Ketorolac for pain control after hip arthroscopy
Efficacy of Ketorolac for Postoperative Pain Management in Hip Arthroscopy: A Prospective Randomized Controlled Trial
This will test whether ketorolac can control pain and reduce opioid use after hip arthroscopy in adults.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 89 Years |
| Sex | All |
| Sponsor | Henry Ford Health System Academic / other |
| Locations | 1 site (Detroit, Michigan) |
| Trial ID | NCT07037888 on ClinicalTrials.gov |
What this trial studies
This is a prospective, double-blinded, randomized trial at Henry Ford Health in Detroit comparing postoperative ketorolac to the standard opioid-based pain regimen in adults undergoing hip arthroscopy for femoroacetabular impingement. Participants are randomly assigned to receive ketorolac or the usual hydrocodone-acetaminophen protocol with blinding of patients and study staff. The trial measures postoperative pain scores and total opioid consumption, and excludes patients with NSAID contraindications, chronic opioid use, substance use disorder, or inability to be discharged the same day. Enrollment is limited to English-speaking adults able to consent and recover locally at the study center.
Who should consider this trial
Good fit: Adults over 18 with femoroacetabular impingement scheduled for hip arthroscopy with the enrolling surgeon at Henry Ford who can consent, speak English, are eligible for NSAID use, are not chronic opioid users, and are expected to be discharged the same day.
Not a fit: Patients with NSAID contraindications, a history of substance use disorder, chronic opioid use, inability to stop interacting medications, or those not discharged same day are unlikely to qualify or benefit from this protocol.
Why it matters
Potential benefit: If successful, the approach could provide effective pain relief while lowering postoperative opioid use and opioid-related side effects.
How similar studies have performed: Ketorolac and other NSAIDs have reduced opioid requirements after many types of surgery, but randomized data specifically for hip arthroscopy are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing hip arthroscopy over the age of 18 with Dr. T. Sean Lynch * Diagnosis of femoroacetabular impingement (FAI) Exclusion Criteria: * Patients with inability to consent and/or do not speak English * Patients with conditions contraindicated with NSAIDs (medication allergy, peptic ulcer disease, bleeding diathesis, and renal disease) * Patients with history of drug and alcohol use disorder * Patients with chronic analgesia (filled two opioid prescriptions within 6 months of the surgery) * Patients with psychotropic medication usage * Patients who take pentoxifylline, probonecid, aspirin, and/or NSAIDs who cannot stop taking it for the study * Patients who are not discharged same day after surgery
Where this trial is running
Detroit, Michigan
- Henry Ford Health — Detroit, Michigan, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.