Condition

Pancreas Cancer clinical trials and research

• 84Clinical trials
• 20NIH research projects
• 24Countries

Newest Pancreas Cancer clinical trials

All recruiting trials (84)

• Liquid biopsy biomarkers to detect and monitor pancreatic cancer

  Researchers test blood-based microRNA signals to see if they can identify pancreatic cancer risk or early disease in people with familial or hereditary risk or mucinous cysts.

  Recruiting Università Vita-Salute San Raffaele · Milan, MI · NCT07700992

• INSPIRE: Putting patient-reported info into multidisciplinary tumor boards

  This study tests whether adding electronic patient-reported outcomes to tumor board discussions can help guide treatment decisions for women with breast, gynecologic, pancreatic cancers and related cancers.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama and 2 other locations · NCT07671937

• MRI scan for detecting pancreatic cancer in people at high risk

  This study tests a dedicated pancreas MRI (MRP) tool to see if it helps find pancreatic cancer earlier in people with a strong family or genetic risk.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT07612046

• Cutting down ultra-processed foods for people at high cancer risk

  This project tests whether using the Open Food Facts smartphone app alongside nutrition education helps adults at high risk of cancer eat fewer ultra-processed foods.

  Recruiting at 2 sites Gustave Roussy, Cancer Campus, Grand Paris · Avignon and 2 other locations · NCT07436312

• Carbon nanoparticle‑loaded iron for advanced solid tumors

  This test uses direct injections of a carbon nanoparticle‑loaded iron medicine (CNSI‑Fe) to see if it can shrink tumors in adults with advanced solid cancers who have no effective standard treatment options.

  Recruiting at 4 sites Phase 1/2 Sichuan Enray Pharmaceutical Sciences Company · Beijing, Beijing Municipality and 8 other locations · NCT07433283

• Axelopran for adults with advanced breast, lung, pancreas, or prostate cancer who take opioids

  This trial will test whether taking axelopran can slow tumor progression, help bowel problems, and reduce inflammation in adults with advanced breast, lung, pancreas, or prostate cancer who are using opioid pain medicines.

  Recruiting at 2 sites Phase 2 HealthPartners Institute · Saint Louis Park, Minnesota and 1 other locations · NCT07354919

• Tissue-glue injection into the pancreas during pancreaticoduodenectomy

  This trial will test whether injecting a tissue glue called N-butyl-2-cyanoacrylate into the pancreatic remnant during pancreaticoduodenectomy reduces postoperative pancreatic fistulas in patients with a soft pancreas and a small main duct.

  Recruiting Phase 2 Minia University · Minya, Minya Governorate · NCT07230509

• CEA-targeted CAR-T for advanced CEA-positive solid tumors

  This trial will try CEA-targeted CAR-T cell infusions in adults with advanced CEA-positive cancers (such as colorectal, gastric, esophageal, lung, or pancreatic cancer) to see if the treatment is safe and helps control the disease.

  Recruiting Phase 1 Chongqing Precision Biotech Co., Ltd · Hefei, Anhui · NCT07179692

• Saleh's technique: injecting Histoacryl glue into the pancreas during pancreaticojejunostomy

  This procedure will try injecting a tissue glue (Histoacryl) into the pancreas during pancreaticoduodenectomy to see if it reduces pancreatic leaks in people with a soft pancreas and a small pancreatic duct.

  Recruiting Phase 1 Minia University · Minya, Minya Governorate · NCT07132541

• Combining SBRT with defactinib and avutometinib for advanced pancreatic cancer

  This Phase 2 trial tests whether adding the targeted drugs defactinib and avutometinib to adaptive SBRT helps people with locally advanced or borderline resectable pancreatic cancer stay progression-free longer than SBRT alone.

  Recruiting Phase 2 Washington University School of Medicine · St Louis, Missouri · NCT07126158

• Neoadjuvant chemotherapy versus immediate surgery for resectable pancreatic head and periampullary cancer

  This trial tests if giving chemotherapy before surgery helps people with resectable pancreatic head or periampullary cancer live longer than having immediate surgery followed by chemotherapy.

