How sleep problems and inflammation affect social behavior in adults with schizophrenia
Official title: Sleep disturbance and inflammation as determinants of social cognition and behavior: An intensive longitudinal study of adults with schizophrenia-spectrum disorders
Funded at University of Southern Mississippi · NIH-10438972 · Data updated 2026-11-12
This study is looking at how sleep problems and inflammation affect social skills and behavior in adults with schizophrenia, hoping to find new ways to help improve their daily interactions and overall quality of life.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern Mississippi NIH-funded |
| Lab location | 1 site (Hattiesburg, United States) |
| Project start | June 15, 2022 |
| Project end | June 14, 2026 |
| Funding year | 2022 |
| Award (this year) | $443,811 |
| NIH project number | 1R15MH129814-01 |
| Project ID | NIH-10438972 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have been diagnosed with schizophrenia-spectrum disorders and experience sleep disturbances.
✕Less likely to help
Patients who do not have schizophrenia-spectrum disorders or who do not experience sleep disturbances may not benefit from this research.
What this research studies
This research investigates how sleep disturbances and inflammation impact social cognition and behavior in adults with schizophrenia-spectrum disorders. By examining these factors, the study aims to identify new treatment targets that could improve social functioning and overall quality of life for individuals affected by these disorders. Participants will be monitored over time to assess the relationships between their sleep patterns, inflammation levels, and social cognitive abilities. The findings could lead to more effective interventions for enhancing daily living skills and social interactions.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments that enhance social functioning and quality of life for individuals with schizophrenia-spectrum disorders.
How similar studies have gone: While some studies have explored the links between sleep, inflammation, and cognitive function, this specific approach focusing on social cognition in schizophrenia-spectrum disorders is relatively novel.
Where this research is happening
-
University of Southern Mississippi
Hattiesburg, United States Active
Researchers
- Principal investigator: Jordan, Sara Sytsma — University of Southern Mississippi
- Study coordinator: Jordan, Sara Sytsma
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.