Investigating how sleep issues affect emotional problems in Alzheimer's patients
Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia
This study is looking at how sleep problems affect feelings and behavior in people with mild cognitive impairment and mild Alzheimer's disease, and it wants to find out if helping you sleep better can improve your mood and reduce anxiety or agitation.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11180635 on NIH RePORTER |
What this research studies
This research focuses on understanding how sleep disturbances contribute to emotional and behavioral symptoms in patients with mild cognitive impairment and mild Alzheimer's disease. By examining the connections between sleep quality, brain function, and neuropsychiatric symptoms, the study aims to determine if improving sleep can lead to better emotional regulation. Participants will be involved in a randomized controlled trial where they will receive either Cognitive Behavioral Therapy for Insomnia or a control treatment. The goal is to see if changes in sleep can positively impact emotional health and reduce symptoms like anxiety and agitation.
Who could benefit from this research
Good fit: Ideal candidates are individuals with mild cognitive impairment or mild Alzheimer's disease who experience sleep disturbances and emotional distress.
Not a fit: Patients with severe Alzheimer's disease or those without sleep disturbances may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that alleviate emotional distress and improve quality of life for Alzheimer's patients.
How similar studies have performed: Previous research has shown promising results in using cognitive behavioral therapy to improve sleep and emotional regulation in various populations, suggesting potential success in this approach for Alzheimer's patients.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Goldstein-Piekarski, Andrea — Stanford University
- Study coordinator: Goldstein-Piekarski, Andrea
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.