Understanding pancreatic cysts and their risks

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine the natural history of pancreatic cysts and develop a diagnostic model to differentiate between mucinous and non-mucinous, as well as malignant and non-malignant cysts. By combining clinical, radiologic, and biomarker characteristics, the study seeks to improve the accuracy of current diagnostic tests, which often fail to reliably distinguish between benign and malignant cysts. This could help reduce unnecessary surveillance and surgical procedures for patients with benign cysts. The study will involve adult patients referred for assessment of pancreatic cysts.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients age 18 years and older
* Referred for assessment of a pancreatic cyst.

Exclusion Criteria:

* Medically ill patients with American Society of Anesthesiologists class 4 or greater.
* Inability to provide informed consent.
* Pregnancy or lactation.

Where it's running

• The Johns Hopkins Hospital
  Baltimore, Maryland, United States Recruiting

Study contacts

• Principal investigator: Elham Afghani, MD MPH — Johns Hopkins University
• Study coordinator: Elham Afghani, MD MPH
• Email: eafghan1@jhmi.edu
• Phone: 410-614-6708

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Liquid biopsy biomarkers to detect and monitor pancreatic cancer

  Researchers test blood-based microRNA signals to see if they can identify pancreatic cancer risk or early disease in people with familial or hereditary risk or mucinous cysts.

  Recruiting Università Vita-Salute San Raffaele · Milan, MI · NCT07700992

• Early detection of pancreatic cancer using a blood test

  This study is testing a new blood test to see if it can help find pancreatic cancer earlier in people who are at high risk or show signs of the disease.

  Recruiting Biological Dynamics · San Diego, California · NCT05625529

• Combining surufatinib and camrelizumab with chemotherapy for advanced pancreatic cancer

  This study is testing a new combination of treatments for people with advanced pancreatic cancer to see if it works better than the standard options.

  Recruiting Phase 1/2 Chinese PLA General Hospital · Beijing · NCT05218889

• Energy needs after pancreatic surgery: measuring metabolism to guide nutrition

  This study tests how much energy patients need after pancreatic surgery and compares direct measurements with common estimating methods to see if standard formulas are accurate.

  Recruiting Evangelismos Hospital · Athens, Attica · NCT07703813

• INSPIRE: Putting patient-reported info into multidisciplinary tumor boards

  This study tests whether adding electronic patient-reported outcomes to tumor board discussions can help guide treatment decisions for women with breast, gynecologic, pancreatic cancers and related cancers.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama and 2 other locations · NCT07671937

• Indocyanine green–guided laparoscopic distal pancreatectomy vs standard approach for pancreatic body/tail lesions

  This trial tests whether using indocyanine green (ICG) fluorescence during laparoscopic distal pancreatectomy helps surgeons protect blood flow and structures, compared with the standard approach, in adults with pancreatic body or tail tumors.

  Recruiting Alexandria University · Alexandria · NCT07656571

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.