Condition

Vaccination clinical trials and research

• 17Clinical trials
• 233NIH research projects
• 1New in 30 days
• 12Countries

Newest Vaccination clinical trials

All recruiting trials (17)

• RSV vaccine safety and immune response in lung transplant patients vs. healthy adults

  This study tests how well the RSV vaccine works and how safe it is in people who have had a lung transplant compared with healthy adults.

  Recruiting Phase 4 Seoul National University Hospital · Seoul, Jongno-Gu · NCT07895394

• Sleep and Teens’ Immune Response to a Meningococcal Vaccine

  This study checks if 11- to 12-year-olds’ sleep habits affect how well their vaccine for meningococcal disease works.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07636525

• OptiMAx: testing SQ-LNS to boost vaccination in rural Chad and Niger

  This study tests whether giving small-batch SQ-LNS to young children helps increase routine immunizations in rural Chad and Niger.

  Recruiting at 2 sites Alliance for International Medical Action · Ngouri, Lac Region and 1 other locations · NCT07592260

• Using fingerprint-linked digital records and reminders to help children finish their malaria and routine vaccines

  This project will test whether a biometric-linked digital vaccination system plus voice-message reminders can help children in Ghana complete their malaria and routine vaccines.

  Recruiting University of Michigan · Oti Region · NCT07261280

• Which vaccine messages grab attention in rural New England

  This online test uses short social-media vaccine messages delivered by either experts or influencers to see which ones better catch attention and influence attitudes among adults living in rural New England.

  Recruiting University of Massachusetts, Worcester · Worcester, Massachusetts · NCT07236034

• Neutralizing power of blood and nasal antibodies

  This project will test how strong blood and nasal antibodies remain over time in adults getting COVID-19 or monkeypox vaccines or antibody treatments.

  Recruiting Centre Hospitalier Régional d'Orléans · Orléans · NCT07085611

• VITAL: Try time-restricted eating to improve vaccine responses in older adults

  This will test whether four weeks of time-restricted eating (an 8-hour daily eating window) helps people aged 60–85 mount stronger immune responses to seasonal influenza and COVID-19 vaccines.

  Recruiting Charite University, Berlin, Germany · Berlin · NCT07000708

• Morning versus evening flu vaccination for adults with chronic kidney failure

  This trial will test whether giving the seasonal flu shot in the morning produces a stronger immune response than giving it in the evening for adults with advanced chronic kidney disease, people on dialysis, and kidney transplant recipients.

  Recruiting Centre Hospitalier Universitaire de Nice · Nice, Alpes-Maritimes · NCT06907667

• Do personal story and informational videos encourage older adults to get vaccinated?

  This project will try informational videos, personal story videos, and a mix of both to see which best increases vaccination among U.S. adults aged 50 and older.

  Recruiting Johns Hopkins Bloomberg School of Public Health · New York, New York · NCT06890403

• Examining immune responses to vaccination in transgender and cisgender individuals

  This study tests how well the meningococcal serogroup B vaccine works in transgender and cisgender people by looking at their immune responses after getting the vaccine.

  Recruiting Phase 4 University Ghent · Ghent · NCT06832514

• Survey to assess eligibility for infectious disease clinical trials

  This study is trying to find out if people are eligible to join clinical trials for infectious diseases like HIV and vaccines by having them fill out a survey about their health and background.

  Recruiting Brooklyn Clinical Research · Brooklyn, New York · NCT06492187

• Evaluating COVID-19 vaccine effectiveness in lung cancer patients

  This study is testing whether getting a COVID-19 booster shot helps lung cancer patients on treatment avoid severe infections and stay healthier compared to those who don’t get the booster.

  Recruiting Peking Union Medical College Hospital · Beijing · NCT06168032

• Revaccination doses of hepatitis B vaccine for young adults

  This study tests the best way to give the hepatitis B vaccine to young adults in Taiwan who are at high risk and don't have enough protection against the virus.

  Recruiting National Taiwan University Hospital · Taipei, Taipei · NCT04970836

• Dengue vaccination strategy for children in the French Caribbean

  This study is trying to see how many children in Martinique and Guadeloupe have been exposed to dengue and whether parents are open to giving them the Dengvaxia® vaccine.

  Recruiting University Hospital Center of Martinique · Fort-de-France · NCT04839757

• Vaccination for liver transplant candidates

  This study tests if getting vaccinated can help people waiting for a liver transplant stay healthier and avoid serious infections.

  Recruiting Hospices Civils de Lyon · Lyon · NCT04446832

• Vaccination with Dendritic Cells for Patients with Resected Stage IV Rare Cancers

  This study is testing a new vaccine made from patients' own immune cells to see if it can help people who have had rare stage IV cancers feel better and stay healthy after surgery.

  Recruiting Phase 2 Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS · Meldola, FC · NCT04166006

• Collecting biological samples after vaccination

  This study is trying to see how different vaccines affect people's immune responses by collecting samples from those getting vaccinated as part of their regular care.

