Long-Term Results for Uterine-Sparing Fibroid Care

Long Term Effectiveness of Uterine Sparing Fibroid Treatments

NIH-funded research Henry Ford Health System · NIH-11158658

This project aims to understand the long-term health and quality of life for women who have received treatments for uterine fibroids that allow them to keep their uterus.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHenry Ford Health System NIH-funded
Lab location1 site (Detroit, United States)
Project IDNIH-11158658 on NIH RePORTER

What this research studies

Uterine fibroids are very common, especially among Black women, and often lead to hysterectomies, causing heavy bleeding, pain, and other issues. While there are several options to treat fibroids without removing the uterus, like myomectomy or uterine artery embolization, we don't have enough information about how well these treatments work over many years. This project will follow women who have already had these uterine-sparing treatments for up to 10 years, gathering important details about their symptoms, quality of life, and any further treatments needed. The goal is to provide better guidance for women and their doctors when choosing the best fibroid treatment.

Who could benefit from this research

Good fit: This project is for women who have previously participated in the COMPARE-UF or ULTRA registries and have undergone uterine-sparing fibroid treatments.

Not a fit: Patients who have not had uterine fibroids or who have not received uterine-sparing treatments would not directly benefit from this specific follow-up project.

Why it matters

Potential benefit: If successful, this work could help women and their doctors make more informed decisions about uterine fibroid treatments, potentially improving long-term health outcomes and quality of life.

How similar studies have performed: Prior studies on uterine fibroid treatments have had limited follow-up time, making this project novel in its focus on long-term outcomes.

Where this research is happening

Detroit, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.