find specific markers in blood samples that can help predict if patients over 18 will develop severe acute graft versus host disease after receiving a stem cell transplant.
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Gene therapy combined with radiotherapy for brain tumors
This study is testing a new gene therapy combined with targeted radiation to see if it can safely help people with recurrent high-grade brain tumors.
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Using budesonide to prevent engraftment syndrome after stem cell transplantation
This study is testing if the medication budesonide can help prevent fever and other symptoms after stem cell transplants in patients with blood cancers.
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Bioinductive patch for repairing rotator cuff tears
This study is testing if adding a special patch during surgery can help people with rotator cuff tears heal better than just standard surgery alone.
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Modeling temperature changes during HIPEC surgery
This study is testing a new computer model to see how temperature changes during HIPEC surgery for abdominal cancer, aiming to help doctors keep patients safe and improve treatment.
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Investigating how sleep reactivity affects shift work disorder
This study is testing if how sensitive your sleep is can cause Shift Work Disorder and if treating sleep issues with therapy can help people who still have problems after adjusting their sleep schedule.
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Combining laser treatment and radiosurgery for spinal tumors
This study is testing if using both laser treatment and targeted radiation can help people with spinal tumors feel better and improve their quality of life compared to just using radiation alone.
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Combining post-transplant cyclophosphamide with uhCG/EGF for preventing Graft Versus Host Disease
This study is testing if a new combination of medications can help prevent Graft Versus Host Disease in patients with blood cancers who are getting stem cell transplants from unrelated donors.
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Investigating gut bacteria changes during stem cell transplant
This study is trying to see how antibiotics used during stem cell transplants affect gut bacteria and whether these changes influence complications like graft-versus-host disease and relapse rates in patients.
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Using Tranexamic Acid to Treat Skin Pigmentation Disorders
This study is testing if tranexamic acid can help people with skin pigmentation disorders like lichen planus pigmentosus and erythema dyschromicum perstans feel better and improve their skin color.
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Using azacitidine to improve donor chimerism in patients with myeloid malignancies after stem cell transplant
This study is testing if the drug azacitidine can help patients with acute myeloid leukemia or myelodysplastic syndromes maintain healthy donor cells after a stem cell transplant without causing new complications.
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HLA-Haploidentical Stem Cell Transplant with Cyclophosphamide and Bortezomib
This study is testing a new stem cell transplant method for patients with blood cancers who don't have a matched donor, using special medications to help their bodies accept the transplant and recover better.
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Nonopioid pain management after shoulder surgery
This study tests whether a nonopioid pain management approach can help adults recovering from shoulder surgery feel less pain compared to the usual opioid treatment.
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Testing a new implant for treating tennis elbow
This study is testing a new patch to see if it can help people with tennis elbow heal better after surgery compared to just having the standard surgery alone.
NIH-funded research (34)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Long-Term Effectiveness of Uterine-Sparing Fibroid Treatments for Black and White Women
This project follows real patients who had fibroid treatments to see how well symptoms and quality of life hold up over up to 10 years.
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Multimorbid pediatric atopic and airway diseases: prenatal exposures and placental epigenetics
This study follows a group of children to understand how early environmental exposures before birth and placental biology relate to multiple allergic and airway conditions in kids.
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Understanding how vitamin D receptors control skin barrier function
This project looks at how vitamin D receptor signals in the skin influence the barrier that protects us from infection and inflammation.
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Understanding childhood allergies and breathing problems, and how early life factors play a role
This project continues to follow children to understand how allergies and breathing problems develop and how factors before birth might influence them.
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Why prostate cancer becomes resistant to anti-androgen drugs
This work looks at whether blocking a protein called Tribbles 2 can help men whose prostate cancer stopped responding to anti-androgen drugs regain sensitivity to treatment.
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Blood DNA methylation test to detect and track glioma
This project uses a small blood sample to look for tumor DNA changes that could find and follow glioma in people with brain tumors.
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Understanding cancer causes and prevention methods
This study is looking for people to help us understand how different health habits and behaviors might affect cancer risk, so if you're interested in sharing your experiences and providing some samples, you can help us find better ways to prevent cancer!
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Making online cognitive behavioral therapy for insomnia easier to use and stick with
An improved online CBT program aims to help adults with insomnia complete treatment and follow key sleep‑improving steps, especially people with lower income or low health literacy.
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Sleep reactivity and night-shift sleep problems
This project looks at whether a person’s tendency for sleep to be easily disturbed (sleep reactivity) helps explain excessive sleepiness and insomnia in night-shift workers.
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Long-Term Results for Uterine-Sparing Fibroid Care
This project aims to understand the long-term health and quality of life for women who have received treatments for uterine fibroids that allow them to keep their uterus.
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Understanding Skin Barrier Differences
This project explores how our skin's protective barrier and vitamin D production adapt to different environments, especially looking at differences between people of European and African descent.
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Improving language exposure for infants in neonatal intensive care units
This study is all about helping babies in the NICU by encouraging parents and doctors to talk to them more in a special way that supports their language development, making it easier for these little ones to grow and learn.