  Recruiting Assistance Publique - Hôpitaux de Paris · Créteil · NCT03875703

NIH-funded research (newest 40 of 233)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Protective dengue vaccines that steer T and B cell responses

  A vaccine study aims to guide the body’s T and B cells to fight all four dengue virus types safely and effectively.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11572336

• Respiratory pathogen–specific T cell signatures after vaccination, infection, and treatment

  A research effort to map how immune T cells respond to respiratory infections and vaccines, with potential to guide better vaccines and treatments for conditions like covid-19 and pertussis.

  NIH research La Jolla Institute for Immunology · La Jolla, United States · NIH-11537811

• Malaria vaccine and infection: how the body’s early and later immune responses relate to protection

  Researchers are studying how people’s immune systems respond to the malaria pre-erythrocytic stage, whether after vaccination or infection, to identify which responses are linked to protection.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-11535221

• Spatially responsive mass vaccination for urban rabies

  A new plan uses data and maps to place vaccination sites where they’re most needed in cities, aiming to boost rabies vaccination for both people and dogs.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11519711

• Spatially responsive mass vaccination for urban rabies

  A project tests smarter placement of vaccination sites to increase mass canine rabies vaccination in cities.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11519710

• Vaccine failure after Covid-19 vaccination in older adults

  This project follows vaccinated older adults to understand who among them still gets Covid-19 and what factors make those outcomes worse.

  NIH research Veterans Affairs Med Ctr San Francisco · San Francisco, United States · NIH-11515707

• Trusted school messengers boosting non-mandated vaccines for kids

  A school-based program aims to increase uptake of vaccines like influenza and HPV among children by using trusted school staff to share accurate vaccine information.

  NIH research University of Rochester · Rochester, United States · NIH-11503940

• ARISe Center for Rural Vaccination at UMass Chan Medical School

  A center at UMass Chan Medical School is being created to study and improve vaccination in rural areas across New England.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11503939

• Engaging schools to reduce kinds of vaccine exemptions

  A program with Georgia, Wisconsin, and Idaho schools to help families stay up to date on kindergarten vaccines by addressing real reasons for exemptions.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11503936

• How the immune system responds to dengue vaccines and infection

  This project compares immune reactions in people given different dengue vaccine formulations to find why one vaccine fully prevented DENV-2 infection while another did not.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11481645

• How the immune system responds to flu shots and flu infection

  This project looks at how adults' immune systems react after flu shots or when they catch the flu to find why some people get better protection than others.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11481644

• How different COVID-19 vaccines shape immune responses

  This project compares immune reactions after mRNA and adenoviral COVID-19 vaccines to learn how long protection lasts and why some people get breakthrough infections or side effects.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11481643

• How the RTS,S malaria vaccine protects young children in Africa

  This project uses blood tests and advanced lab analyses to find immune patterns that predict how well the RTS,S malaria vaccine protects young children in Malawi.

  NIH research Stanford University · Stanford, United States · NIH-11470646

• HIV vaccines in people with HIV on ART: how two vaccine designs shape T cell responses

  This study looks at how one versus two HIV vaccine components change T cell responses in people living with HIV who are on antiretroviral therapy.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11470445

• Bioinformatics platform to map HIV vaccine B-cell responses

  A national HIV vaccine research center is building a beginner-friendly data platform to study how B cells respond to HIV vaccines in people, with the goal of improving vaccines.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11468160

• RSV vaccination effects on heart and lung health in at-risk adults aged 50–59

  A Vanderbilt study will look at how RSV vaccines affect real-world heart and lung health in adults aged 50–59 who have higher risk due to other health conditions.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11427018

• BREATHE Well: Training early-childcare staff to boost vaccination discussions

  A training program for early childcare staff to help them talk with families about vaccines and respiratory health, with a focus on boosting uptake of vaccines like flu, COVID-19, and maternal RSV in Michigan centers.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11422089

• Jet vaccination to clear HPV16/18 infection in cervical precancer

  A Johns Hopkins team is testing a targeted vaccine approach to help people with persistent HPV16/18 infections clear the virus and reduce risk of cervical precancer.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11419153

• Oral rabies vaccination to boost dog vaccination in Tanzania

  This grant tests whether giving oral rabies vaccines to free-roaming dogs, alongside existing injections, can improve vaccination coverage and reduce rabies risk for dogs and people in Tanzania.

  NIH research Global Animal Health Tanzania · Arusha, Tanzania U Rep · NIH-11417954

• How prior dengue infections shape T cell responses after a new infection or vaccine

  This project looks at how a person’s existing dengue immunity affects their body's T cell response when exposed to a different dengue serotype or a live dengue vaccine, with a focus on kids and how this influences protection and safety.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11415564

• Protective immunity after dengue infections and vaccination

  Researchers are studying how our immune system remembers dengue and how vaccines influence that protection, aiming to spot clues that predict who remains protected or at risk after infection or vaccination.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11415532

• Malaria prevention in Malawi: smarter analysis of transmission and RTS,S vaccination for kids

  A large study in Malawi aims to understand how vaccination and mosquito control affect malaria risk in children, with a focus on how and where transmission happens.

