Investigating sleep and circadian rhythm in critically ill children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot trial focuses on critically ill children aged 3 to 6 years in a pediatric intensive care unit (PICU) to assess the feasibility of measuring their sleep and circadian rhythms using actigraphy and salivary melatonin levels. The study will implement two interventions: providing daytime light exposure and restricting nutrition to daytime hours. By evaluating these interventions, the research aims to determine if chronotherapeutic care can be effectively integrated into routine PICU management. The ultimate goal is to improve the understanding of sleep patterns in this vulnerable population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Child age 3 to 6 years old on the day of PICU admission
2. English-speaking parent at the bedside
3. Child expected to remain in the PICU over 24 to 48 hours

Exclusion Criteria:

1. Child is in end-of-life care
2. The child is receiving neuromuscular blockade for any reason
3. Caregiver or parent not at the bedside

Where it's running

• John R. Oishei Children's Hospital
  Buffalo, New York, United States Recruiting

Study contacts

• Study coordinator: Amanda B Hassinger, MD
• Email: albrooks@buffalo.edu
• Phone: 716-323-0158

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Combining sleep promotion and cognitive training to improve brain function in older ICU survivors

  This study is testing if helping older adults who survived ICU treatment sleep better and do brain exercises can improve their thinking skills.

  Recruiting University of Washington · Seattle, Washington · NCT06411561

• Lemborexant to help Sleep and Delirium in older ICU patients

  This study tests whether lemborexant, a sleep medication, helps improve sleep and reduce delirium in adults 65 and older in the ICU.

  Recruiting Phase 4 Mahidol University · Bangkok · NCT07407400

• Improving Sleep for Older Adults in the Emergency Department

  This project tests whether wearing a Fitbit overnight can help understand and improve sleep for adults 70 and older in the emergency department who are likely to be admitted.

  Recruiting at 2 sites University Health Network, Toronto · Toronto, Ontario and 1 other locations · NCT07928141

• Predicting Extubation Problems With Machine Learning

  This study tests whether computer models can predict extubation failure in adults on ventilators in the ICU.

  Recruiting Universitas Indonesia · Jakarta, DKI Jakarta and 1 other locations · NCT07918924

• Levetiracetam Dosing in Critically Ill on CRRT

  This study tests how levetiracetam behaves in the bodies of adults on continuous renal replacement therapy to help figure out the best dosing.

  Recruiting Chulalongkorn University · Pathum Wan, Bangkok · NCT07918833

• Respiratory Physiotherapy in Critically Ill Pneumonia Patients

  This study tests whether a structured breathing and chest therapy program can change inflammatory biomarkers in adults with pneumonia in the ICU compared to usual care.

  Recruiting Hospital H+ Queretaro · Querétaro · NCT07909616

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.