Improving kidney function during donor anesthesia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of three different interventions—Mannitol infusion, Dopamine infusion, and adequate hydration—on enhancing the function and perfusion of transplanted kidneys during donor anesthesia. It aims to determine which approach best supports renal graft function in patients undergoing living-donor kidney transplantation. The study focuses on patients with end-stage renal disease and compares the outcomes of the different anesthetic regimens.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* end-stage renal disease, for living-donor kidney transplantation

Exclusion Criteria:

* severe cardiac or hepatic dysfunction
* coagulopathy

Where it's running

• Kasr Al-Ainy Hospital, Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Nazmy E Seif, MD
• Email: drnazmyseif@yahoo.com
• Phone: 01227400808

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Transplanting abdominal wall tissue to repair defects

  This study is testing if transplanting abdominal wall tissue can safely fix defects in the abdominal area for people who need it.

  Recruiting Duke University · Durham, North Carolina · NCT03310905

• Non-Invasive Monitoring of Pediatric Kidney Transplant Recipients and Personalization of Immunosuppression

  This study tests whether non-invasive biomarkers can guide care in kids with kidney transplants to reduce biopsies and tailor immunosuppressive drug exposure.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT06761482

• Virtual home-based exercise program for kidney transplant candidates

  This study is testing a 12-week online exercise and education program for people waiting for a kidney transplant to see if it helps them get stronger before surgery.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT06089473

• Assessing diabetes risk in cirrhosis patients before and after liver transplant

  This study is trying to find out what factors might lead to diabetes in adults with liver cirrhosis before and after they get a liver transplant.

  Recruiting University of Chicago · Chicago, Illinois · NCT06950788

• XVIVO Heart Box non-ischemic preservation for transporting donor hearts.

  This program tests whether the XVIVO non-ischemic heart preservation system can safely preserve extended-criteria donor hearts for adults waiting for a heart transplant.

  Recruiting at 14 sites XVIVO Perfusion · La Jolla, California and 13 other locations · NCT06895070

• Examining the effects of furosemide on toxin levels in chronic kidney disease patients

  This study is testing whether the diuretic furosemide affects the levels of certain toxins in the blood and urine of people with chronic kidney disease.

  Recruiting UMC Utrecht · Utrecht, Utrecht · NCT06750575

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.