  Recruiting Phase 3 Minia University · Minya, Minya Governorate · NCT07081360

• Using ctDNA methylation to guide prognosis and monitoring in pancreatic cancer

  This project tests whether a blood test that measures ctDNA methylation can help detect and monitor pancreatic cancer in adults who are undergoing surgery or biopsy.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07045571

• Immune map of pancreatic cancer evolution

  This project will collect blood, tissue, imaging, and clinical data from people with pancreatic cancer, benign pancreatic lesions, and healthy volunteers to try to build an AI-based immune map that can detect and track pancreatic cancer.

  Recruiting First Affiliated Hospital of Zhejiang University · Hangzhou, Zhejiang · NCT07034339

• Predicting pancreatic fistula after pancreaticoduodenectomy

  This project will try to find which before-, during-, and after-surgery factors predict clinically significant pancreatic fistula in adults having pancreaticoduodenectomy for pancreatic or periampullary tumors.

  Recruiting Minia University · Minya · NCT07022015

• Early‑phase KESONOTIDE™ treatment for solid tumors

  This trial tests an oral drug called KESONOTIDE™ (a vimentin inhibitor) to see if it is safe and tolerable in adults with advanced or metastatic solid tumors like prostate, breast, lung, ovarian cancer, or glioblastoma.

  Recruiting at 3 sites Phase 1/2 Filamon LTD · Kogarah, New South Wales and 2 other locations · NCT06926075

• Testing LXP1788 Injection for Advanced Solid Tumors

  This study is testing a new injection called LXP1788 to see if it can safely help people with advanced solid tumors that haven't responded to other treatments.

  Recruiting at 2 sites Phase 1 LaunXP Biomedical Co., Ltd. · Taichung and 1 other locations · NCT06883539

• Evaluating pancreatic fistula rates after surgery using a specific stapler

  This study is testing if using a specific stapler during pancreas surgery can lower the chances of complications like pancreatic fistulas in patients.

  Recruiting University Hospital Heidelberg · Heidelberg, Baden-Wurttemberg · NCT06764134

• Comparing two methods for preventing pancreatic fistula after surgery

  This study is testing if using a special glue during pancreatic surgery can help prevent serious leaks in the pancreas compared to the usual method for people having surgery for cancer.

  Recruiting Phase 2 Minia University · Minya · NCT06756074

• Comparing standard and prolonged chemotherapy before surgery for pancreatic cancer

  This study is testing whether giving longer chemotherapy before surgery can help people with tough-to-treat pancreatic cancer live longer and have better outcomes.

  Recruiting Phase 3 Sahlgrenska University Hospital · Gothenburg, VGR · NCT06714604

• Measuring convertase levels in pancreatic adenocarcinoma tumors and blood

  This will test whether measuring convertase levels in tumor and blood samples can help predict disease progression in adults with pancreatic adenocarcinoma.

  Recruiting Institut Bergonié · Bordeaux · NCT06705335

• Improving outcomes for pancreatic cancer patients with limited metastases

  This study is testing if a combination of different treatments can help people with pancreatic cancer that has spread a little, to see if it improves their survival and quality of life compared to just one type of treatment.

  Recruiting at 4 sites Phase 3 M.D. Anderson Cancer Center · Camden, New Jersey and 3 other locations · NCT06593431

• Investigating QXL138AM for patients with advanced solid tumors and multiple myeloma

  This study is testing a new drug called QXL138AM to see if it can safely help people with advanced solid tumors and multiple myeloma.

  Recruiting at 11 sites Phase 1 Nammi Therapeutics Inc · Los Angeles, California and 10 other locations · NCT06582017

• Using Riluzole to Help Breast Cancer Survivors with Cognitive Issues

  This study is testing if the medication riluzole can help breast cancer survivors who are having trouble with thinking and memory feel better.

