How sleep problems and inflammation affect social behavior in adults with schizophrenia

Sleep disturbance and inflammation as determinants of social cognition and behavior: An intensive longitudinal study of adults with schizophrenia-spectrum disorders

NIH-funded research University of Southern Mississippi · NIH-10438972

This study is looking at how sleep problems and inflammation affect social skills and behavior in adults with schizophrenia, hoping to find new ways to help improve their daily interactions and overall quality of life.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionUniversity of Southern Mississippi NIH-funded
Lab location1 site (Hattiesburg, United States)
Project IDNIH-10438972 on NIH RePORTER

What this research studies

This research investigates how sleep disturbances and inflammation impact social cognition and behavior in adults with schizophrenia-spectrum disorders. By examining these factors, the study aims to identify new treatment targets that could improve social functioning and overall quality of life for individuals affected by these disorders. Participants will be monitored over time to assess the relationships between their sleep patterns, inflammation levels, and social cognitive abilities. The findings could lead to more effective interventions for enhancing daily living skills and social interactions.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with schizophrenia-spectrum disorders and experience sleep disturbances.

Not a fit: Patients who do not have schizophrenia-spectrum disorders or who do not experience sleep disturbances may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments that enhance social functioning and quality of life for individuals with schizophrenia-spectrum disorders.

How similar studies have performed: While some studies have explored the links between sleep, inflammation, and cognitive function, this specific approach focusing on social cognition in schizophrenia-spectrum disorders is relatively novel.

Where this research is happening

Hattiesburg, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.