Understanding how pain sensitivity and sleep issues affect treatment outcomes in knee osteoarthritis patients
Central Sensitization and Sleep Disturbance as Predictors of Treatment Outcomes in Patients with Knee Osteoarthritis
This study is looking at how increased pain sensitivity and sleep problems affect treatment options for people with knee osteoarthritis, so we can find the best ways to help you feel better and sleep well.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10888200 on NIH RePORTER |
What this research studies
This research investigates the relationship between central sensitization, which is heightened pain sensitivity, and sleep disturbances in patients with knee osteoarthritis (KOA). It aims to understand how these factors influence the effectiveness of various treatment options, including behavioral therapies and medications. By analyzing patient responses to different interventions, the study seeks to improve treatment selection and outcomes for individuals suffering from KOA. Patients may be assessed for their pain levels and sleep quality to tailor interventions that best suit their needs.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults suffering from knee osteoarthritis who experience chronic pain and sleep disturbances.
Not a fit: Patients with knee osteoarthritis who do not have issues with pain sensitivity or sleep disturbances may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for patients with knee osteoarthritis, improving their quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the role of central sensitization and sleep disturbances in chronic pain conditions, indicating that this approach may yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Campbell, Claudia Michelle — Johns Hopkins University
- Study coordinator: Campbell, Claudia Michelle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.