Sleep More, Stress Less with Neuralli Mood

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This exploratory, decentralized, single-arm study enrolls adults experiencing stress or sleep disruption to take two Neuralli Mood capsules daily for 90 days. Participants serve as their own controls by completing validated questionnaires before starting and after 90 days to measure perceived stress, sleep quality, mood, anxiety, depressive symptoms, happiness, and burnout, with safety and adherence checks throughout. Neuralli Mood contains probiotic and postbiotic gut-brain strains (L. plantarum PS128 and heat-treated L. paracasei PS23) administered as 30 billion CFU and 20 billion non-viable cells per day. The study design is prospective and open-label, without a concurrent control group, and aims to generate preliminary, individualized before-and-after information while acknowledging potential placebo and self-selection effects.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older and able to provide informed consent.
* Generally healthy adult experiencing stress, occasional sleep disruption, low mood, anxiety symptoms, or work-related burnout.
* Willing and able to take two capsules of Neuralli Mood daily for 90 days.
* Willing and able to complete electronic baseline, follow-up, adherence, and safety assessments.
* Has reliable access to the internet and an email-enabled device.

Exclusion Criteria:

* Pregnant or nursing.
* Known allergy or hypersensitivity to Neuralli Mood, probiotics, or any product ingredient.
* Severe or unstable gastrointestinal disease, including a condition for which probiotic use may be inappropriate.
* Immunocompromised status or current immunosuppressive therapy.
* Severe or unstable mood disorder, acute psychiatric symptoms, or a current risk of harm to self or others.
* A clinically significant sleep disorder for which participation or changes in symptoms should be managed by a healthcare professional.
* Cognitive impairment or another condition that prevents informed consent or reliable completion of study procedures.
* History of a severe allergic reaction when the investigator determines probiotic use may present an unacceptable risk.
* Use of a medication or presence of a medical condition for which a healthcare professional advises against probiotic supplementation.
* Any other circumstance that, in the investigator's judgment, makes participation inappropriate or unsafe.

Where it's running

• Efforia - Decentralized United States Study
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Matthew Amsden — Efforia, Inc
• Study coordinator: Matthew Amsden
• Email: help@efforia.com
• Phone: +13232844626

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.