Assessing kidney function recovery after simultaneous liver and kidney transplants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the recovery of kidney function in patients who receive a simultaneous liver-kidney transplant. It will involve recruiting patients with kidney dysfunction and an estimated GFR between 25 and 40 who are not on dialysis. Participants will undergo a Mag3 nuclear medicine scan before and after the transplant to assess kidney function recovery. The study seeks to develop criteria based on GFR measurements and other factors to predict the likelihood of recovery of native kidney function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. \> 18 years old
2. Listed for Liver Transplant for ESLD and Kidney Transplant (not on dialysis at time of transplant surgery)
3. Candidates with two native kidneys.
4. Willing to participate and sign informed consent form.

Exclusion Criteria:

1. Unstable patients (e.g. in the ICU or those who are on Continuous Renal Replacement Therapy (CRRT) who cannot complete the nuclear medicine scan or those with AKI on Hemodialysis
2. Prior history of any solid organ transplant.
3. Those who are currently pregnant or breast feeding.
4. Patients who have Autosomal Dominant polycystic kidney disease

Where it's running

• IU Health University Hospital
  Indianapolis, Indiana, United States Recruiting

Study contacts

• Study coordinator: Mary Balmes-Fenwick, B.S.
• Email: mbalmes@iu.edu
• Phone: 317-948-7772

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.