NIH-funded research NIH-funded research

LIFT Clinic: Post-Transplant Alcohol Care Pilot

Official title: Implementation and Pilot of the LIFT Model for Post-Transplant Alcohol Use Disorder Care

Funded at Massachusetts General Hospital · NIH-11442475 · Data updated 2026-11-12

A patient-centered plan to help people who had a liver transplant stay abstinent from alcohol, using structured monitoring and coordinated care.

More Alcohol Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startAugust 11, 2026
Project endJuly 31, 2029
Funding year2026
Award (this year)$720,240
NIH project number1R34AA033514-01
Project IDNIH-11442475 on NIH RePORTER

Who could benefit from this research

Could help

Adults who have had a liver transplant for alcoholic liver disease and are at risk for relapse.

Less likely to help

Patients not experiencing relapse risk or those not enrolled in post-transplant care programs may receive limited direct benefit.

What this research studies

If you’ve received a liver transplant due to alcohol-related disease, this program would use regular alcohol monitoring and proven treatments to support you in staying abstinent. The team works closely across liver specialists, addiction experts, and social support services to reduce relapse risk. The project will test how feasible and acceptable this care model is in different transplant settings and how it might be sustained in routine practice.

Why it matters

Potential benefit: If successful, it could reduce relapse, lower complications, and improve graft survival after transplant.

How similar studies have gone: Early data from LIFT suggest lower relapse rates and better engagement with treatment, but broader feasibilityacross centers is being tested.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Zhang, Wei — Massachusetts General Hospital
  • Study coordinator: Zhang, Wei

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.