  Recruiting Phase 2 University of California, Irvine · Orange, California · NCT06580002

• Combining Bortezomib with PD-1 antibody and chemotherapy for advanced pancreatic cancer

  This study is testing a new combination of treatments, including Bortezomib, a PD-1 antibody, and chemotherapy, to see if it can help people with advanced pancreatic cancer.

  Recruiting Phase 1/2 Zhejiang University · Hangzhou, Zhejiang · NCT06572813

• Using Lipidica software to screen for pancreatic cancer in high-risk patients

  This study is testing a new software called Lipidica to see if it can help find pancreatic cancer earlier in people who are at high risk because of their genetics or family history.

  Recruiting at 15 sites Lipidica, a.s. · Prague, Czechia and 15 other locations · NCT06549725

• Oral treatment with MOMA-313 for advanced solid tumors

  This study is testing a new oral treatment called MOMA-313 for people with advanced solid tumors that can't be cured, to see how safe it is and how well it works, especially for those with certain genetic changes.

  Recruiting at 14 sites Phase 1 MOMA Therapeutics · Goodyear, Arizona and 17 other locations · NCT06545942

• Milaberon for treating advanced solid tumors

  This study is testing if a higher dose of mirabegron can help people with advanced solid tumors feel better while keeping an eye on any side effects.

  Recruiting Phase 2 Zhejiang Provincial People's Hospital · Hangzhou, Zhejiang · NCT06534762

• Treatment for advanced pancreatic cancer using engineered immune cells

  This study is testing a new treatment that uses specially modified immune cells to see if it can help people with advanced pancreatic cancer feel better and fight their disease.

  Recruiting Phase 1/2 University of Virginia · Charlottesville, Virginia · NCT06479239

• Surgery for pancreatic cancer with liver metastases after chemotherapy

  This study is testing whether surgery after chemotherapy can help people with pancreatic cancer that has spread to the liver live longer and have better outcomes.

  Recruiting Laval University · Québec, Quebec · NCT06349278

• Using tislelizumab to treat cancer patients with detectable tumor DNA after surgery

  This study is testing if the immunotherapy drug tislelizumab can help cancer patients who have had surgery and still have traces of tumor DNA in their blood to avoid a relapse.

  Recruiting Phase 3 Gustave Roussy, Cancer Campus, Grand Paris · Villejuif, Val De Marne · NCT06332274

• Using the HistoSonics Edison System to treat pancreatic cancer

  This study is testing a new treatment using the HistoSonics Edison System to see if it can safely destroy tumors in patients with advanced pancreatic cancer that can't be removed by surgery.

  Recruiting HistoSonics, Inc. · Barcelona · NCT06282809

• Evaluating eccDNAs as biomarkers for diagnosing biliary stricture

  This study is testing if a new type of DNA found in the blood can help doctors better diagnose patients with unclear bile duct blockages, especially to catch cancer earlier.

  Recruiting at 2 sites Peking University Third Hospital · Beijing, Beijing Municipality and 1 other locations · NCT06277531

• Improving care for Black patients with gastrointestinal cancer

  This study is trying to improve cancer care for Black patients with gastrointestinal cancers by ensuring they get the right tests and treatments while helping us understand the challenges they face.

  Recruiting Case Comprehensive Cancer Center · Cleveland, Ohio · NCT06263088

• Mobile app to increase Black participation in pancreatic cancer clinical trials

  This study is testing a new mobile app designed to help Black individuals with pancreatic cancer get more involved in clinical trials and improve their healthcare experience.

  Recruiting at 2 sites UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina and 1 other locations · NCT06252545

• Testing MGC026 in patients with advanced solid tumors

  This study is testing a new treatment called MGC026 to see if it can help adults with advanced solid tumors that can't be removed or have spread to other parts of the body.

  Recruiting at 12 sites Phase 1 MacroGenics · Los Angeles, California and 11 other locations · NCT06242470

• Personalized therapy for high-risk pancreatic cancer patients after surgery

  This study is testing if personalized treatment plans based on the unique characteristics of pancreatic cancer can help high-risk patients feel better and reduce the chance of their cancer coming back after surgery.

