Condition

Sleep Disturbance clinical trials and research

• 45Clinical trials
• 18NIH research projects
• 1New in 30 days
• 13Countries

Newest Sleep Disturbance clinical trials

All recruiting trials (45)

• Improving Sleep for Older Adults in the Emergency Department

  This project tests whether wearing a Fitbit overnight can help understand and improve sleep for adults 70 and older in the emergency department who are likely to be admitted.

  Recruiting at 2 sites University Health Network, Toronto · Toronto, Ontario and 1 other locations · NCT07928141

• Virtual Reality-Based Hypnotherapy to Help Pain, Sleep, and Mood in Spinal Cord Injury

  Adults with spinal cord injury will try adding short VR-based hypnotherapy sessions to their standard physiotherapy to see if it reduces pain and improves sleep and mood.

  Recruiting Istanbul Physical Medicine Rehabilitation Training and Research Hospital · Istanbul, Istanbul · NCT07846410

• Telephone-Coached Sleep Bibliotherapy for Dementia Caregivers

  This study tests whether an 8-week, telephone-guided sleep self-help program helps informal caregivers of people with dementia sleep better.

  Recruiting The Hong Kong Polytechnic University · Hung Hom, Kowloon · NCT07826663

• Sleep detection in long-term care residents

  This study tests how well contactless sleep sensors track sleep patterns in older adults living in long-term care facilities.

  Recruiting Eastern Switzerland University of Applied Sciences · Sankt Gallen, St.Gallen · NCT07819409

• Gut Feelings: Testing Prebiotic A and B vs placebo for anxiety in adults

  This study tests whether two prebiotic products can reduce anxiety feelings in adults compared with a placebo.

  Recruiting Holobiome, Inc. · Del Mar, California · NCT07752823

• Sleep More, Stress Less with Neuralli Mood

  This 90-day, open-label study tests whether daily Neuralli Mood capsules can help adults feel less stressed, sleep better, and improve mood and burnout symptoms.

  Recruiting Efforia, Inc · New York, New York · NCT07717385

• Personalized acoustic therapy to improve sleep for adults with insomnia.

  This study will test whether nightly personalized sound-frequency therapy can improve sleep architecture and sleep quality in adults with insomnia.

  Recruiting National University of Malaysia · Cheras, Kuala Lumpur · NCT07503223

• Comparing virtual reality and in-person art therapy for anxiety, well-being, and sleep in people with colorectal cancer

  This test will see if virtual reality art therapy or in-person art sessions can reduce anxiety and improve psychological well-being and sleep for adults with colorectal cancer receiving outpatient chemotherapy.

  Recruiting Dokuz Eylul University · Izmir, Balçova · NCT07464626

• Integrated Data for Healthy Aging in Taiwan

  This project tests whether combining clinical data, genomics, and microbiome information can help identify early aging-related risks in adults 40 and older in Taiwan.

  Recruiting at 2 sites Chang Gung Memorial Hospital · Taipei and 1 other locations · NCT07414680

• Self-acupressure to improve social jet lag in female health sciences students

  This randomized trial tests whether daily self-acupressure can improve social jet lag and sleep quality in 18-25 year-old female health sciences students compared with a sham procedure.

  Recruiting Nigde Omer Halisdemir University · Niğde, Merkez · NCT07410936

• Lemborexant to help Sleep and Delirium in older ICU patients

  This study tests whether lemborexant, a sleep medication, helps improve sleep and reduce delirium in adults 65 and older in the ICU.

  Recruiting Phase 4 Mahidol University · Bangkok · NCT07407400

• Stasis supplement to reduce stimulant medication side effects

  We will test whether taking Stasis daytime and nighttime supplements for three months reduces sleep problems, irritability, anxiety, and brain fog in adults on stimulant medication for ADHD.

  Recruiting Outliers, Inc. · Las Vegas, Nevada · NCT07380412

• Exercise as Medicine — strength and dance to ease menopausal symptoms

  This project will test whether regular strength or dance-based exercise, done three times a week for eight weeks, can reduce menopausal symptoms and improve sleep in women aged 45–55.

  Recruiting Linnaeus University · Kalmar · NCT07351006

• Sleep and circadian interventions for college students at high risk of suicide

  Three sleep-focused approaches are being tested to see if they can help reduce suicidal thoughts and depression in high-risk college students receiving psychiatric care.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07346014

• VR-enhanced progressive muscle relaxation for chronic symptoms after burn injury

  This will try progressive muscle relaxation with and without virtual reality to see if it helps adult burn survivors reduce chronic pain, itch, anxiety, sleep problems, or fatigue.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07317271

• SPARK Healthy Sleep: a single-session app program to improve sleep for college students at risk for psychosis.