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Using exosomes from healthy brain cells to improve memory in older diabetic rats
This study is looking at how tiny particles from brain cells might help improve thinking and memory in older rats with diabetes, and it hopes to find ways to boost brain health for older people dealing with similar issues.
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Investigating the role of Tribbles 2 in prostate cancer after anti-androgen therapy
This study is looking at how prostate cancer cells stop responding to treatments like enzalutamide, and it aims to find new ways to tackle these tough cells by focusing on a protein called Tribbles 2, which might help them grow and resist treatment.
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Using blood tests to improve detection and monitoring of glioma
This study is looking at how analyzing DNA from your blood can help doctors better detect and track brain tumors called gliomas, making it easier to monitor your condition without needing invasive tests.
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Evaluating long-term outcomes of treatments for uterine fibroids
This study is looking at how well different treatments for fibroids work over time, especially for Black women who often face more challenges with this condition, to help improve their care and quality of life.
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Improving digital therapy for insomnia to help more people stick with treatment
This study is testing a new and improved online therapy for insomnia to help more people, especially those from different backgrounds, stick with their treatment and get better sleep.
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Understanding how sleep reactivity affects shift work disorder
This study is looking into why nightshift workers often feel really tired and have trouble sleeping, with the goal of finding better ways to help them feel better and stay healthy, rather than just giving them medication to manage the symptoms.
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Helping adolescents from underserved communities make better decisions to avoid substance misuse
This study is looking for ways to help teenagers in low-income neighborhoods avoid using drugs or alcohol by improving their decision-making skills and memory, especially for those who have faced tough times in childhood.
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Helping expecting moms with insomnia and stress management
This study is looking to help pregnant women in their third trimester who are having trouble sleeping by teaching them mindfulness techniques and sleep strategies to reduce stress and improve their sleep quality.
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Improving bone health by targeting specific receptors in bone cells
This study is looking at how bone cells react to physical stress and how we can improve this response to help prevent osteoporosis and fractures in older adults by focusing on a specific receptor in the cells.
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Understanding how cells communicate in pancreatic cancer
This study is looking at how certain cells in pancreatic cancer work together and affect the immune system, with the goal of finding new ways to improve treatment for patients with this type of cancer.
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Using gold nanoparticles to enhance radiotherapy for triple negative breast cancer
This study is looking at how tiny gold particles can make radiation treatment work better for people with triple negative breast cancer by boosting the immune system's ability to fight the cancer.
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Investigating how astrocytes influence the risk of developing cerebral adrenoleukodystrophy.
This study is looking at how a specific type of brain cell called astrocytes behaves in people with X-linked adrenoleukodystrophy (X-ALD) to find clues that could help improve treatment and management of the condition.
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Understanding how skin adapts to different environments and its role in vitamin D production
This study is looking at how a protein called involucrin helps our skin adapt to different environments and how it affects skin health and immune responses, which could help people with conditions like atopic dermatitis understand their skin better and find ways to support it.
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Training postdoctoral fellows in mental health services within health systems
This program is designed to help new researchers learn how to improve mental health care by using data from health systems that care for millions of patients, so they can work together with experts to find better ways to support people’s mental health.
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Understanding how cells communicate in pancreatic cancer
This study is looking at how certain cells in pancreatic cancer work together and communicate, which could help us find new ways to treat the disease and improve patient care.
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How calorie restriction affects immune cells to fight ovarian cancer
This study is looking at how eating fewer calories might help your immune system fight epithelial ovarian cancer better by changing the way certain immune cells work, and it's aimed at finding new dietary tips that could make cancer treatments more effective for patients like you.
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Understanding alcohol use after weight loss surgery
This study is looking into why some people start drinking alcohol again after having weight loss surgery, focusing on how their feelings and eating habits might play a role, and it aims to help create better support for those patients.
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Using prenatal yoga to help prevent postpartum depression
This study is testing a virtual prenatal yoga program to see if it can help prevent postpartum depression in women at higher risk, especially those from diverse backgrounds, by promoting mindfulness and physical activity.
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Helping parents make better long-term choices to improve child mental health.
This study is looking at how parents in underserved communities make choices about their parenting, especially when they might prefer quick fixes instead of long-term benefits, and it aims to help them find better ways to nurture their kids to improve their mental health.
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Exosomes from Schwann cells may help improve nerve function in diabetic mice
This study is looking at how tiny particles from special cells can help improve nerve health in mice with diabetic nerve damage, and it hopes to show that these particles can make nerves work better without changing blood sugar levels.
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Helping parents in treatment for substance use improve their parenting skills
This study is looking at parents in treatment for substance use who might struggle with using tough parenting methods, and it aims to help them focus on long-term benefits for their kids instead of just immediate rewards, so they can become more positive and supportive parents.
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Using technology to help reduce alcohol use after weight loss surgery
This study is testing a helpful program for people who have had weight loss surgery and might be dealing with alcohol use issues, using a computer-based tool and supportive text messages to make it easier for them to manage their drinking.
Quick answers
How many clinical trials run by Henry Ford Health System are recruiting right now?
42, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 8, Phase 4: 5, Phase 1: 4, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.