Using suvorexant to improve sleep in veterans with PTSD

Who could benefit from this research

What this research studies

This research investigates the use of suvorexant, a medication that blocks orexin receptors, to alleviate sleep disturbances commonly experienced by veterans suffering from posttraumatic stress disorder (PTSD). The study aims to understand how this medication can improve sleep quality and reduce hyperarousal symptoms associated with PTSD. By focusing on the orexin neuropeptide system, which plays a role in both sleep regulation and emotional memory, the research seeks to provide a more effective treatment option compared to traditional sleep medications that often have undesirable side effects. Participants will be monitored for changes in sleep patterns and overall PTSD symptoms throughout the study.

Why it matters

Where this research is happening

• Veterans Affairs Med Ctr San Francisco
  San Francisco, United States Active

Researchers

• Principal investigator: Inslicht, Sabra — Veterans Affairs Med Ctr San Francisco
• Study coordinator: Inslicht, Sabra

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.