  This program tests whether a 30-minute smartphone session can improve sleep and reduce stigma in Indiana University college students who report psychotic-like experiences.

  Recruiting Indiana University · Indianapolis, Indiana · NCT07119268

• Exploring how sleep disturbances affect lung cancer treatment outcomes

  This study is trying to see how sleep problems affect the success of immune treatments in people with lung cancer.

  Recruiting Second Xiangya Hospital of Central South University · Changsha, Hunan · NCT06975384

• Sleep and bright-light program for teens with depression and sleep problems

  This project will try a sleep-and-bright-light program to improve sleep and mood in teens aged 12–18 with moderate-to-severe depression and clinically significant sleep problems who are at risk for suicidal thoughts.

  Recruiting at 2 sites University of Pittsburgh · Philadelphia, Pennsylvania and 1 other locations · NCT06963463

• Assessing sleep disturbances in Turkish patients with multiple sclerosis

  This study is testing a new Turkish sleep questionnaire to see how well it works for people with multiple sclerosis who have sleep problems.

  Recruiting Istanbul Medeniyet University · Bağcılar, Istanbul · NCT06875908

• Adaptive care for Chinese cancer survivors with insomnia

  This study is testing whether a web-based therapy for insomnia or an online exercise program can help Chinese cancer survivors sleep better, and if those who still have trouble can benefit from more intensive face-to-face support.

  Recruiting The University of Hong Kong · Hong Kong · NCT06813235

• Testing a sleep intervention for expectant and new mothers

  This study is testing a new sleep program for expectant and new mothers to see if it can help them get better sleep during and after pregnancy.

  Recruiting Rhode Island Hospital · Providence, Rhode Island · NCT06737055

• Treatment options for shoulder injuries affecting sleep quality

  This study is testing four different treatments for people with shoulder injuries to see which one helps improve their sleep quality and reduce pain.

  Recruiting Medical University of Lodz · Lodz, Łódź Voivodeship · NCT06631976

• PILOT TEST OF VITA CALM PRODUCTS FOR MOOD AND SLEEP

  A small, 12-week study will test if Vita Calm Mood Booster and Vita Calm Deep Sleep can improve mood and sleep compared with a placebo in adults with sleep and emotional disturbances.

  Recruiting The University of Hong Kong · Hong Kong, Hong Kong · NCT06579183

• Using a Smart Bassinet to Improve Maternal Sleep and Mental Health

  This study is testing if a Smart Bassinet can help new mothers and their babies sleep better, which might also improve the mothers' mental health after giving birth.

  Recruiting University of Colorado, Colorado Springs · Colorado Springs, Colorado · NCT06544941

• Investigating sleep and circadian rhythm in critically ill children

  This study is testing if giving critically ill children in the PICU more light during the day and limiting their food to daytime hours can help improve their sleep patterns.

  Recruiting State University of New York at Buffalo · Buffalo, New York · NCT06505447

• Improving sleep for children undergoing stem cell transplants

  This study is testing a program to help children getting stem cell transplants sleep better in the hospital by giving families tools to create a more restful environment.

  Recruiting at 2 sites Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT06468618

• Combining sleep promotion and cognitive training to improve brain function in older ICU survivors

  This study is testing if helping older adults who survived ICU treatment sleep better and do brain exercises can improve their thinking skills.

  Recruiting University of Washington · Seattle, Washington · NCT06411561

• Using Midazolam to Improve Postoperative Pain Relief for Colorectal Cancer Patients with Anxiety or Sleep Issues

  This study is testing if giving midazolam before surgery can help colorectal cancer patients with anxiety or sleep issues feel less pain and recover faster afterward.

  Recruiting Sixth Affiliated Hospital, Sun Yat-sen University · Guangzhou, Guangdong · NCT06407518

• Evaluating the best time for resistance exercise to improve insulin sensitivity and sleep

  This study is testing whether doing resistance exercises in the morning or evening helps people aged 50-74 with overweight or obesity improve their insulin sensitivity and sleep quality.

  Recruiting University of Utah · Salt Lake City, Utah · NCT06366399

• Improving sleep to prevent depression and anxiety in at-risk adolescents

  This study is testing if a short therapy for sleep problems can help prevent depression and anxiety in teens aged 12 to 18 who are at risk because of their family history.

