Modeling temperature changes during HIPEC surgery
Development of a Computational, Thermodynamic Model of Intraabdominal Hyperthermia in Humans Undergoing HIPEC
Henry Ford Health System · NCT05426928
This study is testing a new computer model to see how temperature changes during HIPEC surgery for abdominal cancer, aiming to help doctors keep patients safe and improve treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Henry Ford Health System (other) |
| Drugs / interventions | Chemotherapy |
| Locations | 1 site (Detroit, Michigan) |
| Trial ID | NCT05426928 on ClinicalTrials.gov |
What this trial studies
This project aims to develop and validate a computational thermodynamic model to predict temperature changes in patients undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for abdominal cancers. By collecting real-world data from patients, the study will incorporate various factors such as patient demographics, anesthetic methods, and circulatory impacts to understand temperature variations during the procedure. The goal is to enhance the safety and effectiveness of HIPEC by providing clinicians with better predictive tools for managing body temperatures during treatment.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are scheduled to undergo HIPEC surgery for abdominal cancer.
Not a fit: Patients who are pregnant, minors, or have diseases not suitable for HIPEC treatment will not benefit from this study.
Why it matters
Potential benefit: If successful, this model could lead to improved safety and efficacy of HIPEC treatments for patients with peritoneal surface malignancies.
How similar studies have performed: While previous studies have explored abdominal hyperthermia, this specific approach to modeling temperature changes during HIPEC in humans is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (at least 18 years or older) * Scheduled to undergo HIPEC surgery for abdominal cancer at HFH-Main Exclusion Criteria: * Pregnant females * Minors * Disease not amenable for treatment with HIPEC after surgical examination.
Where this trial is running
Detroit, Michigan
- Katherine Nowak — Detroit, Michigan, United States (RECRUITING)
Study contacts
- Principal investigator: Carlos Guerra, MD — Staff Anesthesiologist
- Study coordinator: Katherine Nowak, PhD
- Email: knowak2@hfhs.org
- Phone: 313-771-7128
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: HIPEC, Predictive model, Intraabdominal hyperthermia, Thermodynamics