Mindfulness for Sleep and Symptom Relief in Hematologic Cancer Patients During Hospital Stay
Official title: Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment
Funded at Duke University · NIH-11349727 · Data updated 2026-11-12
A physician-led mindfulness program delivered via a mobile app during hospitalization aims to improve sleep and reduce fatigue, distress, and pain for patients with blood cancers receiving high-dose chemotherapy.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | July 9, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $173,574 |
| NIH project number | 5K08CA283026-03 |
| Project ID | NIH-11349727 on NIH RePORTER |
Who could benefit from this research
✓Could help
Hematologic cancer patients currently admitted for high-dose chemotherapy who report insomnia symptoms during hospitalization and are able to use a mobile app.
✕Less likely to help
Patients without insomnia symptoms or unable to use a mobile app may not benefit from this intervention.
What this research studies
This project expands an in-hospital mindfulness program to the inpatient setting for people with severe blood cancers undergoing intensive treatment. Participants will be randomized to receive the Nite2Day+ program or Usual Care, delivered through a self-paced mobile app available in the hospital. The intervention teaches mindfulness practices and behavioral strategies to improve sleep, fatigue, distress, and pain, with the goal of being feasible, acceptable, and beneficial during the inpatient stay and after discharge. Outcomes will focus on sleep quality, fatigue, distress, mindfulness, and engagement, to determine if the program can be adopted in routine care.
Why it matters
Potential benefit: If successful, patients could experience better sleep and reduced fatigue and distress during hospitalization for hematologic cancer treatment.
How similar studies have gone: Prior piloting showed feasible delivery and meaningful improvements in insomnia and related symptoms, supporting extension to inpatient use.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Fisher, Hannah M — Duke University
- Study coordinator: Fisher, Hannah M
Related research
Other NIH-funded projects on the same topics.
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Mindfulness for Better Sleep and Comfort in Cancer Patients
This project offers a mindfulness program to help patients with blood cancers sleep better and feel more comfortable during and after their hospital stays for chemotherapy.
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Mindfulness techniques to help hematologic cancer patients manage sleep issues during and after hospital treatment
This study is testing a friendly online program called Nite2Day+ to help patients with blood cancers who have trouble sleeping while in the hospital, teaching them relaxation techniques to improve their sleep and feel better overall.
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Mindfulness and Self-Hypnosis for Pain in Older Adults
This grant tests non-drug ways like mindfulness and self-hypnosis to help people over 60 manage chronic pain.
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Mindfulness-based Support for Pain and Sleep in Young People with Sickle Cell Disease
A digital mindfulness program is being tailored for adolescents and young adults with sickle cell disease to help with pain and sleep and is being tested for practicality and early effectiveness.
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Mindfulness training to lower cardiovascular risk for moms and babies during pregnancy
A mindfulness program is being tested during pregnancy to help prevent high blood pressure and heart problems for mothers and their babies.
-
Mindfulness-enhanced brain stimulation for depression
This project tests whether combining a breath-focused attention training with targeted brain stimulation helps people with treatment-resistant depression think more clearly and feel better.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.