  Recruiting University of Calgary · Calgary, Alberta · NCT06358495

• Program to promote better sleep in adolescents

  This study is testing a new sleep program for teens aged 12-18 who struggle with getting enough sleep and feeling down, to see if it helps them sleep better compared to a quick session on healthy sleep habits.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT06240325

• Using weighted blankets to improve sleep in children with ADHD

  This study is testing whether using weighted blankets can help children with ADHD, ages 5 to 12, sleep better.

  Recruiting University Hospital Bispebjerg and Frederiksberg · Frederiksberg · NCT06194162

• Preventing insomnia in adults using a stepped care model

  This study is testing a new online program designed to help adults prevent insomnia by providing different levels of support based on how severe their sleep problems are.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06156293

• A stepped care model to improve access to cognitive behavioral therapy for insomnia

  This study is testing a new way to make cognitive behavioral therapy for insomnia more accessible to people in Hong Kong to see if it helps them sleep better.

  Recruiting Chinese University of Hong Kong · Shatin, New Territories · NCT06109363

• Investigating how opioid use affects sleep and circadian rhythms

  This study is trying to see how opioid use affects sleep and body clock patterns in people with opioid use disorder to find better ways to help them recover.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06104280

• Understanding sleep's impact on auditory processing in children with autism

  This study is trying to see how sleep problems affect hearing skills in children with autism by comparing those who have Central Auditory Processing Disorder to those who don’t.

  Recruiting Loma Linda University · Loma Linda, California · NCT06059352

• Using weighted blankets to help veterans with chronic pain and sleep issues

  This study tests if using weighted blankets can help veterans with chronic pain and sleep problems feel better.

  Recruiting at 2 sites VA Office of Research and Development · San Diego, California and 1 other locations · NCT05963607

• Improving sleep quality for nursing home residents with dementia

  This study is testing a new sleep program in nursing homes to see if it can help residents with dementia sleep better and improve their overall health.

  Recruiting at 3 sites University of Alabama, Tuscaloosa · Lakewood, Colorado and 2 other locations · NCT05820919

• Mindfulness practices to improve sleep in college students

  This study tests if mindfulness practices can help first-year college students who have trouble sleeping feel better and improve their sleep quality.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT05576090

• Using art therapy to improve emotional well-being in military personnel with PTSD

  This study tests whether art therapy can help military personnel with PTSD feel better emotionally and improve their mental health.

  Recruiting at 2 sites Walter Reed National Military Medical Center · Bethesda, Maryland and 1 other locations · NCT05414708

• Improving sleep to reduce delirium in hospitalized patients

  This study is testing a new sleep program to see if improving sleep can help hospitalized patients avoid delirium.

  Recruiting University of Ostrava · Ostrava, Česká Republika · NCT05402280

• Comparing home sleep apnea testing to in-lab testing in children

  This study is testing whether home sleep apnea tests are just as good as in-lab tests for diagnosing sleep apnea in children.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05382754

• Improving sleep to enhance cognition in early Alzheimer's disease using trazodone

  This study is testing if the sleep medication trazodone can help improve sleep and memory in people with early Alzheimer's disease who have trouble sleeping.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT05282550

• Improving sleep and skin symptoms in children with eczema using Dupilumab

  This study is testing if the medication Dupilumab can help improve sleep and skin symptoms in children aged 6 to 17 with moderate to severe eczema.

  Recruiting Phase 4 Northwestern University · Chicago, Illinois · NCT05042258

• Sleep health of assisted-living residents

  This project tries to see if sleep quality is linked with physical activity, functional ability, and memory in older adults living in assisted-living facilities.

  Recruiting University of Calgary · Calgary, Alberta · NCT04400617

NIH-funded research (18)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• SleepCARE: a patient-friendly way to help caregivers of brain tumor patients sleep better

  A small grant is testing a telehealth sleep program designed to help caregivers of people with primary malignant brain tumors sleep better and feel less stressed.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11452272

• Sleep-Related Threat in Intimate Partner Violence

  This project looks at a new type of sleep disturbance seen in people affected by intimate partner violence and aims to understand how safety concerns at night shape sleep problems.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11351129

• Mindfulness for Sleep and Symptom Relief in Hematologic Cancer Patients During Hospital Stay

  A physician-led mindfulness program delivered via a mobile app during hospitalization aims to improve sleep and reduce fatigue, distress, and pain for patients with blood cancers receiving high-dose chemotherapy.

