Clinical trial Recruiting at 1 site Observational Ages 18 and up

Modeling temperature changes during HIPEC surgery

Official title: Development of a Computational, Thermodynamic Model of Intraabdominal Hyperthermia in Humans Undergoing HIPEC

Run by Henry Ford Health System · NCT05426928 · Data updated 2026-11-12

This study is testing a new computer model to see how temperature changes during HIPEC surgery for abdominal cancer, aiming to help doctors keep patients safe and improve treatment.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorHenry Ford Health System
Academic / other
Drugs / interventionsChemotherapy
Locations1 site (Detroit, Michigan)
StatusRecruiting
StartedSeptember 22, 2022
Main results expectedDecember 30, 2026
Study endsMarch 31, 2027
Registry record updatedOctober 20, 2025
Trial IDNCT05426928 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who are scheduled to undergo HIPEC surgery for abdominal cancer.

Probably not a fit

Patients who are pregnant, minors, or have diseases not suitable for HIPEC treatment will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to develop and validate a computational thermodynamic model to predict temperature changes in patients undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for abdominal cancers. By collecting real-world data from patients, the study will incorporate various factors such as patient demographics, anesthetic methods, and circulatory impacts to understand temperature variations during the procedure. The goal is to enhance the safety and effectiveness of HIPEC by providing clinicians with better predictive tools for managing body temperatures during treatment.

Why it matters

Potential benefit: If successful, this model could lead to improved safety and efficacy of HIPEC treatments for patients with peritoneal surface malignancies.

How similar studies have gone: While previous studies have explored abdominal hyperthermia, this specific approach to modeling temperature changes during HIPEC in humans is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults (at least 18 years or older)
* Scheduled to undergo HIPEC surgery for abdominal cancer at HFH-Main

Exclusion Criteria:

* Pregnant females
* Minors
* Disease not amenable for treatment with HIPEC after surgical examination.

Where it's running

  • Katherine Nowak
    Detroit, Michigan, United States
    Recruiting

Study contacts

  • Principal investigator: Carlos Guerra, MD — Staff Anesthesiologist
  • Study coordinator: Katherine Nowak, PhD
  • Email: knowak2@hfhs.org
  • Phone: 313-771-7128

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.