  Recruiting Medical College of Wisconsin · Milwaukee, Wisconsin · NCT06228599

• Using blood tests to manage gastrointestinal tumors

  This study is testing if blood tests that look for tumor DNA can help doctors better manage patients with gastrointestinal tumors like pancreatic, colon, and biliary tract cancers.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome, Lazio · NCT06202131

• CAR-γδT cell therapy targeting GPC3 and Mesothelin for cancer treatment

  This study is testing a new cancer treatment that uses modified immune cells to target specific proteins in patients with advanced solid tumors.

  Recruiting Phase 1 Second Affiliated Hospital of Guangzhou Medical University · Guangzhou, Guangdong · NCT06196294

• Using CAR-T cells to target B7-H3 in pancreatic cancer

  This study is testing a new treatment using specially modified immune cells to see if they can safely help people with pancreatic cancer that has come back after other treatments.

  Recruiting Phase 1 UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT06158139

• Using advanced imaging to detect and monitor pancreatic cancer

  This study is testing a new way to use advanced MRI images to better spot and track pancreatic cancer in patients, helping doctors catch it earlier and manage treatment more effectively.

  Recruiting Institut du Cancer de Montpellier - Val d'Aurelle · Montpellier · NCT06144762

• Treatment using CEA-targeted CAR-T cells for advanced solid tumors

  This study is testing a new type of immune therapy using CAR-T cells to see if it can help people with advanced solid tumors that have a specific marker called CEA.

  Recruiting Phase 1 Chongqing Precision Biotech Co., Ltd · Wuhu, Anhui · NCT06126406

• Investigating lymph node metastasis in pancreatic cancer surgery

  This study is testing whether removing certain lymph nodes during pancreatic cancer surgery can help doctors understand how the cancer spreads and improve treatment for patients.

  Recruiting at 2 sites Uppsala University Hospital · Odense and 5 other locations · NCT06065891

• Evaluating a new CAR T-cell therapy for solid tumors expressing MSLN

  This study is testing a new CAR T-cell therapy to see if it can safely treat adults with solid tumors like colorectal and lung cancer that express a specific protein.

  Recruiting at 12 sites Phase 1/2 A2 Biotherapeutics Inc. · Gilbert, Arizona and 11 other locations · NCT06051695

• Sintilimab combined with chemotherapy and radiotherapy for inoperable pancreatic cancer

  This study is testing if combining the immunotherapy drug Sintilimab with chemotherapy and radiotherapy can help people with inoperable pancreatic cancer live longer and feel better.

  Recruiting Phase 2 Shandong Cancer Hospital and Institute · Jinan, Shandong · NCT06050317

• Personalized T cell therapy targeting KRAS G12V in metastatic solid tumors

  This trial tests whether giving a patient's own modified CD8+ and CD4+ T cells engineered to recognize the KRAS G12V mutation can help people with metastatic solid tumors that carry that mutation.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06043713

• Targeting CEA with CAR-T cells for advanced solid tumors

  This study is testing a new type of CAR-T cell treatment for people with advanced solid tumors to see if it's safe and how well it works.

  Recruiting at 2 sites Phase 1 Chongqing Precision Biotech Co., Ltd · Hangzhou, Zhejiang and 1 other locations · NCT06043466

• Assessing the effects of radiotherapy on tumors in cervical and pancreatic cancer

  This study is testing how radiotherapy affects tumors in patients with locally advanced cervical and pancreatic cancer by collecting samples and using special imaging before, during, and after treatment.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT05975593

• Improving preoperative care for pancreatic surgery patients

  This study is testing a new health program to see if it helps patients get stronger and recover faster after pancreatic surgery.

  Recruiting at 13 sites Maastricht University Medical Center · 's-Hertogenbosch and 12 other locations · NCT05851534

• Acupuncture for treating nerve pain caused by chemotherapy in cancer patients

  This study is testing if acupuncture can help cancer patients with nerve pain caused by chemotherapy feel better after stopping their treatment.

