Condition

Transplant clinical trials and research

• 15Clinical trials
• 369NIH research projects
• 6Countries

Newest Transplant clinical trials

All recruiting trials (15)

• Assessing diabetes risk in cirrhosis patients before and after liver transplant

  This study is trying to find out what factors might lead to diabetes in adults with liver cirrhosis before and after they get a liver transplant.

  Recruiting University of Chicago · Chicago, Illinois · NCT06950788

• XVIVO Heart Box non-ischemic preservation for transporting donor hearts.

  This program tests whether the XVIVO non-ischemic heart preservation system can safely preserve extended-criteria donor hearts for adults waiting for a heart transplant.

  Recruiting at 14 sites XVIVO Perfusion · La Jolla, California and 13 other locations · NCT06895070

• Non-Invasive Monitoring of Pediatric Kidney Transplant Recipients and Personalization of Immunosuppression

  This study tests whether non-invasive biomarkers can guide care in kids with kidney transplants to reduce biopsies and tailor immunosuppressive drug exposure.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT06761482

• Virtual home-based exercise program for kidney transplant candidates

  This study is testing a 12-week online exercise and education program for people waiting for a kidney transplant to see if it helps them get stronger before surgery.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT06089473

• Non-invasive methods to diagnose complications after liver transplantation

  This study is testing new, non-invasive ways to spot complications early in people who have had a liver transplant to help improve their recovery.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT05793203

• Assessing kidney function recovery after simultaneous liver and kidney transplants

  This study is testing how well kidney function improves in patients who get a liver and kidney transplant at the same time.

  Recruiting Indiana University · Indianapolis, Indiana · NCT05717842

• High intensity interval training for pediatric heart transplant recipients

  This study is testing a 12-week home workout program to see if it can help kids who have had a heart transplant get stronger and feel better.

  Recruiting University of Alberta · Edmonton, Alberta · NCT05451979

• Registry for adults with congenital heart disease and heart transplantation

  This study is collecting information about adults with congenital heart disease who may need a heart transplant to better understand their experiences and outcomes.

  Recruiting Universitätsklinikum Hamburg-Eppendorf · Hamburg, Free and Hanseatic City of Hamburg · NCT04848844

• How cardiopulmonary exercise affects AlloSure donor-derived cell-free DNA in heart transplant recipients

  This will test whether exercise changes donor-derived cell-free DNA measured by AlloSure in people who have had heart transplants.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT04656080

• Transplanting both a kidney and a bladder at the same time

  This study is testing if it's possible to safely transplant both a kidney and a bladder at the same time in patients who have kidney problems caused by bladder issues.

  Recruiting at 2 sites Early Phase 1 Mayo Clinic · Rochester, Minnesota and 1 other locations · NCT04626167

• Using hearts from donors with active hepatitis C (HCV NAT+) for transplantation

  This tests whether receiving a heart from a donor with active hepatitis C (HCV NAT+) is safe and leads to acceptable outcomes for people having a heart transplant.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT04493385

• Improving kidney function during donor anesthesia

  This study tests whether giving Mannitol, Dopamine, or extra fluids during anesthesia can help improve kidney function for patients receiving a kidney transplant from a living donor.

  Recruiting Cairo University · Cairo · NCT03778944

• Transplanting abdominal wall tissue to repair defects

  This study is testing if transplanting abdominal wall tissue can safely fix defects in the abdominal area for people who need it.

  Recruiting Duke University · Durham, North Carolina · NCT03310905

• Transplanting abdominal wall tissue to repair defects

  This study is testing if transplanting abdominal wall tissue can safely fix defects in the abdominal area for people who need it.

  Recruiting Duke University · Durham, North Carolina · NCT03310905

• Transplanting abdominal wall tissue to repair defects

  This study is testing if transplanting abdominal wall tissue can safely fix defects in the abdominal area for people who need it.

  Recruiting Duke University · Durham, North Carolina · NCT03310905

NIH-funded research (newest 40 of 369)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Targeting early oral GVHD to improve mouth health after stem cell transplant

  A study at UW–Madison will explore why some transplant patients develop painful oral GVHD and test ideas to prevent and lessen mouth-related problems.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11616478

• Innate and Adaptive Immunoregulation in Liver Transplant Ischemia/Reperfusion Injury

  A liver transplant-focused project investigates how the body’s early and later immune responses affect transplant failure or success after reperfusion.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11594128

• Exercise-based frailty program for people awaiting lung transplants

  A tailored exercise and lifestyle program is being tested to reduce frailty and improve outcomes for people waiting for a lung transplant.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11550096

