Mindfulness for Better Sleep and Comfort in Cancer Patients

Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment

NIH-funded research Duke University · NIH-11135362

This project offers a mindfulness program to help patients with blood cancers sleep better and feel more comfortable during and after their hospital stays for chemotherapy.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11135362 on NIH RePORTER

What this research studies

Patients with life-threatening blood cancers often struggle with insomnia, fatigue, distress, and pain, especially during and after high-dose chemotherapy in the hospital. We are testing a program called Nite2Day+ that uses mindfulness meditations and behavioral strategies to improve sleep and related symptoms. This program will be delivered through a mobile app while patients are in the hospital, and it aims to help them accept the challenges of their inpatient treatment. We hope this approach will make a significant difference in how patients feel during a very difficult time.

Who could benefit from this research

Good fit: Ideal candidates are patients with hematologic cancer who are experiencing insomnia symptoms during hospitalization for high-dose chemotherapy.

Not a fit: Patients who do not have hematologic cancer or are not experiencing insomnia during inpatient chemotherapy may not receive direct benefit from this specific program.

Why it matters

Potential benefit: If successful, this program could provide a valuable tool for blood cancer patients to manage sleep problems, fatigue, distress, and pain, improving their overall well-being during and after treatment.

How similar studies have performed: A previous version of this program, Nite2Day, showed strong feasibility, acceptability, and significant improvements in insomnia and other symptoms for patients after hospital discharge.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.