Investigating gut bacteria changes during stem cell transplant

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore how antibiotic use during stem cell transplant admissions affects the composition of intestinal microbiota over time. By collecting stool samples from patients at various stages of the transplant process, researchers will analyze the relationship between antibiotic regimens and changes in gut bacteria. The study focuses on understanding the potential impact of these changes on complications such as acute graft-versus-host disease (aGVHD) and relapse rates. This research could provide insights into optimizing antibiotic use to improve transplant outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18-80 years
* patients undergoing allogenic or autologous SCT for malignant hematological conditions or bone marrow failure

Where it's running

• Henry Ford Health System
  Detroit, Michigan, United States Recruiting

Study contacts

• Principal investigator: shatha farhan — Henry Ford
• Study coordinator: shatha farhan, MD
• Email: SFARHAN1@HFHS.ORG
• Phone: 313 916 5002

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.