Post-transplant care with biomarkers and support tools for alcohol-use after liver transplant
Official title: Project 2-Optimization of Post-Transplant care via Biomarkers and Behavioral Interventions
Funded at Johns Hopkins University · NIH-11413517 · Data updated 2026-11-12
A Johns Hopkins program tests biomarker-guided and behavioral approaches to help people who had a liver transplant for alcohol-related disease stay abstinent and healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | February 1, 2019 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $359,527 |
| NIH project number | 5P50AA027054-08 |
| Project ID | NIH-11413517 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with alcohol-associated liver disease who have received a liver transplant and are navigating post-transplant care.
✕Less likely to help
Patients who do not have alcohol-use disorder or who are not in the post-transplant period may not benefit.
What this research studies
This project looks at how to integrate evidence-based AUD treatments into routine post-transplant care to reduce relapse and improve survival. It builds on past findings that early vs standard transplant timing can yield similar outcomes and explores how post-transplant support can be optimized with technology-assisted interventions. The work uses biomarkers and behavioral strategies to support patients in maintaining abstinence during the critical years after transplantation. By studying real-world post-transplant care and refining practice, it aims to make recovery more durable for ALD patients.
Why it matters
Potential benefit: If successful, patients could have better long-term survival and quality of life after liver transplant through improved abstinence support.
How similar studies have gone: Previous randomized trials showed promising results for technology-assisted AUD treatments integrated into post-transplant care; this project builds on that foundation.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Chen, Po-Hung (Victor) — Johns Hopkins University
- Study coordinator: Chen, Po-Hung (Victor)
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.