Improving kidney function during donor anesthesia
Renal Graft Functional Enhancement During Donor Anesthesia: A Comparative Study of 3 Modalities
NA · Cairo University · NCT03778944
This study tests whether giving Mannitol, Dopamine, or extra fluids during anesthesia can help improve kidney function for patients receiving a kidney transplant from a living donor.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Cairo University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT03778944 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of three different interventions—Mannitol infusion, Dopamine infusion, and adequate hydration—on enhancing the function and perfusion of transplanted kidneys during donor anesthesia. It aims to determine which approach best supports renal graft function in patients undergoing living-donor kidney transplantation. The study focuses on patients with end-stage renal disease and compares the outcomes of the different anesthetic regimens.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with end-stage renal disease who are scheduled for living-donor kidney transplantation.
Not a fit: Patients with severe cardiac or hepatic dysfunction or coagulopathy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved kidney function and outcomes for patients receiving transplants.
How similar studies have performed: While there have been studies focusing on renal graft function, the specific combination of interventions in this study is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * end-stage renal disease, for living-donor kidney transplantation Exclusion Criteria: * severe cardiac or hepatic dysfunction * coagulopathy
Where this trial is running
Cairo
- Kasr Al-Ainy Hospital, Cairo University — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: Nazmy E Seif, MD
- Email: drnazmyseif@yahoo.com
- Phone: 01227400808
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Renal Failure Chronic, Transplant, Failure,Kidney, Anesthesia, Mannitol, Dopamine, Perfusion, Renal graft donor