Combining sleep promotion and cognitive training to improve brain function in older ICU survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to address cognitive impairment in older adults who have survived intensive care unit (ICU) treatment. It employs a 2 x 2 factorial design to randomly assign 100 English- or Spanish-speaking participants, aged 60 and older, to one of four intervention groups: a combination of sleep promotion and cognitive training, sleep only, cognitive training only, or an active control. The interventions focus on enhancing sleep quality through earplugs and eye masks at night, alongside daily cognitive training sessions to improve cognitive function. The study will also monitor circadian rhythms to optimize the timing of cognitive training for maximum effectiveness.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age greater than or equal to 60 years old
* Current hospitalization at University of Washington Medical Center or Harborview Medical Center
* Intensive care unit (ICU) length of stay greater than 24 hours
* Recovery from critical care status to acute care status, and/or discharge out of ICU
* Fluent in English or Spanish
* Functional independence on activities of daily living prior to hospitalization (Katz Index = 6)

Exclusion Criteria:

* Documented history or suspicion of Alzheimer's disease or dementia, or current prescription of anti-dementia medication
* Documented history of bipolar disorder or schizophrenia
* Documented acute stroke or traumatic brain injury
* Severe vision impairment
* Severe hearing impairment
* Severe paralysis or dominant arm paresis
* Transfer from skilled nursing care facility or inpatient rehabilitation facility

Where it's running

• University of Washington
  Seattle, Washington, United States Recruiting

Study contacts

• Principal investigator: Maya N Elias, PhD, MA, RN — University of Washington
• Study coordinator: Maya N Elias, PhD, MA, RN
• Email: mnelias@uw.edu
• Phone: 206-543-8564

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.