Long-Term Effectiveness of Uterine-Sparing Fibroid Treatments for Black and White Women
Official title: Long Term Effectiveness of Uterine Sparing Fibroid Treatments
Funded at Henry Ford Health System · NIH-11372327 · Data updated 2026-11-12
This project follows real patients who had fibroid treatments to see how well symptoms and quality of life hold up over up to 10 years.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry Ford Health System NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $597,502 |
| NIH project number | 5R01HD109127-04 |
| Project ID | NIH-11372327 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women who previously received uterine-sparing fibroid treatments in COMPARE-UF or ULTRA registries and are willing to be followed for up to 10 years.
✕Less likely to help
Women who did not undergo uterine-sparing treatments or who are not part of the registries may not directly benefit from this study.
What this research studies
If you’ve had fibroid treatment like myomectomy, uterine artery embolization, or ablation, this study looks at how long benefits last and whether women still need further procedures as they approach menopause. Researchers will extend follow-up with hundreds of participants from two large registries to capture long-term outcomes, including symptom control, quality of life, pregnancy plans, and whether a hysterectomy becomes necessary. The study emphasizes real-world data across multiple sites to guide evidence-based choices for choosing among uterine-sparing options. It aims to identify which factors predict durable relief and which patients might need additional treatments later on.
Why it matters
Potential benefit: If successful, the findings could help doctors and patients choose uterine-sparing treatments with better long-term outcomes and clearer expectations.
How similar studies have gone: Previous follow-ups were limited to under 2 years, so this study adds extended data and could lead to stronger, evidence-based guidelines.
Where this research is happening
-
Henry Ford Health System
Detroit, United States Active
Researchers
- Principal investigator: Wegienka, Ganesa Rebecca — Henry Ford Health System
- Study coordinator: Wegienka, Ganesa Rebecca
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.