  Recruiting at 9 sites GERCOR - Multidisciplinary Oncology Cooperative Group · Amiens and 14 other locations · NCT05850130

• Comparing Gemcitabine and Reduced-dose Combination Chemotherapy for Non-resectable Pancreatic Cancer

  This study is testing whether full-dose Gemcitabine or a lower-dose combination of Gemcitabine and Nab-Paclitaxel works better and is safer for older or frail patients with pancreatic cancer that can't be surgically removed.

  Recruiting Phase 2 Aalborg University Hospital · Aalborg · NCT05841420

• CAR-T cell therapy targeting mesothelin for cancer treatment

  This study is testing a new CAR-T cell therapy that targets a specific protein in advanced cancers, like pancreatic cancer, to see if it can help patients feel better and fight their disease.

  Recruiting Phase 1 Second Affiliated Hospital of Guangzhou Medical University · Guangzhou, Guangdong · NCT05779917

• Improving recovery after surgery with intravenous iron treatment

  This study tests if giving intravenous iron to patients who lose a lot of blood during major surgeries can help them recover better and need fewer blood transfusions.

  Recruiting Phase 3 Uppsala University Hospital · Uppsala, Sverige · NCT05744219

• Collecting blood samples to study biomarkers in pancreatic cancer

  This study is collecting blood samples from patients with pancreatic cancer to see if certain markers in the blood can help improve diagnosis and treatment options.

  Recruiting Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT05743049

• Combining radiation and tumor treating fields for advanced pancreatic cancer

  This study is testing if combining radiation therapy with a special device that delivers electric fields can help slow down tumor growth in people with advanced pancreatic cancer.

  Recruiting Baptist Health South Florida · Miami, Florida · NCT05679674

• Early detection of pancreatic cancer using a blood test

  This study is testing a new blood test to see if it can help find pancreatic cancer earlier in people who are at high risk or show signs of the disease.

  Recruiting Biological Dynamics · San Diego, California · NCT05625529

• Evaluating the ERAS program's impact on recovery after pancreatic surgery

  This study is testing if following a special recovery program can help people recover better after pancreatic surgery.

  Recruiting University of Thessaly · Larissa · NCT05518643

• Evaluating blood clotting parameters in cancer patients undergoing surgery

  This study is testing how blood clotting measurements in cancer patients before and after surgery can help predict complications and outcomes for those with different types of adenocarcinoma.

  Recruiting at 2 sites University of Colorado, Denver · Aurora, Colorado and 1 other locations · NCT05517811

• Comparing physical activity measurements in cancer patients

  This study tests whether questionnaires or motion trackers give a better picture of how active cancer patients are during their treatment.

  Recruiting University Medicine Greifswald · Greifswald · NCT05501379

• A network for collaborative cancer research in Ontario

  This study is testing a new way to improve cancer treatment by using genetics and technology to help personalize care for people with different types of cancer.

  Recruiting at 2 sites University Health Network, Toronto · Kingston, Ontario and 2 other locations · NCT05403177

• Assessing survival and quality of life in patients with advanced pancreatic cancer

  This study looks at how long people with advanced pancreatic cancer live and how their quality of life is affected while being treated at different hospitals in the Nordic region.

  Recruiting Umeå University · Umeå · NCT05356039

• Comparing preoperative and postoperative blood clot prevention in pancreatic surgery

  This study is testing whether giving blood clot prevention medication before or after pancreatic surgery works better to keep patients safe from clots.

  Recruiting at 5 sites Phase 4 Helsinki University Central Hospital · Toronto and 4 other locations · NCT05245877

• Using Bethanechol with Chemotherapy for Pancreatic Cancer Treatment

  This study is testing if adding bethanechol to chemotherapy can help people with pancreatic cancer have better surgery outcomes and if it's safe to use.

  Recruiting Phase 2 Columbia University · New York, New York · NCT05241249

• Combining surufatinib and camrelizumab with chemotherapy for advanced pancreatic cancer

  This study is testing a new combination of treatments for people with advanced pancreatic cancer to see if it works better than the standard options.