• Diabetes and Donor Tissue in Corneal Transplants

  This grant studies whether corneas from donors with diabetes affect the success of Descemet membrane endothelial keratoplasty (DMEK) and what factors predict better or worse outcomes.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11531413

• Microbial clues to diagnose and predict infections in kidney transplant patients

  A patient-focused project will look for microbial biomarkers in stool, blood, and urine to help doctors predict and diagnose infections in people who have had a kidney transplant.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11471530

• Medicare Advantage and Transplant Access for Rural and Vulnerable Communities

  Aimed at understanding how Medicare Advantage affects early steps to kidney transplant for adults in rural or socioeconomically challenged groups.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11450384

• Maximizing transplant opportunities with deceased-donor initiated kidney paired donation chains

  Aimed at expanding kidney transplants by using deceased donors to kick-start chains that connect living donors with patients in need.

  NIH research New York University School of Medicine · New York, United States · NIH-11450243

• Immunological mechanisms behind treatment-resistant kidney transplant rejection

  This grant explores why certain kidney transplant rejections don’t respond to standard treatments and what immune cells in the graft are driving that resistance.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11449432

• Engineered human liver tissue to help with liver disease and drug-induced injury

  A scientist team is testing engineered human liver tissue that could temporarily support people with severe liver disease or liver injury when a full transplant isn’t possible.

  NIH research University of Washington · Seattle, United States · NIH-11447378

• Dyadic transplant self-care: how caregivers shape outcomes

  A study will look at how patients awaiting lung transplants and their caregivers work together to manage post-transplant care and what this means for health and recovery.

  NIH research Villanova University · Villanova, United States · NIH-11446288

• Dynamic metabolism shaping immune responses after heart transplant

  This project studies how gut bacteria and their metabolism influence immune reactions and long-term heart transplant success.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11446230

• Optimal donor choices for stem cell transplants using Bayesian learning in the cyclophosphamide era

  A research project will use patient data to help doctors pick the best donor for stem cell transplants in the era of cyclophosphamide-based GVHD prevention.

  NIH research Medical College of Wisconsin · Milwaukee, United States · NIH-11445103

• LIFT Clinic: Post-Transplant Alcohol Care Pilot

  A patient-centered plan to help people who had a liver transplant stay abstinent from alcohol, using structured monitoring and coordinated care.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11442475

• Complement-Bound Exosomes and Kidney Transplant Immunity

  This project studies how kidney transplant injury and rejection happen after surgery and whether blocking certain immune pathways during organ preservation could improve transplant outcomes.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11442411

• Blood vessel signals predicting heart problems after kidney transplant

  This project studies blood markers and tissue patterns after kidney transplants to identify which patients are at highest risk of cardiovascular problems.

  NIH research Yale University · New Haven, United States · NIH-11441506

• Understanding how BK virus links infection to kidney transplant rejection

  This project looks at how BK polyomavirus reactivation affects kidney transplant patients and aims to use pre-transplant T cell information to tailor immunosuppression and monitoring.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11436797

• Characterization of a LILRB3 SNP cluster and its link to kidney transplant outcomes

  A study in kidney transplant recipients looks at genetic factors that may be tied to higher risk of graft failure.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11434426

• Biomarker-guided reduction of immunosuppression after liver transplant

  A multicenter trial tests whether using blood biomarkers to guide tapering of immunosuppression in adults with liver transplants can keep people healthy while lowering drug exposure.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11433277

• Understanding why a lung transplant sometimes fails early and how to tailor treatment

  A study of people receiving lung transplants to find molecular differences that cause early graft failure and point to better, personalized therapies.

  NIH research Northwestern University · Chicago, United States · NIH-11429612

• Understanding how liver disease progresses in people waiting for a liver transplant

  A study will build a knowledge base that maps how liver disease worsens over time in patients on the transplant waitlist to improve care and planning.

  NIH research University of Florida · Gainesville, United States · NIH-11428230

• Stimulant that grows donor stem cells in the body to speed neutropenia recovery after chemotherapy and stem cell transplant

  A drug given during or right before stem cell transplant helps donor stem cells multiply quickly inside the patient to shorten neutropenia after treatment.

  NIH research Ship of Theseus, LLC · Eagleville, UNITED STATES · NIH-11424742

• Memory-like NK cell therapy for AML relapse after transplant

  A study exploring a novel immune therapy using donor memory-like NK cells to help people whose AML returned after a donor stem cell transplant.

