NIH-funded research R01 grant

Understanding how sleep reactivity affects shift work disorder

Official title: Sleep reactivity as a novel mechanism in Shift Work Disorder

Funded at Henry Ford Health System · NIH-10910918 · Data updated 2026-11-12

This study is looking into why nightshift workers often feel really tired and have trouble sleeping, with the goal of finding better ways to help them feel better and stay healthy, rather than just giving them medication to manage the symptoms.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHenry Ford Health System
NIH-funded
Lab location1 site (Detroit, United States)
Project startSeptember 15, 2022
Project endAugust 31, 2027
Funding year2024
Award (this year)$672,607
NIH project number5R01HL160870-03
Project IDNIH-10910918 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who regularly work night shifts and experience symptoms of shift work disorder, such as excessive sleepiness or insomnia.

Less likely to help

Patients who do not work night shifts or do not experience symptoms related to shift work disorder may not benefit from this research.

What this research studies

This research investigates the mechanisms behind shift work disorder (SWD), which affects many nightshift workers who struggle with excessive sleepiness and insomnia. The study aims to identify the underlying biological factors contributing to SWD, moving beyond just managing symptoms with medications. By examining large clinical samples, the research seeks to develop targeted treatments that address the root causes of SWD, potentially improving the health and safety of those affected. The findings could lead to better management strategies for individuals who work non-traditional hours.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for shift work disorder, improving sleep quality and overall health for affected individuals.

How similar studies have gone: While there has been research on shift work disorder, this study aims to explore novel mechanisms, making it a potentially groundbreaking approach in this area.

Where this research is happening

  • Henry Ford Health System
    Detroit, United States
    Active

Researchers

  • Principal investigator: Cheng, Philip — Henry Ford Health System
  • Study coordinator: Cheng, Philip

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.