  Recruiting Phase 1/2 Chinese PLA General Hospital · Beijing · NCT05218889

• High dose short course radiotherapy for locally advanced pancreatic cancer

  This study is testing a new type of high-dose radiation therapy for people with locally advanced pancreatic cancer to see how well it works when combined with standard treatments.

  Recruiting EBG MedAustron GmbH · Wiener Neustadt, Lower Austria · NCT05191940

• Combination therapy using checkpoint inhibitors for advanced solid tumors

  This study is testing a new combination treatment using special antibodies for people with advanced solid tumors like lung and liver cancer to see if it can be safer and more effective than current options.

  Recruiting Phase 1/2 Second Affiliated Hospital of Guangzhou Medical University · Guangzhou, Guangdong · NCT05187338

• Analyzing factors affecting pancreatic tumors and cysts

  This study looks at how different factors affect pancreatic tumors and cysts to help improve treatment options for patients.

  Recruiting Umeå University · Umeå · NCT05155878

• Blood test for tumor DNA in patients with pancreatic cancer

  This study is testing if a blood test for tumor DNA can help doctors understand how well treatment is working for people with pancreatic cancer.

  Recruiting at 2 sites University of Oklahoma · Oklahoma City, Oklahoma and 1 other locations · NCT05052671

• Analyzing solid tumors for HLA loss and collecting T cells for CAR T-cell therapy

  This study is testing how often solid tumors lose a key protein that helps the immune system recognize them, while also collecting T cells from patients with high-risk cancers to prepare for future CAR T-cell therapy.

  Recruiting at 13 sites A2 Biotherapeutics Inc. · Gilbert, Arizona and 15 other locations · NCT04981119

• Research on early detection of pancreatic cancer

  This study is trying to find better ways to detect pancreatic cancer early by looking at people who are at high risk because of their family history or genetics.

  Recruiting at 57 sites Arbor Research Collaborative for Health · Phoenix, Arizona and 61 other locations · NCT04970056

• Using virtual reality to help manage pain in GI cancer patients

  This study is testing if virtual reality can help people with GI cancer manage their severe abdominal pain better than standard treatments.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT04907643

• ctDNA as a biomarker to guide treatment for non-metastatic pancreatic cancer

  This study tests whether measuring pancreatic cancer DNA in the blood can help doctors understand how patients respond to chemotherapy and surgery.

  Recruiting at 3 sites Northwestern University · DeKalb, Illinois and 2 other locations · NCT04616131

• Using a new imaging probe to detect tissue damage from radiation in lung and pancreatic cancer patients

  This study is testing a new imaging probe to see if it can help find tissue damage from radiation in lung and pancreatic cancer patients.

  Recruiting Phase 2 Massachusetts General Hospital · Boston, Massachusetts · NCT04485286

• Understanding pancreatic cysts and their risks

  This study is trying to understand pancreatic cysts better to help doctors tell which ones are harmless and which ones might be dangerous, so patients can avoid unnecessary tests and surgeries.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT04473794

• Investigating BCA101 for advanced solid tumors driven by EGFR

  This study is testing a new treatment called BCA101 to see if it can help people with advanced solid tumors that are driven by EGFR, especially those who haven't responded to other therapies.

  Recruiting at 21 sites Phase 1 Bicara Therapeutics · La Jolla, California and 20 other locations · NCT04429542

• Treatment for metastatic cancer with BRCA or PALB2 mutations using chemotherapy and stem cells

  This study is testing a new treatment combining chemotherapy and stem cells for people with metastatic pancreatic or breast cancer who have BRCA or PALB2 mutations to see if it is safe and effective.

  Recruiting Phase 1 General Oncology, Inc. · Boston, Massachusetts and 1 other locations · NCT04150042

• Using MRI to guide radiation therapy for various cancers

  This study is testing if using MRI scans to adjust radiation therapy can help people with different types of cancer, like pancreatic and lung cancer, feel better and control their tumors more effectively.