  NIH research Washington University · Saint Louis, United States · NIH-11423680

• Optimizing a prehabilitation program for kidney transplant candidates on dialysis

  A program to improve physical function and readiness for kidney transplant in people on dialysis is being developed and tested to help candidates stay healthier while they wait.

  NIH research New York University School of Medicine · New York, United States · NIH-11421433

• New Patient‑Centered Transplant Center Report Cards

  A patient-focused project aims to make transplant center information easier to understand so people choosing a center can compare options and make informed decisions.

  NIH research University of Texas Med Br Galveston · Galveston, United States · NIH-11421134

• Remote home-based rehab to improve fitness before kidney transplant

  A home-based rehabilitation program is being tested to help adults awaiting kidney transplants become fitter and stronger while they wait.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11419006

• Targeting inflammation and alloimmunity in lung transplant recipients with clazakizumab

  A study to see if blocking IL-6 with clazakizumab can improve survival and reduce rejection in people who have received a lung transplant.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11416426

• Interventions to Promote Kidney Transplant Empowerment

  A targeted program to help adults with kidney disease navigate and complete the steps toward kidney transplant by addressing barriers and streamlining evaluation and waitlisting.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11415080

• Personalized immunosuppression for kidney transplant recipients using real-world data and AI

  A kidney transplant grant aims to tailor immunosuppressive therapy to individual patients using real-world health data and artificial intelligence.

  NIH research New York University School of Medicine · New York, United States · NIH-11413765

• Post-transplant care with biomarkers and support tools for alcohol-use after liver transplant

  A Johns Hopkins program tests biomarker-guided and behavioral approaches to help people who had a liver transplant for alcohol-related disease stay abstinent and healthy.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11413517

• Biomarkers to tailor liver transplant immunosuppression

  A multi-center study using blood biomarkers to guide how immunosuppressive drugs are given to liver transplant patients.

  NIH research Northwestern University · Chicago, United States · NIH-11412569

• Vaginal microbiota transplant to promote Lactobacillus-dominant cervicovaginal communities

  A clinical trial tests whether transferring vaginal microbiota from healthy donors can establish Lactobacillus-dominant vaginal communities to reduce risks linked with bacterial vaginosis.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11411247

• Pediatric Heart Pump to Let Kids Go Home While Waiting for Transplant

  A new ultra-low-power pediatric heart pump is being developed so children awaiting a heart transplant can go home or live with the device.

  NIH research Corvion, INC. · Webster, United States · NIH-11407580

• Vaccination responses in lung transplant patients

  This grant studies how people who have received lung transplants respond to COVID-19 vaccines and why their antibody responses may be limited.

  NIH research Stanford University · Stanford, United States · NIH-11406132

• Cardiovascular and Kidney Protection with SGLT2 Inhibitors after Kidney Transplant

  A study testing whether SGLT2 inhibitors can improve long-term heart and kidney health for adults who have had a kidney transplant.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11404810

• The Post-Lung Transplant Aging in Immune Cells in Donor Lungs

  This grant explores how aging donor lungs affect lung transplant outcomes by studying immune cells called alveolar macrophages.

  NIH research Duke University · Durham, United States · NIH-11403947

• Fecal transplant to help alcohol-related liver disease

  A clinical trial will test whether a standardized oral fecal microbiota transplant (FMT) capsule can help people with alcohol-related liver disease drink less and feel mentally better.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11402247

• Improve how patients and providers talk about live-donor kidney transplants

  A study will look at how conversations during kidney transplant evaluations influence whether people receive a live-donor transplant.

  NIH research Temple Univ of the Commonwealth · Philadelphia, United States · NIH-11401474

• Virtually Supervised Exercise for Kidney Transplant Candidates

  A home-based, online-guided exercise program helps people waiting for a kidney transplant stay stronger and fitter.

  NIH research Palo Alto Veterans Instit for Research · Palo Alto, United States · NIH-11401349

• Virtually supervised exercise program for people waiting for a kidney transplant

  This project offers a home-based, virtually supervised exercise program to help people on the kidney transplant waitlist keep and rebuild muscle and stay more mobile.

  NIH research Palo Alto Veterans Instit for Research · Palo Alto, United States · NIH-11400620

• Cellular and Molecular Studies of Bone Marrow Transplant and GVHD

  Researchers are studying why graft-versus-host disease happens after bone marrow transplant and how to predict and prevent it for people who need this cancer treatment.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11400426

Related topics

Quick answers

How many Transplant clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (9 trials), Canada (2 trials), Germany (1 trial), Italy (1 trial), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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