NIH-funded research R01 grant

Improving HPV vaccination in rural primary care using proven strategies

Official title: Implementation of evidence-based strategies to optimize HPV vaccination in rural primary care settings

Funded at Roswell Park Cancer Institute Corp · NIH-11412431 · Data updated 2026-11-12

A rural health approach tests easy, evidence-based ways to boost HPV vaccination for teens to help prevent cancer.

More Primary Care research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRoswell Park Cancer Institute Corp
NIH-funded
Lab location1 site (Buffalo, United States)
Project startAugust 21, 2022
Project endApril 30, 2027
Funding year2026
Award (this year)$527,764
NIH project number5R01MD016850-05
Project IDNIH-11412431 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents aged roughly 11–18 years seen in participating rural primary care practices.

Less likely to help

Adolescents outside the study’s geographic area or not within participating clinics may not experience direct benefits.

What this research studies

This project focuses on rural primary care clinics and uses a team-based, practice-facilitation approach to implement proven strategies for increasing HPV vaccination among adolescents. It will test a structured, implementation-focused plan (PC TEACH) designed to fit rural communities, culture, and health-system realities. The study uses a stepped-wedge cluster randomized design to evaluate how well these strategies raise HPV vaccination rates and reduce delays in vaccination across practices.

Why it matters

Potential benefit: If successful, this work could lead to higher HPV vaccination rates in rural areas, helping prevent HPV-related cancers for adolescents.

How similar studies have gone: Preliminary evidence from other settings suggests practice-facilitation and evidence-based prompts can improve vaccination uptake, with this study adapting those approaches for rural clinics.

Where this research is happening

  • Roswell Park Cancer Institute Corp
    Buffalo, United States
    Active

Researchers

  • Principal investigator: Rodriguez, Elisa Marie — Roswell Park Cancer Institute Corp
  • Study coordinator: Rodriguez, Elisa Marie

Related research

Other NIH-funded projects on the same topics.

  • Improving HPV vaccination rates in underserved primary care settings

    This study is all about finding better ways to help teens in underserved communities get their HPV vaccinations, so they can stay healthy, by using proven strategies that haven't been widely used yet.

    NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11178412

  • HEARTS hypertension and diabetes care in Guatemala

    This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11645315

  • Primary Care HEART-NET: boosting access to research in the Deep South

    A collaboration across three universities will build primary care research networks in Alabama, Arkansas, and Mississippi to improve access to care and help prevent and manage chronic diseases.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11618658

  • Primary Care Bridge: Building Research in Diverse Geographic Settings

    A national network hub in New Mexico will connect rural clinics and communities to faster, more usable primary care research so patients in underserved areas can benefit from new evidence.

    NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11618652

  • WREN: Expanding Research Capacity in Rural Primary Care Clinics

    A nationwide network in Wisconsin will strengthen rural primary care clinics to participate in real-world research and bring more clinical trials to communities.

    NIH research University of Wisconsin-Madison · Madison, United States · NIH-11618649

  • Primary care research network in Oklahoma to boost rural patient trials

    A nationwide NIH-supported effort to strengthen Oklahoma’s primary care research network so doctors can run big clinical trials and real‑world studies in rural communities.

    NIH research University of Oklahoma Hlth Sciences Ctr · Oklahoma City, United States · NIH-11618645

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.