Understanding how sleep reactivity affects shift work disorder

Sleep reactivity as a novel mechanism in Shift Work Disorder

NIH-funded research Henry Ford Health System · NIH-10910918

This study is looking into why nightshift workers often feel really tired and have trouble sleeping, with the goal of finding better ways to help them feel better and stay healthy, rather than just giving them medication to manage the symptoms.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHenry Ford Health System NIH-funded
Lab location1 site (Detroit, United States)
Project IDNIH-10910918 on NIH RePORTER

What this research studies

This research investigates the mechanisms behind shift work disorder (SWD), which affects many nightshift workers who struggle with excessive sleepiness and insomnia. The study aims to identify the underlying biological factors contributing to SWD, moving beyond just managing symptoms with medications. By examining large clinical samples, the research seeks to develop targeted treatments that address the root causes of SWD, potentially improving the health and safety of those affected. The findings could lead to better management strategies for individuals who work non-traditional hours.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who regularly work night shifts and experience symptoms of shift work disorder, such as excessive sleepiness or insomnia.

Not a fit: Patients who do not work night shifts or do not experience symptoms related to shift work disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for shift work disorder, improving sleep quality and overall health for affected individuals.

How similar studies have performed: While there has been research on shift work disorder, this study aims to explore novel mechanisms, making it a potentially groundbreaking approach in this area.

Where this research is happening

Detroit, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Disease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.