Modeling temperature changes during HIPEC surgery
Official title: Development of a Computational, Thermodynamic Model of Intraabdominal Hyperthermia in Humans Undergoing HIPEC
Run by Henry Ford Health System · NCT05426928 · Data updated 2026-11-12
This study is testing a new computer model to see how temperature changes during HIPEC surgery for abdominal cancer, aiming to help doctors keep patients safe and improve treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Henry Ford Health System Academic / other |
| Drugs / interventions | Chemotherapy |
| Locations | 1 site (Detroit, Michigan) |
| Status | Recruiting |
| Started | September 22, 2022 |
| Main results expected | December 30, 2026 |
| Study ends | March 31, 2027 |
| Registry record updated | October 20, 2025 |
| Trial ID | NCT05426928 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who are scheduled to undergo HIPEC surgery for abdominal cancer.
✕Probably not a fit
Patients who are pregnant, minors, or have diseases not suitable for HIPEC treatment will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to develop and validate a computational thermodynamic model to predict temperature changes in patients undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for abdominal cancers. By collecting real-world data from patients, the study will incorporate various factors such as patient demographics, anesthetic methods, and circulatory impacts to understand temperature variations during the procedure. The goal is to enhance the safety and effectiveness of HIPEC by providing clinicians with better predictive tools for managing body temperatures during treatment.
Why it matters
Potential benefit: If successful, this model could lead to improved safety and efficacy of HIPEC treatments for patients with peritoneal surface malignancies.
How similar studies have gone: While previous studies have explored abdominal hyperthermia, this specific approach to modeling temperature changes during HIPEC in humans is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (at least 18 years or older) * Scheduled to undergo HIPEC surgery for abdominal cancer at HFH-Main Exclusion Criteria: * Pregnant females * Minors * Disease not amenable for treatment with HIPEC after surgical examination.
Where it's running
-
Katherine Nowak
Detroit, Michigan, United States Recruiting
Study contacts
- Principal investigator: Carlos Guerra, MD — Staff Anesthesiologist
- Study coordinator: Katherine Nowak, PhD
- Email: knowak2@hfhs.org
- Phone: 313-771-7128
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.