  NIH research Kamuzu University of Health Sciences · Blantyre, Malawi · NIH-11415202

• Motivational interviewing to increase COVID-19 and flu vaccination

  This project teaches primary care providers conversational skills to help more adults, especially those in vulnerable communities, feel comfortable getting COVID-19 and flu shots.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11412464

• Improving HPV vaccination in rural primary care using proven strategies

  A rural health approach tests easy, evidence-based ways to boost HPV vaccination for teens to help prevent cancer.

  NIH research Roswell Park Cancer Institute Corp · Buffalo, United States · NIH-11412431

• Vaccination responses in lung transplant patients

  This grant studies how people who have received lung transplants respond to COVID-19 vaccines and why their antibody responses may be limited.

  NIH research Stanford University · Stanford, United States · NIH-11406132

• Adjuvants for Skin mRNA Vaccines to Make Flu Shots Better

  A study to test a new adjuvant delivered through the skin or nose to make flu mRNA vaccines work better and longer lasting.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11404893

• How our immune system keeps a memory of vaccines and infections over time

  A long-term study to understand how T cells remember SARS-CoV-2 vaccines and infections, and how this compares with common cold coronaviruses.

  NIH research La Jolla Institute for Immunology · La Jolla, United States · NIH-11398855

• Respiratory pathogen–specific T cell signals after infection and vaccination

  A study to map how immune T cells respond to flu, RSV, coronaviruses, TB, and pertussis after infection or vaccination, to help guide better vaccines and treatments.

  NIH research La Jolla Institute for Immunology · La Jolla, United States · NIH-11398846

• Multilevel Peer-to-Peer HPV Vaccination and Wellness Education in School Health Centers

  A school-based program helps medically underserved adolescents learn about HPV vaccination and wellness through peer-led outreach and collaboration with schools and health centers.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11397770

• Early-life metal exposure and child vaccine antibody responses

  This project looks at how metals exposure in early life may shape a child’s antibody response to vaccines years later.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11397544

• Text reminders to help girls finish the HPV vaccine series in Kampala

  This project sends SMS reminders to preteen and adolescent girls and their caregivers in Kampala, Uganda to help them complete all HPV vaccine doses.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11397404

• Personalized HIV Vaccine to Boost Your Own Protective Antibodies

  A personalized vaccine approach aims to strengthen a person’s own antibodies after early HIV treatment to try to achieve control of the virus without ongoing ART.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11395623

• How therapeutic HIV vaccination changes T-cell responses

  This project looks at whether therapeutic HIV vaccines can create new, better-working T cells in people living with HIV.

  NIH research University of California at Davis · Davis, United States · NIH-11391004

• Zika antibody immunity after infection and vaccination in kids

  Kids aged 0-11 could benefit from better vaccines and immunity tests for Zika as scientists study how antibodies from infection or vaccination protect against the virus.

  NIH research Emory University · Atlanta, United States · NIH-11390029

• How COVID-19 vaccines and gut microbes shape antibody responses

  This project compares antibody and B cell responses to two COVID-19 vaccines and looks at how gut microbes affect those responses in people who get vaccinated.

  NIH research Stanford University · Stanford, United States · NIH-11388612

• How T cells respond to COVID-19 and rabies vaccines

  This project looks at how mRNA and adjuvanted COVID-19 vaccines, and the effects of antibiotics given before rabies vaccination, change T cell responses in adults including people with allergies.

  NIH research Stanford University · Stanford, United States · NIH-11388607

• How COVID-19 vaccines trigger early immune responses

  This project looks at how different COVID-19 vaccine types and the gut microbiome shape early immune responses in adults, including people with serious allergies.

  NIH research Stanford University · Stanford, United States · NIH-11388605

• How COVID-19 vaccines and the microbiome shape immune responses

  This project looks at how different COVID-19 vaccines and the gut microbiome change immune responses in adults, including people with serious allergies.

  NIH research Stanford University · Stanford, United States · NIH-11388579

• Universal flu vaccine strategy to protect against diverse influenza strains

  A research team is testing new vaccine designs aimed at broad protection against many flu strains for people who want lasting immunity.

  NIH research Rockefeller University · New York, United States · NIH-11384802

• RSV vaccine in people with immune suppression: how antibodies form and work

  This grant studies how vaccines for RSV work in people with weakened immune systems and aims to improve how vaccines protect them.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11384417

Related topics

Quick answers

How many Vaccination clinical trials are recruiting right now?

17, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (4 trials), France (4 trials), Taiwan (1 trial), Germany (1 trial), Chad (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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