  NIH research Duke University · Durham, United States · NIH-11349727

• Calm app for better sleep in blood cancer patients

  A patient-friendly app-based program uses Calm to help people with hematologic cancers sleep better and feel less distressed.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11309639

• Investigating how sleep issues affect emotional problems in Alzheimer's patients

  This study is looking at how sleep problems affect feelings and behavior in people with mild cognitive impairment and mild Alzheimer's disease, and it wants to find out if helping you sleep better can improve your mood and reduce anxiety or agitation.

  NIH research Stanford University · Stanford, United States · NIH-11180635

• Mindfulness for Better Sleep and Comfort in Cancer Patients

  This project offers a mindfulness program to help patients with blood cancers sleep better and feel more comfortable during and after their hospital stays for chemotherapy.

  NIH research Duke University · Durham, United States · NIH-11135362

• Using suvorexant to improve sleep in veterans with PTSD

  This study is looking at how a medication called suvorexant can help veterans with PTSD get better sleep and feel less anxious, by targeting the brain's sleep and memory systems.

  NIH research Veterans Affairs Med Ctr San Francisco · San Francisco, United States · NIH-11121723

• How teens' attention to social media and poor sleep may lead to social anxiety

  This project looks at whether paying more attention to social media content and having poor sleep relate to growing social anxiety in 12–20-year-olds.

  NIH research Florida International University · Miami, United States · NIH-11120970

• Using the Calm app to help hematological cancer patients with sleep problems

  This study is looking at whether the Calm meditation app can help people with chronic blood cancers sleep better, offering an easy and at-home way to tackle sleep problems without medication.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11074535

• Investigating how sleep problems affect emotional regulation in Alzheimer's patients

  This study is looking at how sleep problems might affect feelings of anxiety and restlessness in people with mild cognitive impairment and mild Alzheimer's Disease, and it will help us see if improving sleep through therapy can make these feelings better.

  NIH research Stanford University · Stanford, United States · NIH-11062801

• Mindfulness techniques to help hematologic cancer patients manage sleep issues during and after hospital treatment

  This study is testing a friendly online program called Nite2Day+ to help patients with blood cancers who have trouble sleeping while in the hospital, teaching them relaxation techniques to improve their sleep and feel better overall.

  NIH research Duke University · Durham, United States · NIH-10982416

• How early life stress and sleep issues affect brain development and depression risk in teens

  This study is looking at how stress and sleep problems in childhood can affect the way the brain develops, especially in areas that help manage emotions and stress, to see if these factors might increase the risk of depression in teenagers.

  NIH research Stanford University · Stanford, United States · NIH-10936530

• Understanding how social media affects sleep and anxiety in teenagers

  This study is looking at how using social media might affect feelings of anxiety and sleep problems in teens aged 12 to 20, and it wants to understand how these things are connected over time.

  NIH research Florida International University · Miami, United States · NIH-10919852

• Investigating how stress and social networks affect cognitive aging and Alzheimer's risk

  This study is looking at how long-term stress and social connections affect memory and thinking as we age, especially for those at risk of Alzheimer's and similar conditions, to find ways to help improve brain health for everyone.

  NIH research Boston University Medical Campus · Boston, United States · NIH-10895443

• Investigating how sleep issues affect emotional regulation in Alzheimer's patients

  This study is looking at how sleep problems might affect feelings of anxiety and depression in people with mild cognitive impairment and mild Alzheimer's disease, and it will see if better sleep can help improve these feelings by offering therapy for insomnia to some participants.

  NIH research Stanford University · Stanford, United States · NIH-10889906

• Understanding how pain sensitivity and sleep issues affect treatment outcomes in knee osteoarthritis patients

  This study is looking at how increased pain sensitivity and sleep problems affect treatment options for people with knee osteoarthritis, so we can find the best ways to help you feel better and sleep well.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10888200

• Using suvorexant to improve sleep for people with opioid use disorder

  This study is looking at whether the sleep medication suvorexant can help people who are going through opioid withdrawal sleep better than the usual sleep aid, trazodone, so if you're in this situation, your sleep might improve with suvorexant!

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10454583

• How sleep problems and inflammation affect social behavior in adults with schizophrenia

  This study is looking at how sleep problems and inflammation affect social skills and behavior in adults with schizophrenia, hoping to find new ways to help improve their daily interactions and overall quality of life.

  NIH research University of Southern Mississippi · Hattiesburg, United States · NIH-10438972

Related topics

Quick answers

How many Sleep Disturbance clinical trials are recruiting right now?

45, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (23 trials), Hong Kong (4 trials), Turkey (Türkiye) (4 trials), China (3 trials), Canada (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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