Stasis supplement to reduce stimulant medication side effects
A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications
We will test whether taking Stasis daytime and nighttime supplements for three months reduces sleep problems, irritability, anxiety, and brain fog in adults on stimulant medication for ADHD.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 55 Years |
| Sex | All |
| Sponsor | Outliers, Inc. Industry-sponsored |
| Locations | 1 site (Las Vegas, Nevada) |
| Trial ID | NCT07380412 on ClinicalTrials.gov |
What this trial studies
This is a hybrid, two-arm, triple-blind, randomized, placebo-controlled trial comparing Stasis daytime and nighttime supplements to matching placebo over three months in adults aged 18–55 who are on a stable stimulant dose for ADHD. Participants complete both remote and in-person components at the Citruslabs site in Las Vegas, with biomarker collection and symptom questionnaires at baseline and follow-up visits. Key outcomes include changes in oxidative stress markers, salivary or serum cortisol, and patient-reported stimulant side effects such as sleep disturbance, irritability, anxiety, and cognitive fog. The trial excludes people with uncontrolled medical or psychiatric conditions, recent smokers, heavy alcohol users, and those taking other psychiatric medications.
Who should consider this trial
Good fit: Adults 18–55 who are U.S. residents, currently prescribed a stable dose of stimulant medication for ADHD for at least three months, and experiencing sleep difficulty, irritability, anxiety, or brain fog are ideal candidates.
Not a fit: People with uncontrolled chronic illnesses, those taking other psychiatric medications, pregnant or breastfeeding individuals, recent smokers or heavy drinkers, night shift workers, or anyone allergic to the product ingredients are unlikely to qualify or benefit from this trial.
Why it matters
Potential benefit: If successful, the supplement could reduce common stimulant side effects and improve sleep, mood stability, and cognitive clarity for adults taking ADHD medications.
How similar studies have performed: Some antioxidant- and cortisol-targeting supplements have shown mixed benefits for mood, sleep, or cognitive symptoms, but this specific Stasis formulation has not been widely tested in rigorous randomized trials.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18-55 years * Currently prescribed stimulant medication for ADHD * Experiencing: sleep difficulty, irritability, anxiety, brain fog * Stable medication dose ≥3 months * Healthy with no uncontrolled chronic conditions * Stable on supplements ≥3 months if applicable * US resident * Willing to maintain current habits Exclusion Criteria: * Chronic conditions (e.g. cancer, mental illness) * Use of psychiatric medications besides stimulants * Pregnancy, breastfeeding, thyroid, liver, kidney conditions * Recent smokers or heavy alcohol use * Night shift workers * Participation in other clinical trials * Allergies to product ingredients
Where this trial is running
Las Vegas, Nevada
- Citruslabs — Las Vegas, Nevada, United States (Recruiting)
Study contacts
- Study coordinator: Patrick Renner, MSc
- Email: hello@citruslabs.com
- Phone: 4242450284
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.