  Recruiting at 2 sites Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT04115254

• Registry for patients with pancreatic ductal adenocarcinoma

  This study is collecting information from people newly diagnosed with pancreatic cancer to help improve understanding and treatment of the disease.

  Recruiting University of Ulm · Ulm · NCT04099134

• Infusion of checkpoint inhibitors and chemotherapy for advanced solid tumors

  This study is testing if giving a mix of immune therapy and chemotherapy directly to tumors helps people with advanced cancers feel better compared to the usual way of giving these treatments.

  Recruiting Phase 2/3 Second Affiliated Hospital of Guangzhou Medical University · Guanzhou, Guangdong · NCT03755739

• Examining the link between skinfold thickness and survival in certain cancers

  This study tests if measuring skinfold thickness can help predict how long people with pancreatic, cholangiocarcinoma, and gallbladder cancers might live, especially those struggling with weight loss.

  Recruiting Samsung Medical Center · Seoul · NCT03637569

• Combining chemotherapy with irreversible electroporation for advanced pancreatic cancer

  This study is testing if combining a special treatment called irreversible electroporation with chemotherapy can help people with advanced pancreatic cancer feel better and manage their disease.

  Recruiting Phase 1 University of Louisville · Louisville, Kentucky · NCT03484299

• Infusing iNKT and PD-1+ CD8+ T cells for advanced solid tumors

  This study will try giving people with advanced lung, pancreatic, liver, stomach, or colon cancers infusions of iNKT cells and PD-1+ CD8+ T cells to see if tumors shrink and survival improves.

  Recruiting Phase 1/2 Shanghai Public Health Clinical Center · Shanghai, Shanghai Municipality · NCT03093688

• Registry for patients with pancreatic diseases

  This study is creating a registry to collect information from patients with pancreatic diseases to help researchers understand what causes these conditions and how to prevent them.

  Recruiting at 2 sites Icahn School of Medicine at Mount Sinai · New York, New York and 1 other locations · NCT02775461

• Screening for pancreatic cancer in high-risk individuals

  This study is testing different ways to check for early signs of pancreatic cancer in people who are at high risk due to genetic factors.

  Recruiting at 9 sites Phase 3 Johns Hopkins University · New Haven, Connecticut and 8 other locations · NCT02000089

• Collecting tumor tissue samples from patients undergoing surgery or biopsy for cancer

  This study is collecting tissue samples from cancer patients having surgery or biopsies to see if they can find new ways to treat different types of cancer.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT01915225

NIH-funded research (20)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• SPORE in Pancreas Cancer at MSK: advancing personalized therapy for pancreatic cancer

  A large, multi-year program at Memorial Sloan Kettering aims to tailor pancreatic cancer treatment to each patient’s biology to improve survival and outcomes.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11397466

• How nerves influence pancreatic cancer progression and immune response

  This NIH grant tests whether nerves and nerve signals affect pancreatic cancer growth and the body’s immune response, with findings that could lead to new therapies for people with pancreatic cancer.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11381938

• Overcoming barriers in pancreatic cancer therapy

  A cancer research project that explores how pancreatic tumors resist treatment and how to improve therapies by studying tumor cells and their surrounding environment in animal models.

  NIH research University of Nebraska Medical Center · Omaha, United States · NIH-11334281

• How low oxygen makes pancreatic cancer cells more aggressive

  This project looks at whether low oxygen areas inside pancreatic tumors cause cancer cells to become more aggressive and resist chemotherapy, aiming to help people with pancreatic cancer.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11294358

• How different dietary fats affect pancreatic cancer start and growth

  This project looks at whether specific kinds of high-fat diets speed up or slow the start and growth of pancreatic cancer to help people at risk understand dietary effects.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11184343

• Immune signals that make pancreatic cancer more stem‑like and aggressive

  Looking at whether an immune signal called IL‑22, working through its receptor IL‑22RA1 and STAT3, makes pancreatic ductal adenocarcinoma cells more stem‑like and aggressive to guide future treatments for people with PDAC.

