Can blood and physical tests before transplant predict non-relapse mortality
Official title: BIO-FUNCTION for NRM Prediction in SCTCT: Assessing Biological and Functional Reserve to Predict Non-Relapse Mortality in Stem Cell Transplant and Cell Therapy
Run by Henry Ford Health System · NCT07769151 · Data updated 2026-11-12
This study tests whether pre-transplant blood markers and physical tests can predict non-relapse mortality in adults undergoing stem cell therapy.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 124 (estimated) |
| Sponsor | Henry Ford Health System Academic / other |
| Locations | 1 site (Detroit, Michigan) |
| Status | Recruiting |
| Started | October 1, 2026 |
| Main results expected | December 30, 2030 |
| Study ends | December 30, 2031 |
| Registry record updated | October 19, 2026 |
| Trial ID | NCT07769151 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 years who are planned to receive stem cell transplantation or cellular therapy at Henry Ford Health System.
✕Probably not a fit
Individuals not showing a predictive signal in baseline tests or those with factors outside the studied parameters may not benefit from risk stratification.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study looks for signals in blood tests, including CXCL9, and physical assessments conducted before stem cell transplant or cell therapy to see if they can predict non-relapse mortality. Participants are adults planned for SCTCT and will be observed to identify potential predictors. The analysis aims to identify factors that could help stratify risk and guide clinical decisions.
Why it matters
Potential benefit: If successful, the findings could help clinicians identify high-risk patients early and tailor monitoring or treatment strategies accordingly.
How similar studies have gone: Prior research in related transplant settings has identified biomarkers and clinical tests that correlate with outcomes, but this specific combination before SCTCT is novel or has limited prior evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients \>18 year old * patients planned for SCTCT Exclusion Criteria: * Pregnancy * prisoners * Patients with a serious medical or psychiatric illness likely to interfere with participation in this clinical study
Where it's running
-
Henry Ford Health
Detroit, Michigan, United States Recruiting
Study contacts
- Study coordinator: Shatha Farhan, MD
- Email: sfarhan1@hfhs.org
- Phone: 3137133910
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.