Clinical trial Recruiting at 1 site Observational Ages 18 and up

Can blood and physical tests before transplant predict non-relapse mortality

Official title: BIO-FUNCTION for NRM Prediction in SCTCT: Assessing Biological and Functional Reserve to Predict Non-Relapse Mortality in Stem Cell Transplant and Cell Therapy

Run by Henry Ford Health System · NCT07769151 · Data updated 2026-11-12

This study tests whether pre-transplant blood markers and physical tests can predict non-relapse mortality in adults undergoing stem cell therapy.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment124 (estimated)
SponsorHenry Ford Health System
Academic / other
Locations1 site (Detroit, Michigan)
StatusRecruiting
StartedOctober 1, 2026
Main results expectedDecember 30, 2030
Study endsDecember 30, 2031
Registry record updatedOctober 19, 2026
Trial IDNCT07769151 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 years who are planned to receive stem cell transplantation or cellular therapy at Henry Ford Health System.

Probably not a fit

Individuals not showing a predictive signal in baseline tests or those with factors outside the studied parameters may not benefit from risk stratification.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study looks for signals in blood tests, including CXCL9, and physical assessments conducted before stem cell transplant or cell therapy to see if they can predict non-relapse mortality. Participants are adults planned for SCTCT and will be observed to identify potential predictors. The analysis aims to identify factors that could help stratify risk and guide clinical decisions.

Why it matters

Potential benefit: If successful, the findings could help clinicians identify high-risk patients early and tailor monitoring or treatment strategies accordingly.

How similar studies have gone: Prior research in related transplant settings has identified biomarkers and clinical tests that correlate with outcomes, but this specific combination before SCTCT is novel or has limited prior evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients \>18 year old
* patients planned for SCTCT

Exclusion Criteria:

* Pregnancy
* prisoners
* Patients with a serious medical or psychiatric illness likely to interfere with participation in this clinical study

Where it's running

  • Henry Ford Health
    Detroit, Michigan, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.