  NIH research Stanford University · Stanford, United States · NIH-11171448

• Memorial Sloan Kettering pancreas cancer program

  This program uses advanced genetic testing and new treatment approaches to try to improve care for people with locally advanced or metastatic pancreas cancer.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11169807

• How nerve cells affect pancreatic cancer growth

  This work looks at how sensory and sympathetic nerve cells change immune responses and help pancreatic cancer progress.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11127669

• Finding ways to improve treatment for pancreatic cancer

  This study is looking at how the environment around pancreatic cancer cells affects their growth and spread, with the goal of finding better treatments that could help patients like you.

  NIH research University of Nebraska Medical Center · Omaha, United States · NIH-11094151

• Investigating how MIF-CD74 signaling affects immune responses in pancreatic cancer.

  This study is looking at how certain immune cells in pancreatic cancer might be holding back the body's ability to fight the disease, and it hopes to find new ways to boost the immune response to help patients with this tough cancer.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11052061

• Understanding how low oxygen levels affect pancreatic cancer behavior

  This study is looking at how low oxygen levels in pancreatic tumors might make some cancer cells tougher and resistant to treatment, with the goal of finding better ways to help patients with pancreatic cancer.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11041175

• Understanding how certain cancer cells respond to new therapies in pancreatic cancer

  This study is looking at why some pancreatic cancer cells respond better to a specific treatment and how a protein called SIRT6 affects this response, with the goal of finding better treatment options for patients with a tough type of pancreatic cancer.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-10997000

• How nerves affect the progression of pancreatic cancer

  This study is looking at how the nerves in the pancreas might affect the growth of pancreatic cancer and whether blocking these nerves could help slow down the disease, with the goal of finding new ways to improve treatment for patients.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10979425

• How dietary fats affect the development of pancreatic cancer

  This study is looking at how different types of fats in our diet might affect the growth of pancreatic cancer, using mice to see how high-fat diets could influence cancer development, which could help us understand how what we eat might impact cancer risk.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10973509

• Understanding immune signals that drive pancreatic cancer growth

  This study is looking at how immune cells and cancer cells work together in pancreatic cancer to understand what helps the cancer grow and come back, with the goal of finding new ways to improve treatment for patients.

  NIH research Stanford University · Stanford, United States · NIH-10927300

• Understanding how some pancreatic cancer patients respond well to treatments

  This study is looking at how certain genes and molecules affect how well patients with advanced pancreatic cancer respond to different treatments, with the hope of finding ways to improve care and survival for everyone facing this tough disease.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-10908413

• Finding new drugs to treat pancreatic cancer

  This study is looking for new treatments for pancreatic cancer by finding ways to block a protein that helps cancer cells grow, which could lead to better options for patients and improve their chances of living longer and feeling better.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10866505

• Understanding how low oxygen levels affect pancreatic cancer cells

  This study is looking at how low oxygen levels in pancreatic cancer tumors change how cancer cells act and use energy, which could help us understand why the cancer becomes more aggressive and how we might find better treatments for it.

  NIH research University of Virginia · Charlottesville, United States · NIH-10831307

• Understanding how pancreatic cancer spreads

  This study is looking into how pancreatic cancer spreads aggressively, using special mouse models that act like human cases, to find ways to create better treatments that could help patients live longer and healthier lives.

  NIH research University of Nebraska Medical Center · Omaha, United States · NIH-10757574

• Targeting cell changes in pancreatic cancer to improve treatment outcomes

  This study is looking at how pancreatic cancer cells adapt to treatments and become tougher to kill, and it's trying to find the best combinations of drugs to help make those treatments work better for patients like you.

  NIH research University of Virginia · Charlottesville, United States · NIH-10670987

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How many Pancreas Cancer clinical trials are recruiting right now?

84, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 24 countries. The most sites are in United States (36 trials), China (16 trials), Egypt (5 trials), France (5 trials), Canada (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 15, Phase 2: 10, Phase 1/2: 8, Phase 3: 6. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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